Representative Publications from Over 300 Peer-Reviewed Manuscripts

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Wang J, Hodes G, Zhang H, Zhang S, Zhao W, Golden S, Bi W, Menard C, Kana V, Leboef M, Tiano S, Esteban-Fernandez A, Xie M, Bregman D, Ho L, Dixon R, Merad M, Han MH, Russo S, Pasinetti GM. Targeting inflammation and synaptic plasticity promotes resilience against stress disorder and depression. Nature Communications; (in press, 2017).

Varghese M, Santa-Maria I, Ho L, Yemul S, Dubner L, Chudasma A, Ward L, Księżak-Reding H, Pasinetti GM. Extracellular Tau Paired Helical Filaments Differentially Affect Tau Pathogenic Mechanisms in Mitotic and Post-Mitotic Cells: Implications in Mechanisms of Tau Propagation in the BrainJ Alzheimers Dis PMID: 27567821 (2016).

Ho L, Legere M, Li T, Levine S, Hao K, Valcarcel B, Pasinetti GM. Autonomic nervous system dysfunctions as a basis for a predictive model of risk of neurological disorders in subjects with prior history of traumatic brain injury: Implications in Alzheimer’s disease. J of Alzheimer’s Dis PMID: 27911325 (2016).

Ho L, Cheng H, Wang J, Simon J, Wu Q, Zhao D, Carry E, Ferruzzi M, Faith J, Valcarcel B, Hao K, Pasinetti GM. A comprehensive database and analysis framework to incorporate multiscale data types and enable integrated analysis of bioactive polyphenols. Molecular Pharmaceutics PMID: 28665131 (2017).

Blaze J, Wang J, Ho L, Mendelev N, Haghighi F, Pasinetti GM. Polyphenolic compounds alter stress-induced patterns of global DNA methylation in brain and blood. Molecular Nutrition: (submitted, 2017.)

Docompa M, Olubu A, Wang X, Dixon R, Pasinetti GM. Glucuronidated flavonoids in neurological protection: structural analysis and approaches for chemical and biological synthesis. Journal of Agricultural and Food Chemistry: (in press, 2017).

Ho L, Ono K, Tsuji M, Mazzola P, Singh R, Pasinetti GM. Protective Roles of Intestinal Microbiota in Alzheimer’s Disease Through Mechanisms Involving Short Chain Fatty Acids. Expert Review of Neurotherapeutics: (submitted, 2017).

Singh R and Pasinetti GM. Role of gut microbes in the generation of bioactive polyphenol metabolites
in the promotion of healthy brain across the life span. Journal of Alzheimer’s Disease: (submitted, 2017).

Smith C, Frolinger T, Braithwaite J, Sims S, Pasinetti GM. Stimulation of c-fos activity by IEG-promoting phenolic metabolites. Journal of Cell Biology: (submitted, 2017).

Wang J and Pasinetti GM. Characterization of DHCA as a novel microbiome-derived epigenetic modifier in attenuation of inflammatory response in human PCMCs. Molecular Immunology: (submitted, 2017).

Frolinger T, Sharma A, De Boer S, Bell A, Sims S, Pasinetti GM. Role of polyphenols in kinase complex mammalian target of rapamycin complex 1 (mTORC1)-dependent protein translation as novel mechanisms in promoting resilence against sleep deprivation-induced cognitive impariment. PLOS ONE: (submitted, 2017)

Ward L and Pasinetti GM. Recommendations for Development of Botanical Polyphenols as “Natural Drugs” for Promotion of Resilience Against Stress-Induced Depression and Cognitive Impairment. NeuroMol Med PMID: 26402120 (2016).