David was appointed as an Assistant Professor at the Icahn School of Medicine in December 2013. He was born in Barcelona (Catalonia, Spain). He obtained his medical degree from Universitat Autònoma de Barcelona and completed residency training in Pathology (with a special focus in Hematopathology) at the Hospital del Mar/IMAS, under the supervision of Prof. Sergi Serrano-Figueras. He obtained his PhD from Universitat Pompeu Fabra in Barcelona, studying the regulation of the Snail transcription factor during cancer invasion and metastasis with Antonio Garcia de Herreros at the Institut Hospital del Mar d’Investigacions Mèdiques (IMIM). Then he joined the laboratory of Riccardo Dalla-Favera at Columbia University as a postdoctoral fellow. There he studied and dissected the role of the proto-oncogene c-MYC during normal B cell responses and B cell lymphomagenesis. He described a novel role for MYC in the control of DNA replication and identified MYC as a central element in germinal center B cell responses, findings that have important conceptual implications for our understanding of the role of this proto-oncogene in B cell lymphomas. Recently, he also described a role for FOXO1 in establishing architectural and functional polarity in germinal centers. Comments on all these studies can be read here, here and here.
His laboratory is now actively pursuing research based on some of those studies.
David was awarded a K99/R00 “Howard Temin” Career Development Award in 2010, sponsored by the National Institutes of Health (National Cancer Institute). He was awarded a Hollis Brownstein Leukemia Research Foundation Award in 2016.