High Performance Computing Publications

Papers, research, and articles made possible by the HPC team and HPC resources

Publications by Patricia Kovatch

Dean for Scientific Computing and Data Patricia Kovatch contributes to scientific journals and publications as a collaborative and primary author. Read more publications.


Excerpt: Development of a federated learning approach to predict acute kidney injury in adult hospitalized patients with COVID-19 in New York City

Federated learning is a technique for training predictive models without sharing patient-level data, thus maintaining data security while allowing inter-institutional collaboration. We used federated learning to predict acute kidney injury within three and seven days of admission, using demographics, comorbidities, vital signs, and laboratory values, in 4029 adults hospitalized with COVID-19 at five sociodemographically diverse New York City hospitals… Read more

Publications Through Minerva

Minerva’s computing power helps scientists and researchers advance their studies. Many publications feature work made possible through Minerva.


Abstract: Deep learning identified pathological abnormalities predictive of graft loss in kidney transplant biopsies

by Yi Z, Salem F, Menon MC, Keung K, Xi C, et al. February 2022 | Interstitial fibrosis, tubular atrophy, and inflammation are major contributors to kidney allograft failure. Here we sought an objective, quantitative pathological assessment of these lesions to improve predictive utility and constructed a deep-learning-based pipeline recognizing normal vs. abnormal kidney tissue compartments and mononuclear leukocyte infiltrates. Periodic acid- Schiff stained slides of transplant biopsies (60 training and 33 testing) were used to quantify pathological lesions specific for interstitium, tubules and mononuclear leukocyte infiltration. DOI: 10.1016/j.kint.2021.09.028

Research at Mount Sinai

Our mission is to accelerate scientific discovery at Mount Sinai by providing researchers with a scalable high performance computational and data infrastructure along with human expertise for efficient and effective use of these resources. We partner with both internal and external scientists on innovative research to pursue new scientific opportunities, and actively strive for broader engagement and industrial partnerships with the local and state communities for education and workforce development.

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