Welcome to the McAlpine Lab!

Immune cells are protagonists in the physiology and pathology of all organs and tissues. With the ability to travel and communicate over long distances, immune cells can link seemingly unconnected systems. The overarching theme of our research program is to investigate neuro-immune networks, immune cell function, and inter-organ communication in cardiovascular and Alzheimer’s disease.

We are a multidisciplinary and inclusive research team located in the Cardiovascular Research Institute at the Icahn School of Medicine at Mount Sinai in New York City.

We are also active members of many other institutes and centers at ISMMS, including the Friedman Brain Institute, the Loeb Center for Alzheimer’s Disease, and the Brain and Body Research Center.