EPPIC-Net

The Icahn School of Medicine at Mount Sinai (ISMMS) EPPIC-Net Specialized Clinical Center
NIH U24 NS113849

EPPIC-Net (Early Phase Pain Investigation Clinical Network) is a consortium of centers with the shared goal of accelerating development of non-addictive treatments for pain. As a site in this consortium, Mount Sinai offers patients participation in these clinical trials. Currently we have an open clinical trial for people with painful diabetic peripheral neuropathy (PDPN), learn more here. If you are interested in participating, we’d love to speak to you! Call us at 212-241-0190, or email us at paired.project@mssm.edu.

EVA

Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV

NIH R01DK122853

The autonomic nervous system, including the vagus nerve, is an important controller of immune function, and our prior research has shown that vagal dysfunction is linked to small intestinal bacterial overgrowth (SIBO) and signs of inflammation in the blood of people living with HIV. 

The EVA project explores pathways linking autonomic dysfunction to inflammation in people living with HIV compared to people without HIV, focusing on the gastrointestinal tract. We are also testing the effects of a drug, pyridostigmine, which can increase levels of the vagus nerves’ neurotransmitter, acetylcholine, and non-invasive vagal nerve stimulation.

SALUD

Study of Aging Latinas/os for Understanding Dementia in HIV

NIH R01AG065110   

This project investigates brain health disparities in older Black and Latino adults. Learn more here.

Global HIV Pain Task Force

The Global HIV Pain Task Force is a group of researchers and people with lived experience from the United States, United Kingdom, Canada and South Africa. We study, treat and live with chronic pain and HIV, and are passionately committed to finding the safe and effective treatments we desperately need. Read about our research agenda here!

 

TOWER

Toward safer opioid prescribing for chronic pain in high risk populations: implementing the Centers for Disease Control Guideline (CDC) guideline in the primary care HIV clinic.

AHRQ R18 HS025641   

The TOWER study is complete! Its purpose was to determine the best way of supporting HIV primary care providers in adopting safer opioid prescribing practices. Read the results:

PAIRED Project
paired.project@mssm.edu
212-241-0190