Sleep & Healthy Aging Study
Exploring the associations between sleep, REM sleep behavior disorder, and neurodegenerative disorders
The SHAS study investigates how sleep disturbances, including REM sleep behavior disorder, may reveal the earliest signs of neurodegenerative diseases such as Parkinson’s disease and dementia with Lewy bodies. By integrating wearable sleep data, questionnaires, in-lab sleep testing, clinical assessments, and blood-based biomarkers, SHAS aims to develop predictive models that enable earlier detection of neurodegeneration, when intervention may be most effective.
If you are interested in participating in this study, please contact study coordinator Katelyn Ryu at kanghyun.ryu@mountsinai.org or 917-946-3862
DREAMING Study
Exploring the Gut–Brain Connection in REM Sleep Behavior Disorder and Parkinson’s Disease
The DREAMING Study investigates how changes in the gut microbiome and markers of inflammation may be linked to REM sleep behavior disorder and the future development of Parkinson’s disease. By analyzing biomarkers found in stool, blood, and urine samples, as well as genetic inflammatory profiles and gut microbiota composition, the study aims to identify non-invasive biomarkers that may help predict conversion to Parkinson’s disease in individuals with RBD.
If you are interested in participating in this study, please contact study coordinator Anketse Debebe at anketse.debebe@mssm.edu