Publications

Kho C, Lee A., Jeong D, Oh JG, Channine AH, Kizana E, Park WJ, & Hajjar RJ. SUMO1-dependent modulation of SERCA2a in heart failure. Nature (2011) 477: 601-605. PMID: 21900893.

Tilemann L, Lee A, Ishikawa K, Aguero J, Rapti K, Santos-Gallego C, Kohlbrenner E, Fish K, Kho C, & Hajjar RJ. SUMO-1 gene transfer improves cardiac function in a large animal model of heart failure. Science Translational Medicine (2013) 5:211ra159. PMID: 24225946.

Lee A, Jeong D, Mitsuyama S, Oh JG, Liang L, Yoshiyuki I, Sadoshima J, Hajjar RJ* & Kho C* The role of SUMO-1 in cardiac oxidative stress and hypertrophy. Antioxidant & Redox Signaling (2014) 21:1986-2001. PMID: 24893265. 

Kho C, Lee, A, Jeong, D, Oh, JG, Gorski, PA, Fish, K, Sanchez, R, DeVita, R, Christensen, G, Dahl, R, Hajjar RJ. Small Molecule Activation of SERCA2a SUMOylation as a Novel Therapeutic Strategy for the Treatment of Heart Failure. Nature Communications (2015) 6:7967. PMID: 26068603.