Saurabh Mehandru, MD, straddles the world of clinical care and laboratory based investigation. He graduated from the University College of Medical Sciences, Delhi University, India and then completed residency training in Internal Medicine at the NYU School of Medicine where he also served as Medical Chief Resident. He received subspecialty training in Clinical Gastroenterology at The Icahn School of Medicine at Mount Sinai.
Dr Mehandru undertook post-doctoral training at the Rockefeller University, first working in the Laboratory of Dr. David Ho (with Dr. Martin Markowitz) and then in the Laboratory of Dr. Ralph Steinman, Nobel Laureate in Physiology or Medicine (2011).
After finishing his post-doctoral training, Dr. Mehandru was invited to join the faculty at Mount Sinai where in addition to serving as an Associate Professor of Gastroenterology, he leads a laboratory of Mucosal Immunology since 2013. Dr. Mehandru’s research interests include mucosal trafficking, the host-pathogen interface, dendritic cell biology and mucosal immunopathology in primary and acquired immunodeficiency states. He is an NIH-funded investigator who has received multiple awards.
Mathieu Uzzan, MD, is a PhD student focusing on gut trafficking at steady state and during mucosal inflammation. He is being co-mentored by Dr. Mehandru at the Icahn School of Medicine at Mount Sinai and Dr. Bouhnik at Université Denis Diderot, Paris 7 in France. Dr. Uzzan completed his medical school training from Université Pierre et Marie Curie, Paris 6 in France. He then completed residency training in Gastroenterology at Assistance Publique des Hôpitaux de Paris, APHP, France. He was awarded a Master of Science degree by the Université Denis Diderot, Paris 7, during which he developed a micro-RNA-based biomarker to predict response to treatment in patients with severe ulcerative colitis. Dr. Uzzan’s research focuses on the pathogenesis of Inflammatory Bowel Disease.
Akihiro Seki, PhD, is a Post-Doctoral Fellow studying the role of the microbiome in affecting dendritic cell function. Dr. Seki graduated the medical school of Toyama Medicine and Pharmaceutical University in Japan. He started his clinical practice as gastroenterologist, and at the same time he started his basic science career at the Graduate School of Medical Science, Kanazawa University, Japan. He was awarded his PhD in Medical Science at the Kanazawa University.
Louise Leyre, Msc, is an associate researcher focusing on the HIV persistence in the gut. She obtained a Bachelor of Science in Biology from the University of Lausanne in Switzerland. In 2018, she was awarded a Master of Science by the University of Montréal, Canada, during which she worked on the establishment and the persistence of the HIV reservoir in acute infection under the supervision of Dr. Nicolas Chomont.
Francesca Cossarini, MD is a research fellow in the Division of Infectious Disease at Icahn School of Medicine at Mount Sinai. She graduated from medical school at the Universita’ degli Studi di Trieste, Italy and worked as a clinical research investigator at the Universita’ Vita-Salute San Raffaele in Milan, Italy where she focused on antiretroviral treatment and clinical outcomes of HIV-infected patients. She spent a research year working on HIV reservoir in the Frank Maldarelli Lab at the NIH and then completed her medicine residency at Albert Einstein College of Medicine – Jacobi Hospital in New York where she worked on a project to improve HIV screening strategies in patients accessing medical care. She is now completing her Infectious Disease Fellowship and is working on the interplay of the GUT microbiome and mucosal immunity in HIV infected patients.
Harpriya Singh, MBBS, is a research student studying the role of mucosal immune system in Inflammatory Bowel Diseases. Harpriya completed her medical school training in Government Medical College, Amritsar in India. She then worked as Research Intern at Stanford University in Habtezion Lab, where she studied the role of dendritic cells in regards to IBD in a colitis mouse model.
Keshav Sharma, BS is a master’s student studying the role of mucosal immune system in Inflammatory Bowel Disease. He obtained his Bachelor’s degree from from Imperial College, London (2015-18) where he focused on the immune system and infectious diseases. He plans to apply for a PhD in Immunology in the future.
Gustavo Martinez-Delgado, PhD is a Research Manager of the Division of Gastroenterology at Icahn School of Medicine at Mount Sinai. He graduated from the Universidad Nacional Autonoma de Mexico, UNAM. He is a biologist with postgraduate studies in neuroscience (MSc), and biomedical science (Ph.D.), followed by training in the field of molecular virology in the Garcia-Sastre Laboratory in the Department of Microbiology at Icahn School of Medicine at Mount Sinai.
Alexandra Livanos, MD PhD, is a Gastroenterology Fellow at the Icahn School of Medicine at Mount Sinai Hospital. She completed her MD/PhD at New York University. Her PhD focused on the role of early-life gut microbiome perturbation on the development of type 1 diabetes in NOD mice under the mentorship of Dr. Martin Blaser. Subsequently, she completed her residency training at NYP-Columbia in Internal Medicine and then started her GI Fellowship at the Icahn School of Medicine at Mount Sinai Hospital in 2018. She is now finishing her fellowship and plans to continue research focusing on the interactions between the intestinal immune system and the gut microbiota in inflammatory bowel disease as well as investigating potential biomarkers.
Divya Jha, PhD, is a Postdoctoral Fellow in the Division of Gastroenterology at Icahn School of Medicine at Mount Sinai. Dr. Jha obtained her Bachelor of Science in Life Sciences from Miranda House, and Master of Science in Biomedical Science from Dr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, India. She was awarded her PhD at the National Institute of Immunology, New Delhi, where she worked on spray-dried alum and polymeric nanoparticle-based vaccine formulations to tailor the immune responses in mouse models. She joined as a Postdoctoral Fellow in Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai, New York, to study the post-transcriptional modifications of long non-coding RNAs that regulate the cardiac functions and the role of exosomes in cardiac regeneration. Currently, she works on deciphering the role of intestinal intraepithelial lymphocytes in the pathogenesis of Inflammatory Bowel Disease (IBD), Graft Versus Host Disease (GVHD), Common Variable Immune Deficiency (CVID) and Human Immunodeficiency Virus (HIV) infection. She also focuses on elucidating the changes in intestinal myeloid cell populations in IBD patients
Minami Tokuyama, BS, is a medical student at the Icahn School of Medicine at Mount Sinai, currently taking a scholarly year. She is studying tissue resident memory T cells in the intestines including their regional distributions in health and their aberrations in active and treated IBD. She also is investigating COVID-19 infection in the GI tract.