Millar Lab Research Publications

Zhu X, Xu M, Millar SE

 HDAC1/2 and HDAC3 play distinct roles in controlling adult Meibomian gland homeostasis

Pubmed, April 2024 pdf

Zhu X, Xu M, Senoo M, Millar SE, Ma G

Wnt/β-Catenin Signaling controls mouse eyelid growth by mediating epithelial-mesenchymal interactions

Pubmed, July 2023 pdf

Sun Q, Lee W, Hu H, Ogawa T, De Leon S, Katehis I, Lim CH, Takeo M, Cammer M, Taketo MM, Gay DL, Millar SE, Ito M

Dedifferentiation maintains melanocyte stem cell in a dynamic niche.

Pubmed, April 2023 pdf

 Zhu X, Xu M, Leu NA, Morrisey EE, Millar SE

 FRIZZLED 2 regulates limb development by mediating both β-catenin-dependent and independent Wnt signaling pathways

 Pubmed, March 2023 pdf

Tang AT, Buchholz DW, Szigety KM, Imbiakha B, Gao S, Frankfurter M, Wang M, Yang J, Hewins P, Mericko-Ishizuka P, Leu NA, Sterling S, Monreal IA, Sahler J, August A, Zhu X, Jurado KA, Xu M, Morrisey EE, Millar SE, Aguilar HC, Kahn ML

Cell-autonomous requirement for ACE2 cross organs in lethal mouse SARS-CoV-2 infection

Plos Biology, February 2023 pdf

Zhu X, Leboeuf M, Liu F, Grachtchouk M, Seykora JT, Morrisey EE, Dlugosz AA, Millar SE.

HDAC1/2 Control Proliferation and Survival in Adult Epidermis and Pre‒Basal Cell Carcinoma through p16 and p53

Journal of Investigative Dermatology, January 2022 pdf

Szigety KM, Liu F, Yuan CY, Moran DJ, Horrell J, Gochnauer HR, Cohen RN, Katz JP, Kaestner KH, Seykora JT, Tobias JW, Lazar MA, Xu M, Millar SE.

HDAC3 ensures stepwise epidermal stratification via NCoR/SMRT-reliant mechanisms independent of its histone deacetylase activity

Genes Dev, April 2020 pdf

Song Y, Boncompagni AC, Kim SS, Gochnauer HR, Zhang Y, Loots GG, Wu D, Li Y, Xu M, Millar SE.

Regional Control of Hairless versus Hair-Bearing Skin by Dkk2

Cell Reports, December 2018 pdf

Gaillard D, Bowles SG, Salcedo E, Xu M, Millar SE, Barlow LA.

β-catenin is required for taste bud cell renewal and behavioral taste perception in adult mice

PLoS Genetics, August 2017 pdf

Xu M, Horrell J, Snitow M, Cui J, Gochnauer H, Syrett CM, Kallish S, Seykora JT, Liu F, Gaillard D, Katz JP, Kaestner KH, Levin B, Mansfield C, Douglas JE, Cowart BJ, Tordoff M, Liu F, Zhu X, Barlow LA, Rubin AI, McGrath JA, Morrisey EE, Chu EY, Millar SE.

WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation

Nature Communications, June 2017 pdf

Gaillard D, Xu M, Liu F, Millar SE, Barlow LA.

β-Catenin Signaling Biases Multipotent Lingual Epithelial Progenitors to Differentiate and Acquire Specific Taste Cell Fates

PLoS Genetics, May 2015 pdf

Choi YS, Zhang Y, Xu M, Yang Y, Ito M, Peng T, Cui Z, Nagy A, Hadjantonakis AK, Lang RA, Cotsarelis G, Andl T, Morrisey EE, Millar SE.

Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis

Cell Stem Cell, December 2013 pdf

Takeda N, Jain R, Leboeuf MR, Padmanabhan A, Wang Q, Li L, Lu MM, Millar SE, Epstein JA.

Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells

Development, April 2013 pdf

Teta M, Choi YS, Okegbe T, Wong G, Tam OH, Chong MM, Seykora JT, Nagy A, Littman DR, Andl T, Millar SE.

Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin

Development, April 2012 pdf

LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE.

Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells

Developmental Cell, December 2010 pdf

Liu F, Dangaria S, Andl T, Zhang Y, Wright AC, Damek-Poprawa M, Piccolo S, Nagy A, Taketo MM, Diekwisch TG, Akintoye SO, Millar SE.

β-Catenin initiates tooth neogenesis in adult rodent incisors

Journal of Dental Research, September 2010 pdf

Zhang Y, Tomann P, Andl T, Gallant NM, Huelsken J, Jerchow B, Birchmeier W, Paus R, Piccolo S, Mikkola ML, Morrisey EE, Overbeek PA, Scheidereit C, Millar SE, Schmidt-Ullrich R.

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/β-catenin signaling pathways in hair follicle induction

Developmental Cell, July 2009 pdf

Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA.

Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/β-catenin signaling

Nature Genetics, September 2008 pdf

Zhang Y, Andl T, Yang SH, Teta M, Liu F, Seykora JT, Tobias JW, Piccolo S, Schmidt-Ullrich R, Nagy A, Taketo MM, Dlugosz AA, Millar SE.

Activation of β-catenin signaling programs embryonic epidermis to hair follicle fate

Development, June 2008 pdf

Liu F, Chu EY, Watt B, Zhang Y, Gallant NM, Andl T, Yang SH, Lu MM, Piccolo S, Schmidt-Ullrich R, Taketo MM, Morrisey EE, Atit R, Dlugosz AA, Millar SE.

Wnt/β-catenin signaling directs multiple stages of tooth morphogenesis

Developmental Biology, January 2008 pdf

Liu F, Thirumangalathu S, Gallant NM, Yang SH, Stoick-Cooper CL, Reddy ST, Andl T, Taketo MM, Dlugosz AA, Moon RT, Barlow LA, Millar SE.

Wnt-β-catenin signaling initiates taste papilla development

Nature Genetics, January 2007 pdf

Andl T, Murchison EP, Liu F, Zhang Y, Yunta-Gonzalez M, Tobias JW, Andl CD, Seykora JT, Hannon GJ, Millar SE.

The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles

Current Biology, May 2006 pdf

Chu EY, Hens J, Andl T, Kairo A, Yamaguchi TP, Brisken C, Glick A, Wysolmerski JJ, Millar SE.

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis

Development, October 2004 pdf

Reddy ST, Andl T, Lu MM, Morrisey EE, Millar SE.

Expression of Frizzled genes in developing and postnatal hair follicles

Journal of Investigative Dermatology, August 2004 pdf

Andl T, Ahn K, Kairo A, Chu EY, Wine-Lee L, Reddy ST, Croft NJ, Cebra-Thomas JA, Metzger D, Chambon P, Lyons KM, Mishina Y, Seykora JT, Crenshaw EB 3rd, Millar SE.

Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development

Development, May 2004 pdf

Millar SE, Koyama E, Reddy ST, Andl T, Gaddapara T, Piddington R, Gibson CW.

Over- and ectopic expression of Wnt3 causes progressive loss of ameloblasts in postnatal mouse incisor teeth

Connective Tissue Research, January 2003 pdf

Andl T, Reddy ST, Gaddapara T, Millar SE.

WNT signals are required for the initiation of hair follicle development

Developmental Cell, May 2002 pdf

Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, Millar SE.

Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis

Mechanisms of Development, September 2001 pdf

Millar Lab Reviews, Previews and Perspectives

Millar SE

20 years of Developmental Cell: Looking back

Developmental Cell, December 2021 pdf

Millar SE.

How a Bird Gets Its Feathers: Insights from Chromatin Looping

Developmental Cell, June 2020 pdf

Millar SE.

A pulpy story

Nature Materials, June 2019 pdf

Millar SE.

Revitalizing Aging Skin through Diet

Cell, November 2018 pdf

Millar SE.

Hox in the Niche Controls Hairy-geneity

Cell Stem Cell, October 2018 pdf

Millar SE.

Secrets of the Hair Follicle: Now on Your iPhone

Developmental Cell, September 2015 pdf

Millar SE.

Committing to a hairy fate: epigenetic regulation of hair follicle stem cells

Cell Stem Cell, September 2011 pdf

Liu F, Millar SE.

Wnt/β-catenin signaling in oral tissue development and disease

Journal of Dental Research, April 2010 pdf

Millar SE.

Cell biology: The not-so-odd couple

Nature, July 2009 pdf

Stark J, Andl T, Millar SE.

Hairy math: insights into hair-follicle spacing and orientation

Cell, January 2007 pdf

Mikkola ML, Millar SE.

The mammary bud as a skin appendage: unique and shared aspects of development

Journal of Mammary Gland Biology and Neoplasia, October 2006 pdf

Millar SE.

Smad7: licensed to kill β-catenin

Developmental Cell, September 2006 pdf

Millar SE.

An ideal society? Neighbors of diverse origins interact to create and maintain complex mini-organs in the skin

PLoS Biology, November 2005 pdf

Millar SE.

WNTs: multiple genes, multiple functions

Journal of Investigative Dermatology, January 2003 pdf

Millar SE.

Molecular mechanisms regulating hair follicle development

Journal of Investigative Dermatology, February 2002 pdf

Cotsarelis G, Millar SE.

Towards a molecular understanding of hair loss and its treatment

Trends in Molecular Medicine, July 2001 pdf