Category Archives: Research

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ORS PSRS 3rd International Spine Research Symposium

PSRS-Awards-2015

Mount Sinai Spine was an important sponsor of the ORS PSRS Spine Research Symposium. Many members of the Spine Lab participated in this meeting. Dr. Iatridis was an invited faculty who gave a talk entitled ‘Annulus Fibrosus Repair Strategies in the Intervertebral Disc’. Alumnus, Dr. Devina Purmessur, was an invited speaker on the Special Rising Star Session organized by the ORS Spine Section, and gave a talk on ‘The Role of the IVD Microenvironment on Neurovascular Ingrowth’. Dr. Alon Lai and Visiting Professor, Dr. Hironobu Watanabe (Keiyu Spine Center, Keiyu Orthopedic Hospital, Tatebayashi, Gunma), received a 1st Place Poster Award in the ‘Preclinical, Animal Models, and Clinical’ session (http://www.ors.org/ors-psrs-award-recipients/).

http://www.ors.org/philaspinemeeting/

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Accepted abstracts for ORS 2016

 

  1. Rolfe RA, Oyen ML, Iatridis JC, Nowlan NC: Mechanical Stimulation is required for normal spinal curvature and vertebral segmentation in the developing chick, Transactions of the Orthopaedic Research Society, 2016, Poster # 0852.
  2. Watanabe H, Lai A, Schuchman M, Cho SK, Hecht AC, Iatridis JC: Can Intradiscal Injection with TNF-α Inhibitor Reduce Pain and Disc Degeneration in a Rat Model?, Can Intradiscal Injection with TNF-α Inhibitor Reduce Pain and Disc Degeneration in a Rat Model?, Transactions of the Orthopaedic Research Society, 2016, Poster # 0875.
  3. Nakazawa KR, Walter BA, Laudier DM, Spiller KL, Iatridis JC: Exogenous and Endogenous Macrophage Phenotypes and Localization in Human Intervertebral Disc Degeneration, Transactions of the Orthopaedic Research Society, 2016, Poster # 0891.
  4. Lai A, Watanabe H, Ho L, Cho SK, Hecht AC, Pasinetti GM, Iatridis JC: Polyphenol Metabolites Potentially Alleviate Painful Behavior Induced by Annular Injury – An In-vivo Rat Model, Transactions of the Orthopaedic Research Society, 2016, Poster # 1735.
  5. Cruz MA, Torre OM, Merrill RK, Illien-Junger S, Hecht AC, Iatridis JC: Genipin-crosslinked Fibrin has Potential for Use as a Cell Carrier for Annulus Fibrosus Repair, Transactions of the Orthopaedic Research Society, 2016, Poster # 0867.
  6. Kindschuh WF, Palacio-Mancheno P, Chen X, Iatridis JC, Illien-Jünger S: Sex-Dependent Effects of Dietary Advanced Glycation Endproducts on Vertebral Bone, Transactions of the Orthopaedic Research Society, 2016, Poster #  0908.
  7. Aly N, Palacio-Mancheno P, Ahmed F, Tadros M, Purmessur D, Iatridis: JC: Effects of Osmolarity on Nucleus Pulposus Matrix and Cellular Phenotype in a Mouse Whole IVD Organ Culture Model: Contributions of TRPV4 and Aquaporins, Transactions of the Orthopaedic Research Society, 2016, Poster.
  8. Tadros M, Palacio-Mancheno P, Ahmed F, Aly N, Purmessur D, Iatridis JC: Injury-related Changes to the Intervertebral Disc Phenotype are associated with Aquaporin Expression, Independent of TRPV4 in the Inner Annulus Fibrosus, Transactions of the Orthopaedic Research Society, 2016, Poster # 1749.
  9. Varma DM, Lin HA, Long RG, Hecht AC, Iatridis JC, Nicoll SB: In Situ Gelling Cellulosic Copolymer Hydrogels Restore Intervertebral Disc Height and Biomechanical Properties Post Nucleotomy, Transactions of the Orthopaedic Research Society, 2016, Poster # 0869.

 

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Dr. James Iatridis awarded 2015 Henry Farfan Award (NASS)

Iatridis

Please join us in congratulating Dr. James Iatridis on being awarded the prestigious Henry Farfan Award at the Annual North American Spine Society (NASS) Meeting in Chicago (October 16, 2015).  The Henry Farfan Award is awarded to those recognized for their outstanding contributions to spine related basic science research and is one of the four esteemed awards presented by NASS to recognize unique and outstanding contributions to the field of spine care and research.  He was nominated by Dr. Andrew Hecht of Mount Sinai and Dr. Christopher Bono of Brigham and Women’s Hospital.

“Dr. Iatridis is a world authority on numerous aspects of disc biology and mechanobiology.  Dr. Iatridis is at the forefront of research on annular repair, disk regeneration, pain biology, studies of the notochord and its function in healthy and degenerated discs.   Dr. Iatridis’s contributions to the field of disk biology are immeasurable, and he continues to run a continuously funded NIAH research lab. He has built a collaborative team of academic spine surgeons, post-doctoral fellows, medical students, orthopedic residents, who all continue to work with him on this ongoing research.   His ability to solve basic science problems and never lose sight of their translational applications is both inspiring and remarkable.   His post-doctoral fellows continue to be sought after candidates all over the country for numerous spine research positions and major academic medical centers.    Dr. Iatridis has an extensive publication history with over 200 publications, peer reviewed, in the areas of disc biology, disk mechanobiology, annular repair, disc mechanics.  Dr. Iatridis continues to be a leader in the field of disc mechanobiology, annular repair and intervertebral disc regeneration for years to come.”

Nominated by Andrew Hecht, MD [Associate Chief of Spine Surgery for the Mount Sinai Health System and Chief of Spine Surgery at the Mount Sinai Hospital]

“Dr.Iatridis has been extremely forward thinking and productive in his basic science research of disc biomechanics and biochemistry. His work is in many respects leading the field, combining the two sub disciplines of basic science in order to lead disc repair.”

Nominated by Christopher Bono, MD  [Associate Professor of Orthopedic Surgery at Harvard Medical School and Chief of the Orthopedic Spine Service at Brigham and Women’s Hospital (BWH)]

https://www.spine.org/WhoWeAre/GrantsAwards/RecognitionAwards.aspx

http://www.nassdailynews.org/2015-nass-recognition-awards/

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AO Visit to Mount Sinai

AO FAll 2015 visit_1

The Annulus Fibrosus Rupture (AFR) Consortium of the AO Foundation visited the ORL on September 16, 2015. The AFR consortium participated in research collaboration discussions and finished the day with a visit to the Cooper Hewitt, Smithsonian Design Museum.  The AFR is an international consortium with its epicenter at the AO Research Institute in Davos, Switzerland. The AFR consortium is committed to developing novel treatments to promote annulus re pair.