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BODE2 Publications

An acknowledgement of support from the Icahn School of Medicine at Mount Sinai should appear in a publication of any material, whether copyrighted or not, based on or developed with Mount Sinai-supported computing resources. A stipulation of the National Institutes of Health (NIH) S10 award includes an accurate acknowledgement statement in publications that utilized NIH-funded resources. Click here for accurate acknowledgement statements for BODE2 nodes.

2021-2022
2020-2021
2019-2020

Year 2 (7/2021-7/2022): 85

  1. Amanat F, Thapa M, Lei T, Ahmed SMS, Adelsberg DC, et al. 2021. SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2. Cell 184:3936-48.e10
  2. Beckmann ND, Comella PH, Cheng E, Lepow L, Beckmann AG, et al. 2021. Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children. Nature Communications 12:4854
  3. Bowles KR, Silva MC, Whitney K, Bertucci T, Berlind JE, et al. 2021. ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in <em>MAPT</em> mutation cerebral organoids. Cell 184:4547-63.e17
  4. Carreño JM, Alshammary H, Singh G, Raskin A, Amanat F, et al. 2021. Evidence for retained spike-binding and neutralizing activity against emerging SARS-CoV-2 variants in serum of COVID-19 mRNA vaccine recipients. eBioMedicine 73
  5. Cha HJ, Uyan Ö, Kai Y, Liu T, Zhu Q, et al. 2021. Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture. Nature Communications 12:6241
  6. Chakraborty S, DiBerto JF, Faouzi A, Bernhard SM, Gutridge AM, et al. 2021. A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects. J Med Chem 64:13873-92
  7. Encinas P, Del Real G, Dutta J, Khan Z, van Bakel H, et al. 2021. Evolution of influenza A virus in intensive and free-range swine farms in Spain. Virus Evol 7:veab099-veab
  8. Fullard JF, Lee H-C, Voloudakis G, Suo S, Javidfar B, et al. 2021. Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19. Genome medicine 13:118-
  9. Gitman MR, Alburquerque B, Chung M, van de Guchte A, Sullivan MJ, et al. 2021. Modified methicillin-resistant Staphylococcus aureus detected in neonatal intensive care patients. J Antimicrob Chemother 76:2774-7
  10. Hernandez MM, Gonzalez-Reiche AS, Alshammary H, Fabre S, Khan Z, et al. 2021. Molecular evidence of SARS-CoV-2 in New York before the first pandemic wave. Nature Communications 12:3463
  11. Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, et al. 2021. Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nature communications 12:7132-
  12. Huq AJ, Fulton-Howard B, Riaz M, Laws S, Sebra R, et al. 2021. Polygenic score modifies risk for Alzheimer’s disease in APOE ε4 homozygotes at phenotypic extremes. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring 13:e12226
  13. Kai Y, Li BE, Zhu M, Li GY, Chen F, et al. 2021. Mapping the evolving landscape of super-enhancers during cell differentiation. Genome Biol 22:269-
  14. Kang C, Rostoker R, Ben-Shumel S, Rashed R, Duty JA, et al. 2021. TMEM176B Regulates AKT/mTOR Signaling and Tumor Growth in Triple-Negative Breast Cancer. Cells 10:3430
  15. Kapoor M, Chao MJ, Johnson EC, Novikova G, Lai D, et al. 2021. Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases. Nature Communications 12:5071
  16. Khalil BD, Sanchez R, Rahman T, Rodriguez-Tirado C, Moritsch S, et al. 2021. An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy. Journal of Experimental Medicine 219
  17. Kontorovich AR, Abul-Husn NS. 2021. Retinol Binding Protein 4 as a Screening Biomarker for Hereditary TTR Amyloidosis in African American Adults With <em>TTR</em> V142I. Journal of Cardiac Failure 27:1020-2
  18. Kontorovich AR, Patel N, Moscati A, Richter F, Peter I, et al. 2021. Myopathic Cardiac Genotypes Increase Risk for Myocarditis. JACC: Basic to Translational Science 6:584-92
  19. Letizia AG, Arnold CE, Adhikari BN, Voegtly LJ, Glang L, et al. 2021. Immunological and Genetic Investigation of SARS-CoV-2 Reinfection in an Otherwise Healthy, Young Marine Recruit. Pathogens 10:1589
  20. Li Y-C, Hsu H-HL, Chun Y, Chiu P-H, Arditi Z, et al. 2021. Machine learning-driven identification of early-life air toxic combinations associated with childhood asthma outcomes. The Journal of clinical investigation 131:e152088
  21. Liu H, Plancarte M, Ball EE, Weiss CM, Gonzales-Viera O, et al. 2021. Respiratory Tract Explant Infection Dynamics of Influenza A Virus in California Sea Lions, Northern Elephant Seals, and Rhesus Macaques. Journal of virology 95:e0040321-e
  22. McInerney TW, Fulton-Howard B, Patterson C, Paliwal D, Jermiin LS, et al. 2021. A globally diverse reference alignment and panel for imputation of mitochondrial DNA variants. BMC Bioinformatics 22:417
  23. Ming C, Wang M, Wang Q, Neff R, Wang E, et al. 2021. Whole genome sequencing–based copy number variations reveal novel pathways and targets in Alzheimer’s disease. Alzheimer’s & Dementia n/a
  24. Nilsson-Payant BE, Uhl S, Grimont A, Doane AS, Cohen P, et al. 2021. The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication. Journal of virology 95:e0125721-e
  25. Patiño LH, Ballesteros N, Muñoz M, Castañeda S, Hernández C, et al. 2021. SARS-CoV-2 in Transit: Characterization of SARS-CoV-2 Genomes From Venezuelan Migrants in Colombia. International Journal of Infectious Diseases 110:410-6
  26. Preman P, Tcw J, Calafate S, Snellinx A, Alfonso-Triguero M, et al. 2021. Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques. Molecular Neurodegeneration 16:68
  27. Rodriguez OL, Sharp AJ, Watson CT. 2021. Limitations of lymphoblastoid cell lines for establishing genetic reference datasets in the immunoglobulin loci. PLoS One 16:e0261374
  28. Silvas JA, Vasquez DM, Park J-G, Chiem K, Allué-Guardia A, et al. 2021. Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice. Journal of virology 95:e0040221-e
  29. Soranno DE, Bihorac A, Goldstein SL, Kashani KB, Menon S, et al. 2021. Artificial Intelligence for AKI!Now: Let’s Not Await Plato’s Utopian Republic. Kidney360 3:376-81
  30. Takei Y, Zheng S, Yun J, Shah S, Pierson N, et al. 2021. Single-cell nuclear architecture across cell types in the mouse brain. Science 374:586-94
  31. Team IMW, Committee INS. 2021. Immunophenotyping assessment in a COVID-19 cohort (IMPACC): A prospective longitudinal study. Sci Immunol 6:eabf3733
  32. Tomlinson JE, Wolfisberg R, Fahnøe U, Patel RS, Trivedi S, et al. 2021. Pathogenesis, MicroRNA-122 Gene-Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection. Hepatology 74:1148-63
  33. VanDusen NJ, Lee JY, Gu W, Butler CE, Sethi I, et al. 2021. Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation. Nature Communications 12:4442
  34. Wang L, Sfakianos JP, Beaumont KG, Akturk G, Horowitz A, et al. 2021. Myeloid Cell-associated Resistance to PD-1/PD-L1 Blockade in Urothelial Cancer Revealed Through Bulk and Single-cell RNA Sequencing. Clin Cancer Res 27:4287-300
  35. Wu HM, Goate AM, O’Reilly PF. 2021. Heterogeneous effects of genetic risk for Alzheimer’s disease on the phenome. Translational Psychiatry 11:406
  36. Yu F, Sankaran VG, Yuan G-C. 2021. CUT&RUNTools 2.0: A pipeline for single-cell and bulk-level CUT&RUN and CUT&Tag data analysis. Bioinformatics (Oxford, England) 38:252-4
  37. Badrinath S, Dellacherie MO, Li A, Zheng S, Zhang X, et al. 2022. A vaccine targeting resistant tumours by dual T cell plus NK cell attack. Nature 606(7916):992-998

 

  1. Birnbaum R, Mahjani B, Loos RJF, Sharp AJ. 2022. Clinical Characterization of Copy Number Variants Associated With Neurodevelopmental Disorders in a Large-scale Multiancestry Biobank. JAMA Psychiatry 79:250-9
  2. Carcamo S, Nguyen CB, Grossi E, Filipescu D, Alpsoy A, et al. 2022. Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma. Cell Reports 39
  3. Carreño JM, Alshammary H, Tcheou J, Singh G, Raskin AJ, et al. 2022. Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron. Nature 602:682-8
  4. Chen T-Y, Gonzalez-Kozlova E, Soleymani T, La Salvia S, Kyprianou N, et al. 2022. Extracellular vesicles carry distinct proteo-transcriptomic signatures that are different from their cancer cell of origin. iScience 25:104414
  5. Danziger O, Patel RS, DeGrace EJ, Rosen MR, Rosenberg BR. 2022. Inducible CRISPR activation screen for interferon-stimulated genes identifies OAS1 as a SARS-CoV-2 restriction factor. PLoS Pathog 18:e1010464-e
  6. DeGrace MM, Ghedin E, Frieman MB, Krammer F, Grifoni A, et al. 2022. Defining the risk of SARS-CoV-2 variants on immune protection. Nature 605:640-52
  7. Del Rossi N, Chen JG, Yuan G-C, Dries R. 2022. Analyzing Spatial Transcriptomics Data Using Giotto. Current Protocols 2:e405
  8. Di’Narzo AF, Houten SM, Kosoy R, Huang R, Vaz FM, et al. 2022. Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets. Gastroenterology 162:828-43.e11
  9. Escalera A, Gonzalez-Reiche AS, Aslam S, Mena I, Laporte M, et al. 2022. Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission. Cell host & microbe 30:373-87.e7
  10. Esposito D, Pant I, Shen Y, Qiao RF, Yang X, et al. 2022. ROCK1 mechano-signaling dependency of human malignancies driven by TEAD/YAP activation. Nature Communications 13:703
  11. Farkouh ME, Stone GW, Lala A, Bagiella E, Moreno PR, et al. 2022. Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week. Journal of the American College of Cardiology 79:917-28
  12. Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, et al. 2022. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica 143:33-53
  13. Fiore VG, Gu X. 2022. Similar network compositions, but distinct neural dynamics underlying belief updating in environments with and without explicit outcomes. NeuroImage 247:118821
  14. Forrest IS, Chaudhary K, Vy HMT, Petrazzini BO, Bafna S, et al. 2022. Population-Based Penetrance of Deleterious Clinical Variants. JAMA 327:350-9
  15. Forrest IS, Nadkarni GN, Do R. 2022. Penetrance of Deleterious Clinical Variants—Reply. JAMA 327:1927-
  16. Gao X, Wang Y, Ribeiro CF, Manokaran C, Chang H, et al. 2022. Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer. Molecular Cancer Research 20:673-85
  17. Garg P, Jadhav B, Lee W, Rodriguez OL, Martin-Trujillo A, Sharp AJ. 2022. A phenome-wide association study identifies effects of copy-number variation of VNTRs and multicopy genes on multiple human traits. The American Journal of Human Genetics 109:1065-76
  18. Halfmann PJ, Iida S, Iwatsuki-Horimoto K, Maemura T, Kiso M, et al. 2022. SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters. Nature 603:687-92
  19. Hernandez MM, Banu R, Gonzalez-Reiche AS, van de Guchte A, Khan Z, et al. 2022. Robust clinical detection of SARS-CoV-2 variants by RT-PCR/MALDI-TOF multitarget approach. Journal of Medical Virology 94:1606-16
  20. Kirkpatrick Roubidoux E, Sano K, McMahon M, Carreño JM, Capuano C, et al. 2022. Novel Epitopes of the Influenza Virus N1 Neuraminidase Targeted by Human Monoclonal Antibodies. Journal of virology 96:e0033222-e
  21. Klein RJ, Vertosick E, Sjoberg D, Ulmert D, Rönn A-C, et al. 2022. Prostate cancer polygenic risk score and prediction of lethal prostate cancer. NPJ Precis Oncol 6:25-
  22. Kong Y, Cao L, Deikus G, Fan Y, Mead EA, et al. 2022. Critical assessment of DNA adenine methylation in eukaryotes using quantitative deconvolution. Science 375:515-22
  23. Kulkarni KR, Schafer M, Berner LA, Fiore VG, Heflin M, et al. 2022. An interpretable and predictive connectivity-based neural signature for chronic cannabis use. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
  24. Li S, Jun T, Tyler J, Schadt E, Kao Y-H, et al. 2022. Inpatient Administration of Alpha-1-Adrenergic Receptor Blocking Agents Reduces Mortality in Male COVID-19 Patients. Front Med (Lausanne) 9:849222-
  25. Loftus TJ, Shickel B, Ozrazgat-Baslanti T, Ren Y, Glicksberg BS, et al. 2022. Artificial intelligence-enabled decision support in nephrology. Nature Reviews Nephrology
  26. Machlovi SI, Neuner SM, Hemmer BM, Khan R, Liu Y, et al. 2022. APOE4 confers transcriptomic and functional alterations to primary mouse microglia. Neurobiology of Disease 164:105615
  27. Mack PC, Gomez JE, Rodilla AM, Carreño JM, Hsu C-Y, et al. 2022. Longitudinal COVID-19-vaccination-induced antibody responses and Omicron neutralization in patients with lung cancer. Cancer Cell:S1535-6108(22)00174-X
  28. McKenzie AT, Marx G, Koenigsberg D, Sawyer M, Iida MA, et al. 2022. Interpretable deep learning of myelin histopathology in age-related cognitive impairment. bioRxiv:2022.06.06.495016
  29. Menez S, Moledina DG, Thiessen-Philbrook H, Wilson FP, Obeid W, et al. 2022. Prognostic Significance of Urinary Biomarkers in Patients Hospitalized With COVID-19. Am J Kidney Dis 79:257-67.e1
  30. Mukherjee S, Bandlamudi C, Hellmann MD, Kemel Y, Drill E, et al. 2022. Germline Pathogenic Variants Impact Clinicopathology of Advanced Lung Cancer. Cancer Epidemiology, Biomarkers & Prevention:OF1-OF10
  31. Olsen SN, Godfrey L, Healy JP, Choi YA, Kai Y, et al. 2022. MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape. Molecular cell 82:1140-55.e11
  32. Patel R, Li Z, Zimmerman BS, Fink MY, Wells JD, et al. 2022. Impact of body mass index on the efficacy of aromatase inhibitors in patients with metastatic breast cancer. Breast Cancer Research and Treatment 192:313-9
  33. Petrazzini BO, Chaudhary K, Márquez-Luna C, Forrest IS, Rocheleau G, et al. 2022. Coronary Risk Estimation Based on Clinical Data in Electronic Health Records. Journal of the American College of Cardiology 79:1155-66
  34. Ramírez JD, Castañeda S, Ballesteros N, Muñoz M, Hernández M, et al. 2022. Hotspots for SARS-CoV-2 Omicron variant spread: Lessons from New York City. Journal of medical virology 94:2911-4
  35. Reategui Schwarz E, van de Guchte A, Dupper AC, Caban AB, Nadkarni D, et al. 2022. Everybody nose: molecular and clinical characteristics of nasal colonization during active methicillin-resistant Staphylococcus aureus bloodstream infection. BMC Infect Dis 22:400-
  36. Ricardo AC, Chen J, Toth-Manikowski SM, Meza N, Joo M, et al. 2022. Hispanic ethnicity and mortality among critically ill patients with COVID-19. PLoS One 17:e0268022-e
  37. Richter F, Strasser AS, Suarez-Farinas M, Zhao S, Nadkarni GN, et al. 2022. Neonatal outcomes during the COVID-19 pandemic in New York City. Pediatr Res 91:477-9
  38. Schoenfeld DA, Zhou R, Zairis S, Su W, Steinbach N, et al. 2022. Loss of PBRM1 Alters Promoter Histone Modifications and Activates ALDH1A1 to Drive Renal Cell Carcinoma. Molecular Cancer Research:OF1-OF15
  39. Song X, Ji J, Rothstein JH, Alexeeff SE, Sakoda LC, et al. 2022. MiXcan: a Framework for Cell-Type-Specific Transcriptome-Wide Association Studies with an Application to Breast Cancer. bioRxiv:2022.03.15.484509
  40. Song X, Ru M, Steinsnyder Z, Tkachuk K, Kopp RP, et al. 2022. SNPs at SMG7 Associated with Time from Biochemical Recurrence to Prostate Cancer Death. Cancer Epidemiology, Biomarkers & Prevention:OF1-OF7
  41. Tan J, O’Dell G, Hernandez MM, Sordillo EM, Kahn Z, et al. 2022. Human Anti-neuraminidase Antibodies Reduce Airborne Transmission of Clinical Influenza Virus Isolates in the Guinea Pig Model. Journal of Virology 96:e01421-21
  42. Tantillo GB, Jetté N, Gururangan K, Agarwal P, Marcuse L, et al. 2022. Electroencephalography at the height of a pandemic: EEG findings in patients with COVID-19. Clin Neurophysiol 137:102-12
  43. van der Heide V, Jangra S, Cohen P, Rathnasinghe R, Aslam S, et al. 2022. Limited extent and consequences of pancreatic SARS-CoV-2 infection. Cell reports 38:110508-
  44. Wang C, Lashua LP, Carter CE, Johnson SK, Wang M, et al. 2022. Sex disparities in influenza: A multiscale network analysis. iScience 25:104192
  45. Wang M, Song W-m, Ming C, Wang Q, Zhou X, et al. 2022. Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer’s disease: review, recommendation, implementation and application. Molecular Neurodegeneration 17:17
  46. Xu P, Wang M, Song W-M, Wang Q, Yuan G-C, et al. 2022. The landscape of human tissue and cell type specific expression and co-regulation of senescence genes. Molecular neurodegeneration 17:5-
  47. Zhang L, Chun Y, Ho H-e, Arditi Z, Lo T, et al. 2022. Multiscale study of the oral and gut environments in children with high- and low-threshold peanut allergy. Journal of Allergy and Clinical Immunology
  48. Zheutlin AB, Vieira L, Shewcraft RA, Li S, Wang Z, et al. 2022. Improving postpartum hemorrhage risk prediction using longitudinal electronic medical records. J Am Med Inform Assoc 29:296-305

 

 

Year 1 (7/15/2020-7/15/2021): 64

  1. Basak S, Kumar A, Ramsey S, Gibbs E, Kapoor A, et al. 2020. High-resolution structures of multiple 5-HT3AR-setron complexes reveal a novel mechanism of competitive inhibition. eLife 9:e57870
  2. Breen MS, Garg P, Tang L, Mendonca D, Levy T, et al. 2020. Episignatures Stratifying Helsmoortel-Van Der Aa Syndrome Show Modest Correlation with Phenotype. The American Journal of Human Genetics 107:555-63
  3. Breen MS, Garg P, Tang L, Mendonca D, Levy T, et al. 2020. Episignatures stratifying ADNP syndrome show modest correlation with phenotype. bioRxiv:2020.04.01.014902
  4. Britton GJ, Contijoch EJ, Spindler MP, Aggarwala V, Dogan B, et al. 2020. Defined microbiota transplant restores Th17/RORγt<sup>+</sup> regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas. Proceedings of the National Academy of Sciences 117:21536-45
  5. Cravedi P, Fribourg M, Zhang W, Yi Z, Zaslavsky E, et al. 2020. Distinct peripheral blood molecular signature emerges with successful tacrolimus withdrawal in kidney transplant recipients. American Journal of Transplantation 20:3477-85
  6. Diaz JEL, Ahsen ME, Schaffter T, Chen X, Realubit RB, et al. 2020. The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies. eLife 9:e52707
  7. Esai Selvan M, Zauderer MG, Rudin CM, Jones S, Mukherjee S, et al. 2020. Inherited Rare, Deleterious Variants in <em>ATM</em> Increase Lung Adenocarcinoma Risk. Journal of Thoracic Oncology 15:1871-9
  8. Hammerstad SS, Blackard JT, Lombardi A, Owen RP, Concepcion E, et al. 2020. Hepatitis C Virus Infection of Human Thyrocytes: Metabolic, Hormonal, and Immunological Implications. J Clin Endocrinol Metab 105:1157-68
  9. Hartzell S, Bin S, Cantarelli C, Haverly M, Manrique J, et al. 2020. Kidney Failure Associates With T Cell Exhaustion and Imbalanced Follicular Helper T Cells. Front Immunol 11:583702-
  10. Lavin KM, Ge Y, Sealfon SC, Nair VD, Wilk K, et al. 2020. Rehabilitative Impact of Exercise Training on Human Skeletal Muscle Transcriptional Programs in Parkinson’s Disease. Front Physiol 11:653-
  11. Lavin KM, Sealfon SC, McDonald M-LN, Roberts BM, Wilk K, et al. 2020. Skeletal muscle transcriptional networks linked to type I myofiber grouping in Parkinson’s disease. J Appl Physiol (1985) 128:229-40
  12. Letizia AG, Ramos I, Obla A, Goforth C, Weir DL, et al. 2020. SARS-CoV-2 Transmission among Marine Recruits during Quarantine. N Engl J Med 383:2407-16
  13. Li W, Bicak M, Sjoberg DD, Vertosick E, Dahlin A, et al. 2020. Genome-wide association study identifies novel single nucleotide polymorphisms having age-specific effect on prostate-specific antigen levels. The Prostate 80:1405-12
  14. Martin-Trujillo A, Patel N, Richter F, Jadhav B, Garg P, et al. 2020. Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles. PLoS Genet 16:e1009189-e
  15. Miner GH, Renton AE, Taubenfeld E, Tadros RO, Marcora E, et al. 2020. Whole genome sequencing identifies loci specifically associated with thoracic aortic wall defects and abdominal aortic aneurysms in patients with European ancestry. JVS: Vascular Science 1:233-45
  16. Nair VD, Ge Y, Li S, Pincas H, Jain N, et al. 2020. Sedentary and Trained Older Men Have Distinct Circulating Exosomal microRNA Profiles at Baseline and in Response to Acute Exercise. Front Physiol 11:605-
  17. Papa L, Djedaini M, Martin TC, Zangui M, Beaumont KG, et al. 2020. Limited Mitochondrial Activity Coupled With Strong Expression of CD34, CD90 and EPCR Determines the Functional Fitness of ex vivo Expanded Human Hematopoietic Stem Cells. Front Cell Dev Biol 8:592348-
  18. Roudko V, Bozkus CC, Orfanelli T, McClain CB, Carr C, et al. 2020. Shared Immunogenic Poly-Epitope Frameshift Mutations in Microsatellite Unstable Tumors. Cell 183:1634-49.e17
  19. Sieh W, Rothstein JH, Klein RJ, Alexeeff SE, Sakoda LC, et al. 2020. Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk. Nature Communications 11:5116
  20. Wang L, Timsina P, Pandey G. Computational performance of heterogeneous ensemble frameworks on high-performance computing platforms. Proc. 2020 IEEE International Conference on Big Data (Big Data), 2020:2843-50:
  21. Wang X, Liu R, Zhang W, Hyink DP, Das GC, et al. 2020. Role of SIRT1 in HIV-associated kidney disease. American Journal of Physiology-Renal Physiology 319:F335-F44
  22. Wu H, Wei M, Jiang X, Tan J, Xu W, et al. 2020. lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis. Molecular Therapy – Nucleic Acids 20:438-50
  23. Yi Z, Keung KL, Li L, Hu M, Lu B, et al. 2020. Key driver genes as potential therapeutic targets in renal allograft rejection. JCI Insight 5:e136220
  24. Zhang Z, Menon MC, Zhang W, Stahl E, Loza B-L, et al. 2020. Genome-wide non-HLA donor-recipient genetic differences influence renal allograft survival via early allograft fibrosis. Kidney International 98:758-68
  25. Bao R, Ng A, Sasaki M, Esai Selvan M, Katti A, et al. 2021. Functional Common and Rare <em>ERBB2</em> Germline Variants Cooperate in Familial and Sporadic Cancer Susceptibility. Cancer Prevention Research 14:441-54
  26. Belbin GM, Cullina S, Wenric S, Soper ER, Glicksberg BS, et al. 2021. Toward a fine-scale population health monitoring system. Cell 184:2068-83.e11
  27. Bendl J, Hauberg ME, Girdhar K, Im E, Vicari JM, et al. 2021. The three-dimensional landscape of chromatin accessibility in Alzheimer’s disease. bioRxiv:2021.01.11.426303
  28. Britton GJ, Chen-Liaw A, Cossarini F, Livanos AE, Spindler MP, et al. 2021. Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19. Scientific Reports 11:13308
  29. Cao A, Li J, Asadi M, Basgen JM, Zhu B, et al. 2021. DACH1 protects podocytes from experimental diabetic injury and modulates PTIP-H3K4Me3 activity. The Journal of Clinical Investigation 131
  30. Crawford AA, Bankier S, Altmaier E, Barnes CLK, Clark DW, et al. 2021. Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease. Journal of Human Genetics 66:625-36
  31. da Cruz HF, Pfahringer B, Martensen T, Schneider F, Meyer A, et al. 2021. Using interpretability approaches to update “black-box” clinical prediction models: an external validation study in nephrology. Artificial Intelligence in Medicine 111:101982
  32. Estill M, Ribeiro E, Francoeur NJ, Smith ML, Sebra R, et al. 2021. Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment. Scientific Reports 11:6729
  33. Forrest IS, Chaudhary K, Vy HMT, Bafna S, Jordan DM, et al. 2021. Ancestrally and Temporally Diverse Analysis of Penetrance of Clinical Variants in 72,434 Individuals. medRxiv:2021.03.11.21253430
  34. Hernandez MM, Gonzalez-Reiche AS, Alshammary H, Fabre S, Khan Z, et al. 2021. Before the Surge: Molecular Evidence of SARS-CoV-2 in New York City Prior to the First Report. medRxiv:2021.02.08.21251303
  35. Ho JSY, Mok BW-Y, Campisi L, Jordan T, Yildiz S, et al. 2021. TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation. Cell 184:2618-32.e17
  36. Jatiani SS, Christie S, Leshchenko VV, Jain R, Kapoor A, et al. 2021. SOX11 Inhibitors Are Cytotoxic in Mantle Cell Lymphoma. Clinical Cancer Research
  37. Johnson JS, Cote AC, Dobbyn A, Sloofman LG, Xu J, et al. 2021. The Phenome-wide Consequences of Anorexia Nervosa Genes. medRxiv:2021.02.12.21250941
  38. Khalil BD, Sanchez R, Rahman T, Rodriguez-Tirado C, Moritsch S, et al. 2021. A specific agonist of the orphan nuclear receptor NR2F1 suppresses metastasis through the induction of cancer cell dormancy. bioRxiv:2021.01.30.428967
  39. Kirkpatrick Roubidoux E, McMahon M, Carreño JM, Capuano C, Jiang K, et al. 2021. Identification and Characterization of Novel Antibody Epitopes on the N2 Neuraminidase. mSphere 6:e00958-20
  40. Kontorovich AR, Tang Y, Patel N, Georgievskaya Z, Shadrina M, et al. 2021. Burden of Cardiomyopathic Genetic Variation in Lethal Pediatric Myocarditis. Circulation: Genomic and Precision Medicine 0
  41. Kulkarni KR, Schafer M, Berner L, Fiore VG, Heflin M, et al. 2021. An interpretable connectivity-based decoding model for classification of chronic marijuana use. bioRxiv:2021.05.04.442433
  42. LEHRER S, RHEINSTEIN PH. 2021. Homozygosity for rs17775810 Minor Allele Associated With Reduced Mortality of COVID-19 in the UK Biobank Cohort. In Vivo 35:965-8
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  44. Li W, Klein RJ. 2021. Genome-wide association study identifies a role for the progesterone receptor in benign prostatic hyperplasia risk. Prostate Cancer and Prostatic Diseases 24:492-8
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