Immune cells are protagonists in the physiology and pathology of all organs and tissues. With the ability to travel and communicate over long distances, immune cells can link distal systems and influence effector organ function and health. The overarching theme of our research program is to investigate neuro-immune networks, immune cell function, and inter-organ communication in cardiovascular and neurodegenerative diseases. We have a specific focus on how sleep mediates hematopoiesis and myeloid cell biology in chronic age-related pathologies.

We are a multidisciplinary and inclusive research team located in the Cardiovascular Research Institute at the Icahn School of Medicine at Mount Sinai in New York City.

We are also active members of many other institutes and centers at ISMMS, including the Friedman Brain Institute, the Loeb Center for Alzheimer’s Disease, and the Brain and Body Research Center.