News
Check this page for regular updates and news about our lab!
The Lab turns 2 years old!
Evie wins first place at Science Fair!
Alex selected for SfN’s Neuroscience Scholars Program!
Grad Student Blog!
Lab hosts 4th annual Sweis-Cai-Shuman-Fenton joint lab Super Smash Bros. tournament!
Lab presents at the Society for Neuroscience!
Lab presents at the Society for Neuroeconomics!
The lab gets mini scientist visitors!
New paper published in Science Advances!
Our collaborators recently found levels of a traditionally overlooked class of molecules, non-coding RNA, specifically LINC00473, were reduced in mPFC of women but not men diagnosed with MDD, based on post-mortem human brain tissue studies. Expressing LINC00473 in mPFC promotes resilience to stress in female mice only.
Here, we discovered LINC00473 in mPFC specifically altered change-of-mind decisions in female mice only, by enhancing sensitivity to sunk costs and how much re-evaluating recent mistakes influenced future choices. This is the first demonstration of non-coding RNA playing a role in cognition and evidence that sensitivity to sunk costs & change-of-mind regret stem from a shared value function related to negative rumination & stress susceptibility.



















































