Welcome to the Pei Wang Lab


We are interested in developing statistical and computational methods to address scientific questions based on data from high throughput biology/genetics experiments.  The ultimate goal is to enhance our understanding of cell activities and disease initiation/progression to a system level by integrating information from diverse biological sources (genetics/genomics, proteomics, and phenotypes).
Towards this goal, efforts have been made to properly model each individual type of data and to effciently characterize interactions among different biology molecules. These efforts all borrow strength from and contribute to the developments of high dimensional inference.

 


Proteogenomic analysis
Proteogenomic analysis of pediatric and AYA high-grade glioma reveals age-dependent biology, female-male differences, and kinase targets

Learning directed acyclic graphs
Learning directed acyclic graphs for ligands and receptors based on spatially resolved transcriptomic data of ovarian cancer

Proteogenomic analysis
Pan-cancer proteogenomics characterization of tumor immunity

RECCIPE
RECCIPE: A new framework assessing localized cell-cell interaction on gene expression in multicellular ST data