Congratulations to Grace, Tom, Alon, and James for the publication of their review “Looking beyond the intervertebral disc: the need for behavioral assays in models of discogenic pain” in the Annals of the New York Academy of Sciences!
Tag Archives: spine
ORS Spine Section Symposium at TERMIS
Dr. Iatridis co-chaired the “Challenges and opportunities in annulus fibrosis repair” symposium with Dr. Zhen Li. The symposium was held at the TERMIS-EU meeting in Davos, Switzerland, June 26-27.
The group also enjoyed the beautiful Switzerland scenery!
Annual ORL Summer Rowboating in Central Park
The ORL embarked on its annual rowboat adventure in Central Park on August 4th, 2017!
See this post from the Huang Laboratory Page for more!
Rose Long defends her dissertation!
Congratulations to Rose Long for successfully defending her dissertation! Rose was very productive during her PhD studies and developed many elegant methods for evaluating tissue engineering repair materials for injured intervertebral discs. Her dissertation was entitled “Repair of Herniated Intervertebral Discs: Designing and Translating Annulus Fibrosus Sealants”.
Summer Celebrations
The Iatridis lab celebrates the start of the summer and welcomes summer students at the Boat Basin Cafe.
ISSLS Annual Meeting – May 29-June 2
The 44th Annual Meeting of ISSLS took place in Athens, Greece from May 29th to June 2nd, 2017. Dr. Iatridis moderated 1 session (Disc Regeneration) and provided 2 podium presentations: “Hyperosmolar overloading induces notochordal cell differentiation with osmosensitive aquaporin3 upregulation and altered N-cadherin and connexin-43 expression” and “Bioactive dietary polyphenol preparation for preventing painful behavior associated with lumbar disc degeneration: an in-vivo rat model”.
Mount Sinai Spine Research Day – May 18
The Sinai Spine Research Day on May 18th highlights the latest clinical and basic science spine research and demonstrates the strong commitment to promote research that answers critical scientific questions while also improving clinical care. This year, four members of the spine lab will be giving presentations:
Alon Lai: “Bioactive dietary polyphenol preparation for preventing painful behavior associated with lumbar disc degeneration”
Thomas Evashwick-Rogler: “Hyperosmolar overloading induces notochordal cell differentiation with osmosensitive Aquaporin3 upregulation and altered Ncadherin and Connexin43 expression”
Rose Long: “Repair of annular injury using a fibrin based sealant in ovine after one year”
Olivia Torre: “Development of an in vivo model of neonatal intervertebral disc injury and regeneration”
5/18/2017
Welcome to Nimrod Korda!
Welcome to Nimrod Korda who joins the lab as our student intern. Nimrod will receive his BS from the ORT Braude College of Engineering in Israel where he was a part of Dr. Sarit Sivan’s lab. For his research, Nimrod will be working on characterizing a GAG-mimetic hydrogel for nucleus pulposus replacement.
Welcome to Kengo Fujii!
Welcome to Dr. Kengo Fujii who joins the lab for a research year as a postdoctoral fellow. Dr. Fujii is a visiting orthopaedic surgeon from the University of Tsukuba in Japan. For his postdoctoral research, Dr. Fujii will apply his expertise to intervertebral disc biomechanics and mechanisms of discogenic pain.
ORS 2017 Recap
The Spine Lab and collaborators successfully presented 10 abstracts this year at ORS in San Diego
- Rolfe RA, Oyen ML, Iatridis JC, Nowlan NC: Short Periods of Fetal Immobility Lead to Dramatic Effects on Spine and Rib Development, Paper #: 212.
- Long RG, Nakai T, Sakai D, Iatridis JC, Alini M, Grad S, Li Z: TGFβ1 induces a contractile CD146+ phenotype of human annulus fibrosus cells and may be delivered in a carrier for annulus fibrosus repair, Poster #: 1793.
- Torre OM, Das R, Mosley GE, Huang AH, Iatridis JC: Development of an In Vivo Model of Neonatal Intervertebral Disc Injury and Regeneration, Poster #: 1829.
- Cruz MA, Hom WW, Merril R, Torre OM, Nasser P, Hecht AC, Illien-Junger S, Iatridis JC: Cell-Seeded Adhesive Biomaterial for Repair of Annulus Fibrosus Defects in Intervertebral Discs, Transactions of the Orthopaedic Research Society, Poster Session: PS2-120, Spine – Disc, Tissue Engineering and Repair, Poster #: 1800, 2017.
- Lin HA, Varma DM, Hom WW, Cruz MA, Nasser PR, Iatridis JC, Nicoll SB: Injectable Cellulosic Hydrogels as Nucleus Pulposus Replacements: Assessment of Herniation Risk, Fatigue Behavior, and In Vivo Biocompatibility, Transactions of the Orthopaedic Research Society, Poster Session: PS2-120, Spine – Disc, Tissue Engineering and Repair, Poster #: 1799, 2017.
- Lai A, Evashwick-Rogler TW, Salandra JM, Ho L, Laudier DM, Cho SK, Hecht AC, Winkelstein BA, Pasinetti GM Iatridis JC: A Potential Safe and Novel Drink For Preventing Pain Associated With Disc Degeneration – An In-Vivo Rat Model, Transactions of the Orthopaedic Research Society, Poster session: PS2-121, Poster # 1839, 2017.
- Evashwick-Rogler TW, Lai A, Salandra JM, Purmessur D, Skovrlj B, Winkelstein BA, Cho SK, Hecht Ac, Iatridis JC: Disc height loss, but not Pro-inflammatory cytokine or Substance P expression, Predicts Intervertebral Disc Degeneration-Related Pain in a Rat Model, Transactions of the Orthopaedic Research Society, Poster Session: PS1-044, Spine – Disc Biology, Poster #: 854, 2017.
- Palacio-Mancheno P, Evashwick-Rogler TW, Laudier DM, Purmessur D, Iatridis JC: Hyperosmolar Overloading in a Mouse Organ Culture Model Induces Notochordal Cell Differentiation with Osmoregulatory Aquaporin3 Upregulation and Altered N-Cad and Connexin-43 Mechanotransduction Expression, Transactions of the Orthopaedic Research Society, Poster Session: PS2-121, Spine – Disc Biology, Poster # 1817, 2017.
- Palacio-Mancheno P, Kindschuh WF, Chen X, Harned AA, Iatridis JC: Illien-Jünger S: Age- and Sex-Dependent Effects of Advanced Glycation Endproducts Ingestion on Vertebral Bone Quality and Function, Transactions of the Orthopaedic Research Society, Poster Session: PS1-029, Bone – Musculoskeletal Development and Aging, Poster #: 0672, 2017.
- Gluck MJ, Beck CM, Vijayaraghavan S, Iatridis JC, Hausman MR: In Situ Imaging of Rat Median Nerve Damage Using Second Harmonic Generation Microscopy: Advancing Towards an In Vivo Application, Transactions of the Orthopaedic Research Society, Poster Session: PS2-152, Diagnostic Imaging, Poster #: 2241, 2017.
James Iatridis also Chaired the ORS Spine Section Meeting and became 2nd Vice President of the ORS. We enjoyed being part of the Van Mow academic tree during his Shands Award Presentation #VanMow #ORS2017.
In addition to research activities, most of the Orthopaedic Research Lab attendees met at Tom Evashwick-Rogler’s family home for a great barbeque in celebration of a very successful meeting.
