Postdoctoral Fellow
rodrigo.canas.arranz@mssm.edu

Research Interests
Innate immune responses are the first barrier of defense against viral infections. The induction of type I and III IFN is a critical step to provide an antiviral state and limit viral replication in the host. My work focuses on the host immune response to viral infections. Specifically, type I and III IFN responses using  in vitro and in vivo models as well as the role of certain IFN-stimulated genes to clear the infection against several viruses, including Influenza virus, SARS-CoV-2 or West Nile Virus. Understanding the mechanisms underlying these virus-host interactions, would allow identifying new antiviral targets and the development of vaccines

Notable Publications
Canas-Arranz, R., P. de Leon, M. Forner, S. Defaus, M. J. Bustos, E. Torres, D. Andreu, E. Blanco, and F. Sobrino. 2020. ‘Immunogenicity of a Dendrimer B2T Peptide Harboring a T-Cell Epitope From FMDV Non-structural Protein 3D‘, Front Vet Sci, 7: 498.

Canas-Arranz, R., M. Forner, S. Defaus, P. de Leon, M. J. Bustos, E. Torres, F. Sobrino, D. Andreu, and E. Blanco. 2020. ‘A Single Dose of Dendrimer B2T Peptide Vaccine Partially Protects
Pigs against Foot-and-Mouth Disease Virus Infection’, Vaccines (Basel), 8.

Canas-Arranz, R., M. Forner, S. Defaus, M. Rodriguez-Pulido, P. de Leon, E. Torres, M. J. Bustos, B. Borrego, M. Saiz, E. Blanco, D. Andreu, and F. Sobrino. 2020. ‘A bivalent B-cell epitope dendrimer peptide can confer long-lasting immunity in swine against foot-and-mouth disease‘, Transbound Emerg Dis, 67: 1614-22.

de Leon, P., R. Canas-Arranz, S. Defaus, E. Torres, M. Forner, M. J. Bustos, C. Revilla, J. Dominguez, D. Andreu, E. Blanco, and F. Sobrino. 2020. ‘Swine T-Cells and Specific Antibodies Evoked by Peptide Dendrimers Displaying Different FMDV T-Cell Epitopes‘, Front Immunol, 11: 621537.

de Leon, P., R. Canas-Arranz, Y. Saez, M. Forner, S. Defaus, D. Cuadra, M. J. Bustos, E. Torres, D. Andreu, E. Blanco, F. Sobrino, and S. E. Hammer. 2020. ‘Association of Porcine Swine Leukocyte Antigen (SLA) Haplotypes with B- and T-Cell Immune Response to Foot-and-Mouth Disease Virus (FMDV) Peptides‘, Vaccines (Basel), 8.