Sen Lab Publications
Corresponding/Senior Author Publications
Hirozaku Taniguchi, Shweta S. Chavan, Andrew Chow, Joseph C. Chan, Hiroshi Mukae, Charles M. Rudin, Triparna Sen*.
Role of CD38 in anti-tumor immunity of Small Cell Lung Cancer.
2024, Frontiers in Immunology. doi: 10.3389/fimmu.2024.1248982.
Subhamoy Chakraborty, Charles Coleman, Parvathy Manoj, Deniz Demircioglu, Nisargbhai Shah, Elisa de Stanchina, Charles M. Rudin, Dan Hasson, Triparna Sen*.
De novo and histologically transformed small cell lung cancer is sensitive to lurbinectedin treatment through the modulation of EMT and NOTCH signaling pathways.
2023, Clinical Cancer Research. doi: 10.1158/1078-0432.CCR-23-0471.
Michael Offin, Jennifer L. Sauter, Sam E Tischfield, Jacklynn V. Egger, Shweta Chavan, Nisargbhai S. Shah, Parvathy Manoj, Katia Ventura, Viola Allaj, Elisa de Stanchina, William Travis, Marc Ladanyi, Andreas Rimner, Valerie W. Rusch, Prasad S. Adusumilli, John T, Marjorie G. Zauderer*, Charles M. Rudin*, Triparna Sen*.
Genomic and transcriptomic analysis of a library of patient-derived xenografts established from patients with diffuse pleural mesothelioma.
2022, Genome Medicine, vol. 14,1 127. 15 Nov. doi:10.1186/s13073-022-01129-4.
Hirokazu Taniguchi, Rebecca Caeser, Shweta S. Chavan, Yingqian A. Zhan, Andrew Chow, Parvathy Manoj, Fathema Uddin, Hidenori Kitai, Rui Qu, Omar Hayatt, Nisargbhai S. Shah, Álvaro Quintanal Villalonga, Viola Allaj, Minh N. Nguyen, Joseph Chan, Adam O. Michel, Hiroshi Mukae, Elisa de Stanchina, Charles M. Rudin*, Triparna Sen*.
WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC.
2022, Cell Reports, 39,7, 110814
Rebecca Caeser, Jacklynn Egger, Shweta Chavan, Nicholas Socci, Caitlin J. Jones, Faruk E Kombak, Marina Asher, Michael HA Roehrl, Nisargbhai S Shah, Viola Allaj, Sam E Tischfield, Amanda Kulick, Maximiliano Meneses, Christine A. Iacobuzio-Donahue, W. Victoria Lai, Umeshkumar K Bhanot, Marina K Baine, Natasha Rekhtman, Travis Hollmann, Elisa de Stanchina, John T. Poirier, Charles M Rudin*, Triparna Sen*.
Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts.
2022, Nat Commun 13, 2144
Evelyn M. Nguyen, Hirokazu Taniguchi, Joseph M Chan, Yingqian A. Zhan, Xiaoping Chen, Juan Qiu, Elisa de Stanchina, Viola Allaj, Nisargbhai S. Shah, Fathema Uddin, Parvathy Manoj, Michael Liu, Sheng F. Cai, Ross Levine, Alvaro Quintanal-Villalonga, Triparna Sen*, Andrew Chow*, Charles M. Rudin*.
Targeting LSD1 rescues MHC class I antigen presentation and overcomes PD-L1 blockade resistance in small-cell lung cancer.
2022. Journal Of Thoracic Oncology, 17(8):1014-1031. doi: 10.1016/j.jtho.2022.05.014.
Álvaro Quintanal-Villalonga, Hirozaku Taniguchi, Yingqian A. Zhan, Maysun M. Hasan, Fanli Meng, Fathema Uddin, Mark Donoghue, Helen H. Won, Shweta S. Chavan, Joseph M. Chan, Metamia Ciampricotti, Andrew Chow, Michael Offin, Jason C. Chang, Jordana Ray-Kirton, Jacklynn Egger, Umesh K. Bhanot, Joachim Silber, Christine A. Iacobuzio-Donahue, Michael H. Roehrl, Travis J. Hollmann, Helena A. Yu, Natasha Rekhtman, John T. Poirier, Brian Houck-Loomis, Richard P. Koche, Charles M. Rudin*, Triparna Sen*.
Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation.
2021, Cancer Discovery, June 21, 2021. DOI: 10.1158/2159-8290.CD-20-1863.
Álvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yingqian A Zhan, Maysun M Hasan, Shweta S Chavan, Fanli Meng, Fathema Uddin, Viola Allaj, Parvathy Manoj, Nisargbhai S Shah, Joseph M Chan, Metamia Ciampricotti, Andrew Chow, Michael Offin, Jordana Ray-Kirton, Jacklynn Egger, Umesh K Bhanot, Irina Linkov, Marina Asher, Michael Roehrl, Katia Ventura, Juan Qiu, Elisa de Stanchina, Jason C Chang, Natasha Rekhtman, Brian Houck-Loomis, Richard P Koche, Helena A Yu, Triparna Sen*, Charles M Rudin*.
Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation.
2021, Journal of Hematology & Oncology, 14, 170. doi: 10.1186/s13045-021-01186-z.
Rebecca Caeser, Christopher Hulton, Emily Costa, Vidushi Durani, Megan Little, Xiaoping Chen, Sam E Tischfield, Marina Asher, Faruk Erdem Kombak, Shweta S Chavan, Nisargbhai S Shah, Metamia Ciampricotti, Elisa de Stanchina, John T Poirier, Charles M Rudin*, Triparna Sen*.
MAPK pathway activation selectively inhibits ASCL1-driven small-cell lung cancer.
2021, iScience, 5;24(11):103224. doi: 10.1016/j.isci.2021.103224.
Corrin A. Wohlhieter, Fathema Uddin, Àlvaro Quintanal-Villalonga, John T. Poirier, Triparna Sen*, Charles M. Rudin*.
An optimized NGS sample preparation protocol for in vitro CRISPR screens.
2021, STAR Protocols (Cell Press) 2 (2), https://doi.org/10.1016/j.xpro.2021.100390.
Corrin A. Wohlhieter, Allison L. Richards, Fathema Uddin, Christopher H. Hulton, Àlvaro Quintanal Villalonga, Axel Martin, Elisa de Stanchina, Umeshkumar Bhanot, Marina Asher, Nisargbhai S. Shah, Darren J. Buonocore, Natasha Rekhtman, Ronglai Shen, Kathryn C. Arbour, Mark Donoghue, John T. Poirier, Triparna Sen*, Charles M. Rudin*.
Concurrent mutations in STK11 and KEAP1 promote ferroptosis protection and SCD1 dependence in lung cancer.
2020, Cell Reports. 1;33(9):108444. doi: 10.1016/j.celrep.2020.108444.
First-Author Publications
Triparna Sen, Bertha Leticia Rodriguez, Limo Chen, Carminia M. Della Corte Naoto Morikawa, Junya Fujimoto, Sandra Cristea, Thuyen Nguyen, Lixia Diao, Lerong Li, Youhong Fan, Yongbin Yang, Jing Wang, Bonnie S. Glisson, Ignacio Wistuba, Julien Sage, John V. Heymach, Don L. Gibbons, Lauren A. Byers.
Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer.
2019, Cancer Discovery, 9(5):646-661. doi: 10.1158/2159-8290.CD-18-1020.
- Featured in the cover of the May 2019 issue of Cancer Discovery.
- Unexpected Synergy Reveals New Therapeutic Strategy in SCLC. [Trends Pharmacol Sci. 2019]
- Delivering a STINGing Blow to Small Cell Lung Cancer via Synergistic Inhibition of DNA-Damage Response and Immune-Checkpoint Pathways. [Cancer Discov. 2019]
Triparna Sen, Carminia M. Della Corte, Snezana Milutinovic, Robert J Cardnell, Lixia Diao, Kavya Ramkumar, Carl M. Gay, C Allison Stewart, Youhong Fan, Li Shen, Ryan J. Hansen, Bryan Strouse, Michael P. Hedrick, Christian A. Hassig, John V. Heymach, Jing Wang, Lauren A Byers.
Combination treatment of the oral CHK1 inhibitor, SRA737, and low-dose gemcitabine, enhances the effect of PD-L1 blockade by modulating the immune microenvironment in small-cell lung cancer.
2019, Journal of Thoracic Oncology doi: 10.1016/j.jtho.2019.08.009.
Carmina M. Della Corte*, Triparna Sen*, Carl M. Gay*, Kavya Ramkumar, Lixia Diao, Robert J Cardnell, Bertha Leticia Rodriguez, C Allison Stewart, Vassiliki A. Papadimitrakopoulou, Laura Gibson, Jared J. Fradette, Qi Wang, Youhong Fan, David H. Peng, Marcelo V. Negrao, Ignacio I. Wistuba, Junya Fujimoto, Luisa M. Solis Soto, Carmen Behrens, Ferdinandos Skoulidis, John V. Heymach, Jing Wang, Don L. Gibbons, Lauren A. Byers. (*co-first authors)
STING pathway expression identifies non-small cell lung cancers with an immune-responsive phenotype.
2020, J Thorac Oncol. DOI: https://doi.org/10.1016/j.jtho.2020.01.009
Triparna Sen, Pan Tong, Lixia Diao, Lerong Li, You Hong Fan, Jennifer Hoff, John V Heymach, Jing Wang, Lauren Averett Byers.
Targeting AXL and mTOR pathway overcomes primary and acquired resistance to WEE1 inhibition in small cell lung cancer.
2017, Clinical Cancer Research. doi: 10.1158/1078-0432.CCR-17-1284.
Triparna Sen, Pan Tong, C. Allison Stewart, Sandra Cristea, Aly Valliani, David S. Shames, Abena B. Redwood, You Hong Fan, Lerong Li, Bonnie S. Glisson, John D. Minna, Julien Sage, Don L. Gibbons, Helen Piwnica-Worms, John V. Heymach, Jing Wang, Lauren Averett Byers.
CHK1 inhibition in small-cell lung cancer produces single-agent activity in biomarker-defined disease subsets and combination activity with cisplatin or olaparib.
2017, Cancer Research, DOI: 10.1158/0008-5472.CAN-16-3409
Manjarika De*, Sneha Ghosh*, Triparna Sen*, Md. Shadab, Indranil Banerjee, Santanu Basu, Nahid Ali. (*co-first authors)
A Novel Therapeutic Strategy for Cancer Using Phosphatidylserine Targeting Stearylamine-Bearing Cationic Liposomes.
2017, Molecular Therapy-Nucleic Acids. DOI: http://dx.doi.org/10.1016/j.omtn.2017.10.019.
Triparna Sen, Kirat K. Ganguly, Amitava Chatterjee.
Focal adhesion kinase induces matrix metalloproteinase-2 by involving α5β1-mediated signaling in breast cancer cell, MCF-7.
2015, Acta Medica International, 2 (1), 29-39.
Triparna Sen and Amitava Chatterjee.
Epigallocatechin-3-gallate (EGCG) downregulates EGF-induced MMP- 9 in breast cancer cells: involvement of integrin receptor α5β1 in the process.
2011, European Journal of Nutrition, 50 (6), 465-478
Triparna Sen, Anindita Dutta, Gargi Maity, Amitava Chatterjee.
Fibronectin induces matrix metalloproteinase-9 (MMP-9) in human laryngeal carcinoma cells by involving multiple signaling pathways.
2010, Biochimie, 92(10): 1422-34.
Triparna Sen, Anindita Dutta, Amitava Chatterjee.
Epigallocatechin-3-gallate (EGCG) downregulates gelatinase-B (MMP-9) by involvement of FAK/ERK/NFkB and AP-1 in the human breast cancer cell line MDA-MB-231.
2010, Anticancer Drugs, 21(6):632-44.
Triparna Sen, Shuvojit Moulik, Anindita Dutta, Paromita Roy Choudhury, Aniruddha Banerji, Shamik Das, Madhumita Roy, Amitava Chatterjee.
Multifunctional effect of epigallocatechin-3-gallate (EGCG) in downregulation of gelatinase-A (MMP-2) in human breast cancer cell line MCF-7.
2009, Life Sciences, 13; 84(7-8):194-204.
Co-Author Publications
Virginia Corbett, Triparna Sen, Aman Chauhan.
Role of CDK4/6 inhibitors in targeting Rb proficient small cell lung cancer
2024, Translational Lung Cancer Research doi: 10.21037/tlcr-23-337.
Charles M Rudin, David Balli, W Victoria Lai, Allison L Richards, Evelyn Nguyen, Jacklynn V Egger, Noura J Choudhury, Triparna Sen, Andrew Chow, John T Poirier, William J Geese, Matthew D Hellmann, Ann Forslund.
Clinical Benefit From Immunotherapy in Patients With SCLC Is Associated With Tumor Capacity for Antigen Presentation
2023, J Thorac Oncol. doi: 10.1016/j.jtho.2023.05.008.
Andrew Chow,….Triparna Sen, Elisa de Stanchina, Jedd D Wolchok, Taha Merghoub, Charles M Rudin.
The ectonucleotidase CD39 identifies tumor reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer.
2023, Immunity, 2023 Jan 10; 56(1):93-106.e6. doi: 10.1016/j.immuni.2022.12.001.
Hsiao-Yun Chen, Yavuz T. Durmaz, Yixiang Li, Amin H. Sabet, Amir Vajdi, Thomas Denize, Emily Walton, Yasmin Nabil Yaimon, John G. Doench, Navin R. Mahadevan, Julie-Aurore Losman, David A. Barbie, Michael Y. Tolstorukov, Charles M. Rudin, Triparna Sen, Sabina Signoretti, and Matthew G. Oser.
Regulation of Neuroendocrine Plasticity by the RNA-Binding Protein ZFP36L1.
2022, Nat Commun, 13(1):4998.
Alvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yuan Hao, Andrew Chow, Yingqian A. Zhan, Shweta S. Chavan, Fathema Uddin, Viola Allaj, Parvathy Manoj, Nisargbhai S. Shah, Joseph M. Chan, Michael Offin, Metamia Ciampricotti, Jordana Ray-Kirton, Jacklynn Egger, Umesh Bhanot, Irina Linkov, Marina Asher, Michael H. Roehrl, Juan Qiu, Elisa de Stanchina, Travis J.Hollmann, Richard P. Koche, Triparna Sen, John T. Poirier, Charles M. Rudin.
XPO1 inhibition sensitizes small-cell lung cancer to first- and second-line chemotherapy.
2021 Cancer Research, 82(3):472-483.
Joseph M Chan, Álvaro Quintanal-Villalonga, Vianne Ran Gao, Yubin Xie, Viola Allaj, Ojasvi Chaudhary, Ignas Masilionis, Jacklynn Egger, Andrew Chow, Thomas Walle, Marissa Mattar, Dig VK Yarlagadda, James L. Wang, Fathema Uddin, Michael Offin, Metamia Ciampricotti, Besnik Qeriqi, Amber Bahr, Elisa De Stanchina, Umesh K Bhanot, W Victoria Lai, Matthew J Bott, David R Jones, Arvin Ruiz, Marina K. Baine, Yanyun Li, Natasha Rekhtman, John T Poirier, Tal Nawy, Triparna Sen, Linas Mazutis, Travis Hollmann, Dana Pe’er, Charles M Rudin.
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer.
2021 Cancer Cell, S1535-6108(21)00497-9. doi: 10.1016/j.ccell.2021.09.008.
Metamia Ciampricotti, Triantafyllia Karakousi, Allison L. Richards, Àlvaro Quintanal-Villalonga, Angeliki Karatza, Rebecca Caeser, Emily A Costa, Viola Allaj, Parvathy Manoj, Kyle B. Spainhower, Francisco J Sanchez-Rivera, Janneke Jaspers, Anastasia-Maria Zavitsanou, Danilo Maddalo, Andrea Ventura, William M. Rideout III, Elliot H. Akama-Garren, Tyler Jacks, Mark Donoghue, Triparna Sen, Trudy G Oliver, John T Poirier, Thales Papagiannakopoulos*, Charles M Rudin*.
Rlf-Mycl gene fusion drives tumorigenesis and metastasis in a mouse model of small cell lung cancer.
2021 Cancer Discovery, 11(12):3214-3229. DOI: 10.1158/2159-8290.CD-21-0441.
Kathryn Tully, Salomon Tendler, Lukas Carter, Sai Kiran Sharma, Zachary Samuels, Komal Mandleywala, Joshua Korsen, Avelyn Mae Delos Reyes, Alessandra Piersigilli, William Travis, Triparna Sen, Naga Vara Kishore Pillarsetty, John Poirier, Charles Rudin, and Jason Lewis.
Radioimmunotherapy Targeting Delta-like Ligand 3 in Small Cell Lung Cancer.
2021, Clinical Cancer Research, 28(7):1391-1401. doi: 10.1158/1078-0432.CCR-21-1533
Andrew Chow, Sara Schad, Michael D. Green, Matthew D. Hellmann, Viola Allaj, Nicholas Ceglia, Nisarg Shah, Sai Kiran Sharma, Marissa Mattar, Joseph Chan, Hira Rizvi, Hong Zhong, Cailian Liu, Hongyu Shi, Yonina Bykov, Dmitriy Zamarin, Sadna Budhu, Corrin Wohlhieter, Giulia Zago, Fathema Uddin, Aditi Gupta, Inna Khodos, Jessica J. Waninger, Angel Qin, Andrew McPherson, Sohrab P. Shah, Vinod Balachandran, Weiping Zou, Katherine Panageas, Jason S. Lewis, Justin Perry Elisa de Stanchina, Triparna Sen, John Thomas Poirier, Jedd D. Wolchok, Charles M. Rudin, Taha Merghoub.
Tim-4+ Cavity-Resident Macrophages Impair Anti-Tumor CD8+ T cell Immunity.
2020, Cancer Cell, S1535-6108(21)00272-5. DOI: https://doi.org/10.1016/j.ccell.2021.05.006.
Marina K Baine, Min-Shu Hsieh, W. Victoria Lai, Jacklynn V. Egger, Achim Jungbluth, Yahya Daneshbod, Amanda Beras, Rowanne Spencer, Jessica Lopardo, Francis Bodd, Joseph Montecalvo, Jennifer L. Sauter, Jason C. Chang, Darren J. Buonocore, William D. Travis, Triparna Sen, John T. Poirier, Charles M. Rudin, Natasha Rekhtman.
Small Cell Lung Carcinoma Subtypes Defined by ASCL1, NEUROD1, POU2F3 and YAP1: Comprehensive Immunohistochemical and Histopathologic Characterization.
2020, Journal of Thoracic Oncology. DOI:https://doi.org/10.1016/j.jtho. 2020.09.009.
Sandra Cristea, Garry L. Coles, Daniel Hornburg, Julia Arand, Siqi Cao, Triparna Sen, Stuart Williamson, Laurent Le Cam, Lauren Byers, Michael P. Snyder, Kévin Contrepois, Julien Sage.
The MEK5-ERK5 kinase axis controls lipid metabolism in small-cell lung cancer.
2020, Cancer Research. DOI: 10.1158/0008-5472.CAN-19-1027.
Marcel A. Dammert, Johannes Brägelmann, Rachelle R. Olsen, Stefanie Böhm, Niloufar Monhasery, Christopher P. Whitney, Milind D. Chalishazar, Hannah L. Tumbrink, Matthew R. Guthrie, Sebastian Klein, Abbie S. Ireland, Jeremy Ryan, Anna Schmitt, Annika Marx, Luka Ozretic, Roberta Castiglione, Carina Lorenz, Ron Jachimowicz, Elmar Wolf, Martin Peifer, Roman K. Thomas, John T. Poirier, Reinhard Büttner, Triparna Sen, Lauren A. Byers, H. Christian Reinhardt, Anthony Letai, Trudy G. Oliver, Martin L. Sos.
MYC paralogs orchestrate apoptotic priming and differential BCL2/MCL1 dependency in small cell lung cancer.
2019, Nat Commun. 2019 Aug 2;10(1):3485. doi: 10.1038/s41467-019-11371-x.
Carl M. Gay, Pan Tong, Robert J. Cardnell, Triparna Sen, Rasha O. Bara, Jun Ma, Xiao Su, Nene N. Kalu, Upasana Banerjee, Faye Johnson, Chris Wakefield, John V. Heymach, Jing Wang, Lauren A. Byers.
Differential Sensitivity Analysis for Resistant Malignancies (DISARM), an integrated drug screening analysis, identifies common candidate drugs across platinum-resistant cancers.
2018, Clinical Cancer Research, doi: 10.1158/1078-0432.CCR-18-1129.
Robert Cardnell, Lerong Li, Triparna Sen, Rasha Bara, Pan Tong, Junya Fujimoto, Abbie Ireland, Matthew Guthrie, Sheila Bheddah, Upasana Banerjee, Nene Kalu, You Fan, Scott Dylla, Faye Johnson, Ignatio Wistuba, Trudy Oliver, John Victor Heymach, Bonnie Glisson, Jing Wang, Lauren A. Byers.
Protein expression of TTF1 and cMYC define distinct molecular subgroups of small-cell lung cancer with unique vulnerabilities to aurora kinase inhibition, DLL3 targeting and other targeted therapies.
2017, Oncotarget, 8(43): 73419–73432
C. Allison Stewart, Pan Tong, Robert Cardnell, Triparna Sen, Lerong Li, Carl Gay, Fatemah Masrorpour, You Fan, Rasha Bara, Ying Feng, Yuanbin Ru, Junya Fujimoto, Samrat Kundu, Leonard Post, Karen Yu, Yuqiao Shen, Bonnie Glisson, Ignatio Wistuba, John Victor Heymach, Don L. Gibbons, Jing Wang, and Lauren Byers.
Dynamic Variations in Epithelial-to-Mesenchymal Transition (EMT), ATM, and SLFN11 Govern Response to PARP Inhibitors and Cisplatin in Small Cell Lung Cancer.
2017, Oncotarget, 25;8 (17):28575-28587. doi: 10.18632/oncotarget.15338
Subhra Prakash Hui, Dhriti Sengupta, Serene Gek Ping Lee, Triparna Sen, Sudip Kundu, Sinnakaruppan Mathavan, Sukla Ghosh.
Genome-wide expression profiling during spinal cord regeneration identifies comprehensive cellular responses in zebrafish.
2014, PLoS ONE, 9(1):e84212
Kirat K. Ganguly, Triparna Sen, Jaydip Biswas, Amitava Chatterjee.
Studies on focal adhesion kinase in human breast cancer cell MDA-MB-231.
2012, Advances in biological chemistry, 2, 29-42
Kirat Kumar Ganguly, Triparna Sen, Syamsundar Mandal, Jaydip Biswas, Amitava Chatterjee.
Studies on Focal Adhesion Kinase in Human Breast Cancer Tissue.
2012, Journal of Cancer Therapy, 3, 7-19
Hrishikesh Sil, Triparna Sen, Amitava Chatterjee.
Fibronectin-Integrin (α5β1) Modulates Migration and Invasion of Murine Melanoma Cell Line B16F10 by Involving MMP-9.
2011, Oncology research, 19, 335- 348(14)
Gargi Maity, Triparna Sen, Amitava Chatterjee.
Laminin induces matrix metalloproteinase-9 expression and activation in human cervical cancer cell line (SiHa).
2011, Journal of Cancer Research and Clinical Oncology, 137, 347-357
Gargi Maity, Paromita Roy Choudhury, Triparna Sen, Kirat Kumar Ganguly, Hrishikesh Sil, Amitava Chatterjee.
Culture of human breast cancer cells line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity.
2011, Tumor biology, 32, 129-138.
Anindita Dutta, Triparna Sen, Amitava Chatterjee.
All-trans retinoic acid (ATRA) downregulates MMP-9 by modulating its regulatory molecules.
2010, Cell Adhesion and Migration, 4(3), 409-418
Anindita Dutta, Triparna Sen, Amitava Chatterjee.
Culture of K562 human myeloid leukemia cells in presence of fibronectin expresses and secretes MMP-9 in serum-free culture medium.
2010, International Journal of Clinical and Experimental Pathology, 3(3):288-302
Gargi Maity, Shabana Farheen, Aniruddha Banerji, Paromita Roy Choudhury, Triparna Sen, Anindita Dutta, Amitava Chatterjee.
Fibronectin-integrin mediated signaling in human cervical cancer cells (SiHa).
2010, Molecular and Cellular Biochemistry, 336(1-2):65-74
Anindita Dutta, Triparna Sen, Aniruddha Banerji, Shamik Das, Amitava Chatterjee.
Studies on Multifunctional Effect of All-Trans Retinoic Acid (ATRA) on Matrix Metalloproteinase-2 (MMP-2) and Its Regulatory Molecules in Human Breast Cancer Cells (MCF-7).
2009, Journal of Oncology, 2009:627840
Shuvojit Moulik, Triparna Sen, Anindita Dutta, Aniruddha Banerji, Chinmoy Ghosh, Shamik Das, and Amitava Chatterjee.
Phosphatidylinositol 3-Kinase and NF-kB Involved in Epidermal Growth Factor-Induced Matrix Metalloproteinase-9 Expression.
2008, Journal of Cancer Molecules, 4(2): 55-60
Reviews and Editorials
Utsav Sen, Charles Coleman, Triparna Sen*.
Stearoyl coenzyme A desaturase-1: multitasker in cancer, metabolism, and ferroptosis.
2023, Trends Cancer. Apr 5, doi: 10.1016/j.trecan.2023.03.003
Triparna Sen.
Identifying and targeting the Achilles heel of a recalcitrant cancer.
Science Translational Medicine. 2021, 13 (605), DOI: 10.1126/scitranslmed.abj6946.
Featured on the cover of the August 2021 issue.
Álvaro Quintanal-Villalonga, Joseph M. Chan, Helena A. Yu, Dana Pe’er, Charles L. Sawyers, Sen Triparna* & Charles M. Rudin* (*corresponding author).
Lineage plasticity in cancer: a shared pathway of therapeutic resistance.
2020, Nature Reviews Clinical Oncology. 17, 360–371 DOI: https://doi.org/ 10.1038/s41571-020-0340-z
Hirokazu Taniguchi, Triparna Sen*, Charles M. Rudin* (*corresponding author).
Targeted therapies and biomarkers in small cell lung cancer.
2020, Front.Oncol.-Thoracic Oncology. 10: 741. doi: 10.3389/fonc.2020.00741
Triparna Sen, Carl M. Gay, Lauren A. Byers.
Targeting DNA damage repair in small cell lung cancer- and the biomarker landscape.
Translational Lung Cancer Research, 2018; 7(1):50-68. doi: 10.21037/tlcr.2018.02.03.
Fathema Uddin, Charles M Rudin, Triparna Sen* (*corresponding author).
CRISPR Gene Therapy: Applications, Limitations, and Implications for the Future.
2020 Front. Oncol.-Cancer Genetics 7;10:1387. doi: 10.3389/fonc.2020.01387
Rebecca Caeser, Triparna Sen* (*corresponding author).
Should WEE(1) CHK(1) in on the FAM(122A)ily? 2020 Molecular Cell. 80 (3); 377-378.
Contact Us
Principal Investigator
Triparna Sen, PhD
Associate Professor
Co-Director, Lung Cancer PDX Program
E-mail
triparna.sen@mssm.edu
Lab Address
Icahn School of Medicine at Mount Sinai
1425 Madison Avenue, 15th Floor
New York, NY 10029
United States
Office Address
1425 Madison Avenue, 15th Floor
New York, NY 10029
United States