Our Giotto Suite paper has just been published in Nature Methods! In this paper, we showcased its power as a multiscale, extensible, and technology-agnostic ecosystem for spatial multi-omics data analysis. Key advances include: multiscale analysis, cross-technology integration, multi-omics integration, scalability, and interoperability. This is the result of a multi-year fantastic collaboration between the Guo-Cheng Yuan and Ruben Dries Labs. Congratulations to the co-first authors: Jiaji George Chen, Joselyn C. Chávez-Fuentes, and other members in the Yuan and Dries labs for their terrific contribution! More background information can be found in the accompanied Mount Sinai news release article.