Dr. Miller’s research concentrates on the mechanisms for the onset of asthma. One large research focus involves establishing and studying a birth cohort from Northern Manhattan (Columbia Center for Children’s Environmental Health), determining the importance of environmental allergens, traffic-related pollutants, and phthalate and bisphenol A exposure to the onset of allergies, asthma and allergic immune responses. A major emphasis is on the role of prenatal and early postnatal exposure on later pediatric and adolescent asthma risk.
Additional areas of research include identifying novel genetic by environment interactions important to the onset of asthma. She also has established several mouse models examining the importance of prenatal and postnatal environmental exposures on risk for asthma and other complex diseases. More recent initiatives have been to build a program in environmental epigenetics and asthma by studying DNA methylation in cell, mouse and human systems for which she is now internationally recognized. Read more.