Publications

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Selected Publications

  1. Chehade M. Eosinophilic gastrointestinal disorders: The journey to diagnosis remains arduous. Ann Allergy Asthma Immunol [Epub ahead of print].
  2. Chehade M, Nowak-Wegrzyn A. The asymptomatic patient with eosinophilic esophagitis: To treat or not to treat? Ann Allergy Asthma Immunol 2019;122;550-1
  3. Chehade M, Meyer R, Beauregard A. Feeding difficulties in children with non-IgE-mediated food allergic gastrointestinal disorders. Ann Allergy Asthma Immunol 2019;122:603-9.
  4. Chehade M. New diagnostic criteria for eosinophilic esophagitis: Will they influence our practice? Ann Allergy Asthma Immunol 2018;121:266-7.
  5. Chehade M. Eosinophilic esophagitis 25 years after its recognition: Where do we stand? Ann Allergy Asthma Immunol 2018;121:141-2.
  6. Dellon ES, Liacouras CA, Molina-Infante J, Furuta GT, Spergel JM, Zevit N, Spechler SJ, Attwood SE, Straumann A, Aceves SS, Alexander JA, Atkins D, Arva NC, Blanchard C, Bonis PA, Book WM, Capocelli KE, Chehade M, Cheng E, Collins MH, Davis CM, Dias JA, DiLorenzo C, Dohil R, Dupont C, Falk GW, Ferreira CT, Fox A, Gonsalves NP, Gupta SK, Katzka DA, Kinoshita Y, Menard-Katcher C, Kodroff E, Metx DC, Miehlke S, Muir AB, Mukkada VA, Murch S, Nurko S, Ohtsuka Y, Orel R, Papadopoulou A, Peterson KA, Philpott H, Putnam PE, Richter JE, Rosen R, Rothenberg ME, Schoepfer A, Scott MM, Shah N, Sheikh J, Souza RF, Strobel MJ, Talley NJ, Vaezi MF, Vandenplas Y, Vieira MC, Walker MM, Wechsler JB, Wershil BK, Wen T, Yang GY, Hirano I, Bredenoord AJ. Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. Gastroenterology 2018 [Epub ahead of print]
  7. Ferreira CT, Vieira MC, Furuta GT, Barros FCLF, Chehade M. Eosinophilic esophagitis- Where are we today? J Pediatr (Rio J) 2018 [Epub ahead of print]
  8. Ko E, Chehade M. Biological Therapies for Eosinophilic Esophagitis: Where Do We Stand? Clinical Reviews in Allergy & Immunology 2018 Jan 25 [Epub ahead of print].
  9. Gupta SK, Falk GW, Aceves SS, Chehade M, Collins MH, Dellon ES, Gonsalves N, Hirano I, Mukkuda VA, Peterson KA, Spergel J, Yang GY, Furuta GT, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Consortium for Eosinophilic Researchers (CEGIR): Advancing the Field of Eosinophilic GI Disorders Through Collaboration. Gastroenterology 2018 [Epub ahead of print]
  10. Chehade M, Jones SM, Pesek RD, Burks AW, Vickery BP, Wood RA, Leung DYM, Furuta GT, Fleischer DM, Henning AK, Dawson P, Lindblad RW, Sicherer SH, Abonia JP, Sherrill JD, Sampson HA, Rothenberg ME. Phenotypic Characterization of Eosinophilic Esophagitis in a Large Multi-Center Patient Population from the Consortium for Food Allergy Research. J Allergy Clin Immunol Pract 2018;6:1534-1544.
  11. Kottyan LC, Maddox A, Braxton JR, Stucke EM, Mukkada V, Putnam PE, Abonia JP, Chehade M, Wood RA, Pesek RD, Vickery BP, Furuta GT, Dawson P, Sampson HA, Martin LJ, Kelly JA, Kimberly RP, Sivils K, Gaffney PM, Kaufman K, Harley JB, Rothenberg ME. Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis. Genes Immun 2018 Jun 8 [Epub ahead of print]
  12. Zeng C, Vanoni S, Wu D, Caldwell JM, Wheeler JC, Arora K, Noah TK, Waggoner L, Besse JA, Yamani AN, Uddin J, Rochman M, Wen T, Chehade M, Collins MH, Mukkada VA, Putnam PE, Naren AP, Rothenberg ME, Hogan. Solute carrier family 9, subfamily A, member 3 (SLC9A3)/sodium-hydrogen exchanger member 3 (NHE3) dysregulation and dilated intercellular spaces in patients with eosinophilic esophagitis. J Allergy Clin Immunol 2018 May 4 [Epub ahead of print]
  13. Cheng K, Gupta SK, Kantor S, Kuhl JT, Aceves SS, Bonis PA, Capocelli KE, Carpenter C, Chehade M, Collins MH, Dellon ES, Falk GW, Gopal-Srivastava R, Gonsalves N, Hirano I, King EC, Leung J, Krischer JP, Mukkada VA, Schoepfer A, Spergel JM, Straumann A, Yang GY, Furuta GT, Rothenberg ME. Creating a multi-center rare disease consortium- the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Translational Science of Rare Diseases 2017;2:141-55
  14. Ho HE, Chehade M. Development of IgE-mediated immediate hypersensitivity to a previously tolerated food following its avoidance for eosinophilic gastrointestinal diseases. J Allergy Clin Immunol Pract 2017 [Epub ahead of print]
  15. Chehade M, Sher E. Medical Therapy versus Dietary Avoidance in Eosinophilic Esophagitis: Which Approach is Better? Allergy and Asthma Proceedings 2017;38:170-6.
  16. Kagalwalla AF, Wechsler JB, Amsden K, Schwartz S, Makhija M, Olive A, Davis CM, Manuel-Rubio M, Marcus S, Sulkowski K, Johnson K, Ross JN, Riffle ME, Groetch M, Melin-Aldana H, Schady D, Palac H, Kim, K-YA, Wershil BK, Collins MH, Chehade M. Efficacy of a 4-Food Elimination Diet for Children With Eosinophilic Esophagitis. Clin Gastroenterol Hepatol 2017;15:1698-1707.
  17. Riffle ME, Polydorides AD, Niakan J, Chehade M. Eosinophilic Esophagitis and Esophageal Granular Cell Tumor: An Unexpected Association. Am J Surg Pathol 2017;41:616-21.
  18. Groetch M, Venter C, Skypala I, Vlieg-Boerstra B, Grimshaw K, Durban R, Cassin A, Henry M, Kliewer K, Kabbash L, Atkins D, Nowak-Węgrzyn A, Holbreich M, Chehade M; on behalf of the Eosinophilic Gastrointestinal Disorders Committee of the American Academy of Allergy, Asthma and Immunology. Dietary Therapy and Nutrition Management of Eosinophilic Esophagitis:  a Work Group Report of the American Academy of Allergy, Asthma and Immunology. J Allergy Clin Immunology in Practice 2017;5:312-24.
  19. Nowak-Węgrzyn, A, Chehade M, Groetch M, Spergel JM, Wood RA, Allen K, Atkins D, Bahna S, Barad A, Berin C, Brown Whitehorn T, Burks AW, Caubet JC, Cianferoni A, Conte M, Davis C, Fiocchi A, Grimshaw K, Gupta R, Hofmeister B, Hwang JB, Katz Y, Konstantinou GN, Leonard, SA, Lightdale J, McGhee S, Mehr S, Miceli Sopo S, Monti G, Muraro A, Noel S, Nomura I, Noone S, Sampson HA, Schultz F, Sicherer SH, Thompson C, Turner PJ, Venter C, Westcott-Chavez A, Greenhawt M. International Consensus Guidelines for the Diagnosis and Management of Food Protein-Induced Enterocolitis Syndrome- Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma, and Immunology. J Allergy Clin Immunol (in press)
  20. Chehade M. Eosinophilic esophagitis: when to suspect it and how to diagnose it in children and adolescents. Revista Paulista de Pediatria 2016; 34: 395-6.
  21. Andreae DA, Hanna MG, Magid MS, Malerba S, Andreae MH, Bagiella E, Chehade M. Swallowed Fluticasone Propionate is an Effective Long-Term Maintenance Therapy for Children with Eosinophilic Esophagitis. Am J Gastroenterol 2016;111:1187-97.
  22. Moawad FJ, Dellon ES, Achem SR, Ljuldjuraj T, Green DJ, Maydonovitch CL, Brizuela DR, Gupta SK, Chehade M. Effects of Race and Sex on Features of Eosinophilic Esophagitis. Clin Gastroenterol Hepatol 2016: 14; 23-30.
  23. Moawad FJ, Cheng E, Schoepfer A, Al-Haddad S, Bellizzi AM, Dawson H, El-Zimaity H, Guindi M, Penagini R, Safrooneva E, Chehade M. Eosinophilic esophagitis: current perspectives from diagnosis to management. Ann N Y Acad Sci 2016; 1380: 204-17.
  24. Chehade M, Aceves SS, Furuta GT, Fleischer DM. Food Allergy and Eosinophilic Esophagitis: What Do We Do? J Allergy Clin Immunol in Practice 2015; 3: 25-32.
  25. Schoepfer AM, Straumann A, Panczak R, Coslovsky M, Kuehni CE, Maurer E, Haas NA, Romero Y, Hirano I, Alexander JA, Gonsalves N, Furuta GT, Dellon ES, Leung J, Collins MH, Bussmann C, Netzer P, Gupta SK, Aceves SS, Chehade M, Moawad FJ, Enders FT, Yost KJ, Taft TH, Kern E, Zwahlen M, Safroneeva E; International EEsAI Study Group. Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis. Gastroenterology 2014; 147: 1255-1266.
  26. Kottyan LC, Davis BP, Sherrill JD, Liu K, Rochman M, Kaufman K, Weirauch MT, Vaughn S, Lazaro S, Rupert A, Kahram M, Stucke EM, Kemme KA, Magnusen A, He H, Dexheimer P, Chehade M, Wood RA, Pesek RD, Vickery BP, Fleischer DM, Lindbad R, Sampson HA, Mukkada V, Putnam PE, Abonia JP, Martin LJ, Harley JB, Rothenberg ME. Identification of genome-wide susceptibility loci for eosinophilic esophagitis elucidates tissue-specificity of this allergic disease. Nature Genetics 2014; 46: 895-900.
  27. Ko HM, Morotti RA, Yershov O, Chehade M. ­­­Eosinophilic Gastritis in Children: Clinicopathological Correlation, Disease Course and Response to Therapy. American Journal of Gastroenterology 2014; 109: 1277-85.
  28. Chehade M, Lucendo AJ, Achem SR, Souza RF. Causes, evaluation, and consequences of eosinophilic esophagitis. Ann NY Acad Sci 2013; 1300: 110-8.
  29. Lieberman JA, Morotti RA, Konstantinou GN, Yershov O, Chehade M. Dietary therapy can reverse esophageal subepithelial fibrosis in patients with eosinophilic esophagitis: A historical cohort. Allergy 2012; 67: 1299-307.
  30. Lieberman JA, Chehade M. Eosinophilic esophagitis: Diagnosis and Management. Immunol Allergy Clin N Am 2012; 32: 67-81.
  31. Liacouras CA, Furuta GT, Hirano I, Atkins D, Attwood S, Bonis PA, Burks AW, Chehade M, Collins MH, Dellon ES, Dohil R, Falk GW, Gonsalves N, Gupta SK, Katzka DA, Lucendo AJ, Markowitz JE, Noel RJ, Odze RD, Putnam PE, Richter JE, Romero Y, Ruchelli E, Sampson HA, Schoepfer A, Shaheen NJ, Sicherer SH, Spechler S, Spergel JM, Straumann A, Wershil BK, Rothenberg ME, Aceves S. Eosinophilic esophagitis: Updated consensus recommendations for children and adults. J Allergy Clin Immunol 2011; 128: 3-20.
  32. Chehade M, Aceves SS. Food allergy and eosinophilic esophagitis. Curr Opin Allergy Clin Immunol 2010; 10: 231-7.
  33. Chehade M, Sampson HA. The role of lymphocytes in eosinophilic gastrointestinal disorders. Immunol Allergy Clin North Am 2009; 29: 149-58
  34. Chehade M, Sampson HA. Epidemiology and etiology of eosinophilic esophagitis. Gastrointest Endoscopy Clin N Am 2008; 18: 33-44.
  35. Chehade M. Translational research on the pathogenesis of eosinophilic esophagitis. Gastrointest Endoscopy Clin N Am 2008; 18: 145-56.
  36. Chehade M, Sampson HA, Morotti RA, Magid MS. Esophageal subepithelial fibrosis in children with eosinophilic esophagitis. J Pediatr Gastroenterol Nutr 2007; 45: 319-28.
  37. Chehade M, Sicherer SH, Magid MS, Rosenberg HK, Morotti RA. Multiple exudative ulcers and pseudopolyps in allergic eosinophilic gastroenteritis that responded to dietary therapy. J Pediatr Gastroenterol Nutr 2007; 45: 354-7.
  38. Li H, Chehade M, Liu W, Xiong H, Mayer L, Berin MC. Allergen-IgE complexes trigger CD23-dependent CCL20 release from human intestinal epithelial cells. Gastroenterology 2007; 133: 1905-15.
  39. Chehade M. IgE- and non-IgE-mediated food allergy- treatment in 2007. Curr Opin Allergy Clin Immunol 2007; 7: 264-8.
  40. Chehade M, Magid MS, Mofidi S, Nowak-Wegrzyn A, Sampson HA, Sicherer SH. Eosinophilic gastroenteritis with protein-losing enteropathy: Intestinal pathological characteristics, clinical course, and long-term follow-up. J Pediatr Gastroenterol Nutr 2006; 42: 516-21.
  41. Chehade M, Mayer L. Oral tolerance and its relation to food hypersensitivities. J Allergy Clin Immunol 2005; 115: 3-12.