Amir Horowitz, PhD

Principal Investigator
Assistant Professor of Oncological Sciences
Precision Immunology Institute/ Tisch Cancer Institute

Amir Horowitz, PhD is an Assistant Professor of Oncological Sciences and a member of the Precision Immunology Institute and the Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

Dr. Horowitz’s work has contributed to developing an understanding of adaptive NK cells and their roles in cancers, microbial infections,  and following vaccination and transplantation. He pioneered the first studies of human NK cells by mass cytometry (CyTOFTM) and demonstrated an enormous breadth of phenotypic diversity and functions associated with specific HLA class I and KIR backgrounds. This research has led to the identification and characterization of numerous NK cell subset populations with unique activity and immunotherapeutic potential. This work and related future research will address his long-term career goal of understanding how immunogenetic variation governs the development and education of NK cells and their ability to function within dynamic environments.