PROTACs

Our Novel Degraders Targeting Oncogenic Proteins:

MS4077 & MS4078: ALK degrader (PMID: 29627725)

MS432: MEK1/2 degrader (PMID:31730343)

MS1943: EZH2 degrader (PMID:31819273)

MS39: EGFR degrader (PMID: 31895569)

MS154: EGFR degrader (PMID: 31895569)

Opto-pomalidomide: light-induced pomalidomide (PMID: 32128407)

Opto-dBET1: light-induced BET degrader (PMID: 32128407)

Opto-dALK: light-induced ALK degrader (PMID: 32128407)