The Bhardwaj Lab focuses on the study of dendritic cells, which serve a crucial function as sentinels of the immune system. They are potent antigen-presenting cells, which integrate microbe sensing, antigen display, and context-dependent instruction to T cells, to direct the appropriate type of immune response. The Bhardwaj Lab focuses on combining fundamental research in dendritic cell biology with innovative translational and clinical approaches. We are investigating specialized cytokine secretion, antigen presentation, T cell skewing, interactions with NK cells, and optimal methods of antigen delivery for vaccines using dendritic cells, in HIV and cancer.
- ACIR featured article – December 2020