HUANG LAB | COMPUTATIONAL OMICS

Team

Kuan-lin Huang, Ph.D.

Kuan-lin Huang, Ph.D.

Chief Beggar and Cheerleader (aka Principal Investigator)

I grew up on the other side of the globe in Taiwan. I earned my B.A. from Wesleyan University, CT with a High Honors dissertation in Molecular Biology & Biochemistry (yeast molecular genetics) and an Honors dissertation in Studio Art (conceptual installations). I then obtained my Ph.D. at Washington University in St. Louis, where I first conducted statistical genomics research of Alzheimer’s disease with Dr. Alison Goate and subsequently joined Dr. Li Ding’s lab to study cancer genomics and proteomics. I started the Computational Omics Lab at the Department of Genetics and Genomic Sciences and Center for Transformative Disease Modeling at Mount Sinai in October 2018, continuing to fight against human disease and against my insatiable craving for dark chocolates at work.

        Kuan’s YouTube Channel    

ScienceBroadcast.org: Share Your Science Through Video          

Abdulkadir Elmas, Ph.D.

Abdulkadir Elmas, Ph.D.

(aka Postdoctoral Fellow)

I earned my BS in Electrical Engineering (telecommunications) from Istanbul University, and obtained my PhD in Electrical Engineering from Columbia University in New York. In  Dr. Wang’s lab at Columbia I discovered the information science as an avenue for solving complex problems in biology and developed a passion for Bioinformatics leading to my dissertation on Signal Processing applications for analyzing genomic sequences and gene regulatory networks. I then joined Dr. Liu’s lab at Biodesign Institue in Arizona to study biomarker discovery by Machine Learning for autoimmune diseases. Now I pursue the study of immuno-genomics and proteomics in cancer with Dr. Huang in the Computational Omics lab at Mount Sinai.
Zishan Wang, Ph.D.

Zishan Wang, Ph.D.

Stay hungry and stay foolish (aka postdoctoral fellow)

Born and grew up in China, once a serious illness motivated me to enter Harbin Medical University, where I earned my B.S. of bioinformatics and Ph.D. of biological engineering. During Ph.D. stage, I used bioinformatics method to explore the molecular mechanisms controlling regulation of gene expression in human cancers, mainly including transcription factors, epigenetics, cancer genetics, biology network and computational system biology. Now I pursue the exploration of computational omics of cancer at Mount Sinai, wishing to promote the treatment of cancer. In my spare time, I like running and playing table tennis.

Tomi Jun, MD

Tomi Jun, MD

24th grade and counting (aka Hematology Oncology Fellow)

I earned by BA in Biology from Dartmouth College, my MD from Harvard Medical School, and completed residency in internal medicine at Stanford University Medical Center. Along the way I’ve worked on iron homeostasis in plants, synthetic gene circuits in E. coli, and clinical outcomes and biomarkers for hepatocellular carcinoma. I’m currently a fellow in hematology and oncology, with an interest in using computational methods to understand and improve immunotherapy in solid tumors, especially hepatocellular carcinoma.

Teja Ganta, MD

Teja Ganta, MD

On-Call Pizza Critic (aka Hematology/Oncology Fellow)

Growing up in the quiet suburbs of New Jersey, I always knew I would eventually find my way to New York City. In the meantime, I earned a BS in Biochemistry at Boston College and an MD at Rutgers New Jersey Medical School, after which I completed my residency in internal medicine at Boston University Medical Center. My work is in clinical cancer informatics and applied machine learning to both build and deploy predictive models or clinical decision support tools into electronic health records to optimize cancer patient care. As a clinical fellow at The Mount Sinai Hospital, I hope to focus my clinical expertise to become a leader in the care of patients with lung cancers.

Will Lee

Will Lee

Ancient literature enthusiast (aka MSBDS student)

Born and raised in North Jersey, I graduated from Brown University in 2019 with a degree in Immunobiology. At Brown I worked to characterize the effect of secreted glycoprotein chitinase 3-like-1 on the expression of immune checkpoint proteins in murine primary lung cancer and pulmonary metastasis models. I am passionate about cancer research and hope to advance immunotherapy using data-driven approaches.

Miriam Saffern

Miriam Saffern

Life-long learner (aka PhD rotation student)

My journey to Sinai began with a trek from my hometown in New Jersey to midtown Manhattan to study biochemistry and math at Stern College for Women. My interest in the integration of science and math led me to then migrate up to Morningside Heights to complete a joint BA/BS degree through the 3-2 combined plan in engineering at Columbia University, where I studied biomedical engineering. During my undergraduate years, I conducted research in immunology at MSKCC and in biomedical engineering at Columbia. Through these experiences, as well as through seminal biology and computer science courses, I developed an interest in immuno-oncology and bioinformatics and an eagerness to join the scientific community and fuel my love of learning. Currently, I am a first year PhD student in the Graduate School of Biomedical Sciences at Icahn School of Medicine at Mount Sinai, ready to tackle scientific problems with the end goal of transforming patient care. Some of my hobbies include browsing book stores, eating froyo, swimming, and a recent fetish for hand lettering and building Ikea furniture.

Serena Tharakan

Serena Tharakan

Principal Baker (aka MD Candidate)

Serena received her B.S. in Molecular, Cellular, and Developmental Biology from Yale University in 2018, graduating Phi Beta Kappa. There, she worked in the lab of Dr. Lloyd Cantley studying the immune response to acute kidney disease, for which she was awarded the Senior Prize for Excellence in Research. She is currently in her first year of medical school at the Icahn School of Medicine at Mount Sinai and is interested in the field of hematology/oncology.

Jack Rutland

Jack Rutland

(aka MD candidate)

Jack Rutland is a first year medical student at the Icahn School of Medicine at Mount Sinai. Jack is working in the neurosurgery department investigating molecular genetic markers of disease features in meningiomas. Jack’s research also includes identifying radiological biomarkers of visual function in patients with pituitary adenoma. 

Alexandra Capellini

Alexandra Capellini

Always in the mood for coffee and ice cream (aka MD/MSCR Candidate)

Originally from the far away land of Brooklyn, I moved down to Baltimore to explore life in Charm City as an undergraduate at Johns Hopkins University. I earned a Bachelor of Arts in Public Health Studies. During my time at Hopkins, I was involved in ethnographic extreme poverty and child health research as well as systems science modeling research exploring evaluation metrics for USAID. I was also involved in clinical/translational research exploring the use of machine learning algorithms to develop multimodal MRI models for prediction of mutation status in high-grade gliomas. I am currently in my first year of medical school at the Icahn School of Medicine at Mount Sinai. I am interested in pediatric oncology/hematology, predictive modeling of patient risk, cancer immunotherapy and clinical trial analyses. Outside of Sinai, I enjoy swimming, skiing, dancing, traveling, being outdoors and playing clarinet in a local orchestra.

Suraj Jaladanki

Suraj Jaladanki

Principal Optimist (aka MD Candidate)

Suraj received his B.S. in Biology with a specialization in Cell Biology & Genetics and Computer Science minor from the University of Maryland, College Park (UMD). He used transcriptomic data (RNA-Seq) to study differential gene expression of the Malaclemys terrapin (the diamondback terrapin), the mascot of the institution. He also has several years of wet-lab experience after spending summers analyzing gut epithelial barrier integrity at the molecular level at the University of Maryland School of Medicine (UMDSOM). He is currently a first year medical student at the Icahn School of Medicine at Mount Sinai (ISMMS). 

Daniel Fulop

Daniel Fulop

Mountain Bagger (aka MD Candidate)

My name is Dan Fulop. I am a first-year medical student at Mount Sinai and will be completing an MD/MSCR with a focus on translational oncology as a part of the PORTAL program.

Shoshana Rosenzweig

Shoshana Rosenzweig

Aspiring marathoner (aka MD candidate)

I am currently a first year medical student at the Icahn School of Medicine at Mount Sinai, interested in pediatric oncology and cancer genomics. I received a BA in Computational Biology from Brown University in 2019, earning Sigma Xi and honors. At Brown, I was involved in research that used RNA-seq analysis to study the effect of VPA on fetal development and the development of autism spectrum disorder.

Makda Zewde

Makda Zewde

Professional snacker (aka MD candidate)

I received my B.S. in Biology from Ithaca College in 2015 and my M.S. in Biostatistics from Northwestern University in 2019. In between, I worked for three years in the Nakamura lab at the University of Chicago, characterizing the T-cell receptor repertoire and immune microenvironment in various cancers. I then spent a year in the Chevrier lab at the same institution, developing a T-cell receptor sequencing protocol to characterize immune responses to viral infection in mice. I am currently a first-year medical student at the Icahn School of Medicine at Mount Sinai and I am interested in the field of cancer immunology.

Gabriel Santos Malave

Gabriel Santos Malave

Dog Aficionado (aka MD candidate)

I was born and raised in San Juan, Puerto Rico. I graduated from Georgetown University in 2019 where I earned a Bachelor of Arts in English and also minored in cognitive science. At Georgetown, I worked in the Developmental Cognitive Neuroscience Laboratory where I worked on research examining the structural and functional changes in the brain as a result of pediatric bariatric surgery. I also conducted research in the fields of global health and chronic critical illness. I am currently a first-year medical student at the Icahn School of Medicine at Mount Sinai.