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Mount Sinai Center for Eosinophilic Disorders (MSCED)

About Us

The Mount Sinai Center for Eosinophilic Disorders (MSCED) is a comprehensive center that focuses on the diagnosis, treatment, and research of eosinophilic gastrointestinal disorders (EGIDs), including eosinophilic esophagitis (EoE), eosinophilic gastritis (EG), eosinophilic gastroenteritis (EGE), eosinophilic enteritis (EEnt) and eosinophilic colitis (EC). EGIDs are chronic inflammatory diseases of various parts of the gut, where one type of white blood cells, eosinophils, infiltrate the inner lining along with other immune cells, causing symptoms.

EGIDs affect both children and adults. Symptoms of EoE include difficulty swallowing foods and history of food getting stuck in the esophagus, but at times can be non-specific such as abdominal pain, gastroesophageal reflux symptoms and vomiting, leading to misdiagnosis as acid-induced gastroesophageal reflux disease. Patients with EGIDs lower down in the gut, beyond the esophagus, present with symptoms related to the organ affected. Examples include stomach pain and vomiting in patients with EG and stomach pain, vomiting and diarrhea in patients with EGE and EEnt. Diarrhea and blood in the stools can also occur in EC. Since these symptoms can occur in other gastrointestinal diseases, patients with EGIDs are at times misdiagnosed as having other gastrointestinal diseases as well. Children with EGIDs can suffer from failure to thrive, which is fortunately reversible with proper treatment of the underlying disease.

At the MSCED, we believe that patients with EGIDs have specific needs that are best treated by a team approach to management. Working closely together, our team of specialists will help the patient and family determine a diagnosis and set up a treatment plan which can include special diets, medications, and counseling. Our specialists include a gastroenterologist, allergists, pathologists, and a nutritionist. The center also takes part in the Jaffe Food Allergy Institute EMPOWER program, which offers children and their families’ consultations with a psychiatrist to help manage behavioral and emotional issues associated with EGIDs. Patients with EGIDs also have access to the MSCED support group and other educational activities at the Center.

Since EGIDs are newly recognized diseases, there is not a lot of information as to what causes them. MSCED’s director, Dr. Mirna Chehade, MD, MPH, is one of the leading researchers of eosinophilic gastrointestinal disorders publishing a number of papers and spearheading a number of research projects to further understand how these diseases occur and explore novel therapies for EGIDs.

Clinical focus:

  • Eosinophilic esophagitis
  • Eosinophilic gastritis
  • Eosinophilic gastroenteritis
  • Eosinophilic enteritis
  • Eosinophilic colitis
  • Food protein induced enterocolitis syndrome
  • Gastrointestinal food allergy