Tag Archives: presentation

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ORS Acceptances!

Congratulations to the team on the excellent ORS abstract acceptances! We are proud of the diverse and exciting work submitted and accepted this year!

  1. Torre OM, Das R, Berenblum RE, Huang AH, Iatridis JC: Neonatal mice intervertebral discs restore function following herniation injury, Transactions of the Orthopaedic Research Society, Session 013, Podium Presentation #: 0068, 2018.
  2. Torre OM, Evashwick-Rogler TW, Iatridis JC: Optimizing Biomechanical Loading Protocols Ex Vivo to Improve Detection of Mild Intervertebral Disc Injuries, Transactions of the Orthopaedic Research Society, PS1-054, Poster #: 0771, 2018.
  3. Krishnamoorthy D, Liu X, Lin L, Xue P, Zhang E, Zhang F, Linhardt RJ, Iatridis JC: Characterization of human lumbar intervertebral disc glycosaminoglycan sulfation patterns using multiple reaction monitoring with liquid chromatography- mass spectrometry, Transactions of the Orthopaedic Research Society, PS1-053, Poster #: 0748, 2018.
  4. Krishnamoorthy D, Torre OM, Natelson D, Smith M, Iatridis JC, Illien-Jünger S: Dietary advanced glycation end product consumption leads to mechanical stiffening of murine intervertebral discs, Transactions of the Orthopaedic Research Society, PS2-152, Poster #: 1630, 2018.
  5. Mui B, DiStefano T, Hecht AC, Iatridis JC: Hydrogel formulation and culture conditions influence TGF- β3 release kinetics and extracellular matrix elaboration in genipin-crosslinked fibrin for annulus fibrosus repair, Transactions of the Orthopaedic Research Society, PS2-154, Poster #: 1666, 2018.
  6. Hom WW, Lin HA, Korda N, Desai JS, Nasser P, Hecht AC, Nicoll SB, Iatridis JC: Ex vivo biomechanical evaluation of a combined annulus fibrosus and nucleus pulposus hydrogel repair in a large animal model of severe intervertebral disc herniation injury, Transactions of the Orthopaedic Research Society, Spine: Modeling and Mechanics, Session 38, Podium Presentation #: 0216, 2018.
  7. Mosley GE, Evashwick-Rogler TW, Kaseta T, Lai A, Iatridis JC: Sex differences in rat lumbar intervertebral discs following annular puncture injury, Transactions of the Orthopaedic Research Society, PS2-152, Poster #: 1641, 2018.
  8. Zhou GK, Bradley EW, Westendorf JJ, Iatridis JC, Illien-Junger S: Role of Phlpp1 in Cell Proliferation and Apoptosis in Intervertebral Discs, Transactions of the Orthopaedic Research Society, PS1-053, Poster #:  0750, 2018.
  9. Real A, Ukogu C, Hecht AC, Iatridis JC: Elevated Glycohemoglobin HbA1c is Associated with Low Back Pain Independent of BMI, Transactions of the Orthopaedic Research Society, PS1-058, Poster #: 0802, 2018.
  10. Gluck MJ, Beck CM, Skodras A, Laudier D, Fowkes ME, Iatridis JC, Cagle PJ, Hausman MR: In Vivo Monitoring of Nerve Structure and Function Following Neural Stretch Injury via SHG Microscopy and Intra-Operative Nerve Stimulation, Transactions of the Orthopaedic Research Society, Session 056, Podium Presentation #: 0308, 2018.
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ORS PSRS 2017

The Iatridis & Illien-Junger Labs had a great time at the ORS PSRS 4th International Spine Research Symposium in Lake Harmony PA! Chaired by Makarand Risbud, PSRS is a unique meeting in which prominent investigators and trainees in the spine research community come together to share their latest findings, trends, and ideas.

Congratulations to our PhD Candidate, Olivia Torre, on being a recipient of the “ORS PSRS Trainee Podium Award for Outstanding Scientific Research”! Her presentation, “Functional Restoration of Intervertebral Disc Biomechanics Following Neonatal Herniation Injury,” was delivered during the ‘Disc Biomechanics and Imaging’ session on October 26th, 2017.

Congratulations to Assistant Professor, Dr. Svenja Illien-Junger, on being a recipient of the Young Investigator Award. Dr. Illien-Junger advises ORL’s MS student, George Zhao, who presented the poster, “Phlpp1 in Cell Proliferation and Apoptosis During IVD Growth and Degeneration,” during the second poster session on October 25th, 2017.

In addition to these awards, Dr. Iatridis gave a fantastic talk titled, “Annulus Fibrosus Injury, Repair, and Regeneration” and Dr. Krishnamoorthy presented her poster, “Characterization of Human Lumbar Intervertebral Disc Glycosaminoglycan Sulfation Patterns using Multiple Reaction Monitoring with Liquid Chromatography-mass Spectrometry”.

We are very proud of these achievements and we look forward to ORL’s future research successes!

In addition to presenting our research and networking within the community, the Spine Lab enjoyed the time away from NYC in the Poconos.

Team learns about disc pathobiology:

Dr. James Iatridis giving his talk:

 Olivia receiving her award:

Svenja receiving her award:

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Einstein Meeting 2017

Thursday, October 19th marked the 6th annual Musculoskeletal Repair and Regeneration Symposium hosted by the Albert Einstein College of Medicine. Orthopaedic research at Mount Sinai was well represented at the meeting with multiple posters and a talk from Dr. James Iatridis on annulus fibrosis repair in a large animal model. Most excitingly, Olivia Torre was named one of three winners of the Young Investigator Award for graduate students and postdoctoral fellows for her work on injury and regeneration in the neonatal mouse intervertebral disc.

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Take a look at the Huang Laboratory Page for a Related Post!

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Sun Valley Invited Presentation

James attended the ORS Musculoskeletal Biology Workshop at Sun Valley!  He participated in the panel discussion “Grant Writing Advice for Junior Investigators”. He also chaired and presented at the session entitled “Problems in Orthopaedics: Degenerative Disk Disease” with Drs. Mak Risbud and James Kang.

Hiking in Sawtooth National Forest with Dr. Jim Kang and also with conference organizers Drs. David Burr and Teresita Bellido.

 

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ISSLS Annual Meeting – May 29-June 2

The 44th Annual Meeting of ISSLS took place in Athens, Greece from May 29th to June 2nd, 2017. Dr. Iatridis moderated 1 session (Disc Regeneration) and provided 2 podium presentations: “Hyperosmolar overloading induces notochordal cell differentiation with osmosensitive aquaporin3 upregulation and altered N-cadherin and connexin-43 expression” and “Bioactive dietary polyphenol preparation for preventing painful behavior associated with lumbar disc degeneration: an in-vivo rat model”.

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ORS 2017 Recap

The Spine Lab and collaborators successfully presented 10 abstracts this year at ORS in San Diego

  1. Rolfe RA, Oyen ML, Iatridis JC, Nowlan NC: Short Periods of Fetal Immobility Lead to Dramatic Effects on Spine and Rib Development, Paper #: 212.
  2. Long RG, Nakai T, Sakai D, Iatridis JC, Alini M, Grad S, Li Z: TGFβ1 induces a contractile CD146+ phenotype of human annulus fibrosus cells and may be delivered in a carrier for annulus fibrosus repair, Poster #: 1793.
  3. Torre OM, Das R, Mosley GE, Huang AH, Iatridis JC: Development of an In Vivo Model of Neonatal Intervertebral Disc Injury and Regeneration, Poster #: 1829.
  4. Cruz MA, Hom WW, Merril R, Torre OM, Nasser P, Hecht AC, Illien-Junger S, Iatridis JC: Cell-Seeded Adhesive Biomaterial for Repair of Annulus Fibrosus Defects in Intervertebral Discs, Transactions of the Orthopaedic Research Society, Poster Session: PS2-120, Spine – Disc, Tissue Engineering and Repair, Poster #: 1800, 2017.
  5. Lin HA, Varma DM, Hom WW, Cruz MA, Nasser PR, Iatridis JC, Nicoll SB: Injectable Cellulosic Hydrogels as Nucleus Pulposus Replacements: Assessment of Herniation Risk, Fatigue Behavior, and In Vivo Biocompatibility, Transactions of the Orthopaedic Research Society, Poster Session: PS2-120, Spine – Disc, Tissue Engineering and Repair, Poster #: 1799, 2017.
  6. Lai A, Evashwick-Rogler TW, Salandra JM, Ho L, Laudier DM, Cho SK, Hecht AC, Winkelstein BA,  Pasinetti GM Iatridis JC: A Potential Safe and Novel Drink For Preventing Pain Associated With Disc Degeneration – An In-Vivo Rat Model, Transactions of the Orthopaedic Research Society, Poster session: PS2-121, Poster # 1839, 2017.
  7. Evashwick-Rogler TW, Lai A, Salandra JM, Purmessur D, Skovrlj B, Winkelstein BA, Cho SK, Hecht Ac, Iatridis JC: Disc height loss, but not Pro-inflammatory cytokine or Substance P expression, Predicts Intervertebral Disc Degeneration-Related Pain in a Rat Model, Transactions of the Orthopaedic Research Society, Poster Session: PS1-044, Spine – Disc Biology, Poster #: 854, 2017.
  8. Palacio-Mancheno P, Evashwick-Rogler TW, Laudier DM, Purmessur D, Iatridis JC: Hyperosmolar Overloading in a Mouse Organ Culture Model Induces Notochordal Cell Differentiation with Osmoregulatory Aquaporin3 Upregulation and Altered N-Cad and Connexin-43 Mechanotransduction Expression, Transactions of the Orthopaedic Research Society, Poster Session: PS2-121, Spine – Disc Biology, Poster # 1817, 2017.
  9. Palacio-Mancheno P, Kindschuh WF, Chen X, Harned AA, Iatridis JC: Illien-Jünger S: Age- and Sex-Dependent Effects of Advanced Glycation Endproducts Ingestion on Vertebral Bone Quality and Function, Transactions of the Orthopaedic Research Society, Poster Session: PS1-029, Bone – Musculoskeletal Development and Aging,  Poster #: 0672, 2017.
  10. Gluck MJ, Beck CM, Vijayaraghavan S, Iatridis JC, Hausman MR: In Situ Imaging of Rat Median Nerve Damage Using Second Harmonic Generation Microscopy: Advancing Towards an In Vivo Application, Transactions of the Orthopaedic Research Society, Poster Session: PS2-152, Diagnostic Imaging, Poster #: 2241, 2017.

James Iatridis also Chaired the ORS Spine Section Meeting and became 2nd Vice President of the ORS. We enjoyed being part of the Van Mow academic tree during his Shands Award Presentation #VanMow #ORS2017.

In addition to research activities, most of the Orthopaedic Research Lab attendees met at Tom Evashwick-Rogler’s family home for a great barbeque in celebration of a very successful meeting.

 

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5th Annual Musculoskeletal Repair and Regeneration Symposium – October 13, 2016

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Organizers and speakers of the 5th Annual Musculoskeletal Repair and Regeneration Symposium

The Mount Sinai ORL attended the 5th Annual Musculoskeletal Repair and Regeneration Symposium at Albert Einstein College of Medicine on October 13, 2016. The symposium mission is “to expand the knowledge base within the field, and to foster creativity, collaboration and networking between researchers throughout the region.”

During the symposium, Dr. Alice Huang gave a presentation entitled “Regulation of tendon regeneration” and Dr. James Iatridis presented his talk entitled “Injury, inflammation, and altered mechanotransduction in the intervertebral disc” while also serving as the Steering Chair for the “Novel views into musculoskeletal degenerative diseases” session. In addition, Rose Long presented her poster, “CD146+ phenotype of human annulus fibrosus cells induced by TGFβ1 has affinity to collagen scaffold aimed for annulus fibrosus repair” and together Matthew Gluck and Christina Beck presented their posters “In Situ Imaging of Rat Median Nerve Damage Using SHG Microscopy: Advancing Towards an In Vivo Application” and “Biomechanical Analysis of the Reduction and Association of the Scaphoid and Lunate (RASL) Technique: Screw Trajectory Matters”.

More information about the symposium can be found here:https://www.einstein.yu.edu/departments/orthopaedic-surgery/symposium/

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Gordon Research Conference and Seminar – August 7-12, 2016

Paolo Palacio-Mancheno, Rose Long and Olivia Torre of the Iatridis lab attended the Musculoskeletal Biology & Bioengineering Gordon Research Conference and Seminar at the Proctor Academy in Andover, NH August 7-12, 2016. The theme of the 2016 GRC was “Stepping Across Disciplines to Spur Innovation in Musculoskeletal Biology and Bioengineering” as the goal of the conference was to bring together leaders in the field of musculoskeletal biology and bioengineering to foster new scientific interactions across the field.

During the week long conference, Dr. James Iatridis presented a keynote lecture entitled “Injury, Inflammation, and Altered Mechanotransduction in the Intervertebral Disc” and Rose Long presented a seminar entitled “Induction of Cd146+ Phenotype by Tgfb1 from Human Annulus Fibrosis Cells for Annulus Repair”.  In addition, both Paolo Palacio-Mencheno and Olivia Torre presented their posters “Hyperosmolar Conditions Induce Notochordal Cell Maturation and Matrix Production with Aquaporin3 Upregulation in Nucleus Pulposus” and “Hyperosmolar Conditions Induce Notochordal Cell Maturation and Matrix Production with Aquaporin3 Upregulation in Nucleus Pulposus”, respectively.

Read more about the conference here: https://www.grc.org/programs.aspx?id=10990