ACTIVE  

• NIH R01     HL139963  (Ishikawa)              12/15/2017 – 11/30/2026         Percutaneous Left Ventricular Unloading for Cardiogenic Shock: Beyond Acute Hemodynamic Support  (renewed)
• NIH R01    HL173593    (Ishikawa)             04/02/2024 – 01/31/2029       Cardiac AAV gene delivery for clinical translation
• Abiomed   Inc.        (Ishikawa)                       03/01/2016 – 1/18/2026         Improving the gene transduction efficacy of intracoronary delivery using an Impella
• APT Therapeutics (Ishikawa)                       01/01/2024- 04/30/2026        Multi-functional Antithrombotic Therapy for Coronary Microvascular Obstruction (SBIR)
• NIH  R01HL148786 (Sahoo)                        07/01/2019 – 06/30/2025       AAV-Exosomes: Escaping Neutralizing Antibody and Enhancing Delivery  (Co-I)
• NIH R61 HL163755 (Benza)                         09/01/2023 – 08/31/2026     The Development of a Biatrial Catheter for a Cardiopulmonary Support System in Pulmonary Arterial Hypertension (Co-I)
• Cardiac RSK3 inhibitors (Ishikawa)            06/27/2023 – 07/31/2025        Targeting of mAKAP Signalosomes in a pig model of myocardial infarction (SBIR)
• NIH S10 OD034330 (Ishikawa)                   04/01/2023 – 03/302028         Animal cathlab C-arm
• NIH NHLBI GTRP RSA 2035   (Ishikawa)                                                         Preclinical Vector Production “Improving Cardiac AAV Gene Transduction Using Intracoronary Delivery”

Completed/Ended

• Abiomed Inc        (Ishikawa)                         05/18/2022 – 06/30/2024       Combination of LV mechanical unloading and hypothermia for infarct size reduction
• Nuevocor   (Ishikawa)                                     08/01/2022 – 07/31/2023       Nuevocor-Sinai AAV gene therapy project: Clinically applicable AAV delivery methods for the heart
• NIH/NHLBI   1R01HL130423-01 (Ishikawa/Kovacic)         01/25/2016 – 12/31/2021         Toward Therapeutic Manipulation of Endothelial to Mesenchymal Transition.          Role (Co-PI)
• NIH/NHLBI  1R01HL135093 (Fish/Kovacic)    12/01/2016 – 11/30/2021           Therapeutic Mechanisms of Cardiac Progenitors in Ischemic Cardiomyopathy       Role (Co-I)
• AHA-SDG      17SDG33410873     (Ishikawa)    01/01/2017 – 12/31/2019            Mechanistic and Therapeutic Roles of miRNAs in Left Ventricular Remodeling and Heart Failure        Role (PI)
• NIH       R01HL131404 (Hajjar/Weber)               07/01/2016 – 06/30/2020          Anti-AAV Antibodies as an Obstacle to Cardiac AAV Gene Therapy       Role (Co-I)
• Cardiac RSK3 Inhibitors, LLC (Fish)                    02/06/2019 – 02/05/2020         Gene Therapy for Cardiac Remodeling
• T32 Research Fellowship (Mazurek)                  09/22/2020 – 09/21/2021
• Cardiac RSK3 inhibitors (Ishikawa)             9/30/2021-9/29/2022             AAV-RBD gene therapy in a pig model of myocardial infarction (PI)
• T32 Research Fellowship (Marvopoulos)         06/28/2021 – 06/27/2024
• ACURE Research Fellowship Grant (Sakata)  07/01/2021 – 06/30/2023