Ji Lab

Principal Investigator

Andrew Ji, MD

Andrew Ji, MD

Faculty Profile

Assistant Professor, Department of Dermatology
Assistant Professor, Department of Oncological Sciences (secondary)
Assistant Professor, Cell, Developmental & Regenerative Biology (secondary)

Dr. Andrew Ji is an Assistant Professor of Dermatology, Oncological Sciences, and Cell, Developmental & Regenerative Biology at the Icahn School of Medicine at Mount Sinai. Prior to joining Mount Sinai, he was a Clinical Instructor at Stanford University and postdoctoral fellow in the Lab of Dr. Paul Khavari. He received his S.B. in biological engineering from MIT, his M.D. from Weill Cornell Medical College, and completed dermatology residency training at Stanford. During medical school, he completed an HHMI Fellowship in the Lab of Dr. Joan Massagué at Memorial Sloan Kettering. His lab focuses on understanding how intercellular communication in the skin microenvironment contributes to both pathogenesis and treatment resistance of diseases such as cancer and inflammatory skin diseases by leveraging single-cell and multi-omic approaches. He has earned numerous awards for his work, including a Damon Runyon Physician-Scientist Training Award, NIH/NCI K08 Award, 2021 American Skin Association Milstein Research Scholar Award, and 2023 American Academy of Dermatology Young Investigator Award. Dr. Ji’s lab is part of the Black Family Stem Cell Institute and Tisch Cancer Institute. In addition to research, he maintains a weekly clinic where he sees general dermatology patients.

 

Postdoctoral Fellows

Ichiro Imanishi, DVM, PhD

Ichiro Imanishi, DVM, PhD

Postdoctoral Fellow

Ichiro is a postdoctoral fellow in our laboratory. Prior to joining Mount Sinai, he was an Assistant Professor at Kitasato University School of Medicine in Japan, where he worked to elucidate the pathogenetic mechanisms of staphylococcal skin infections. He received a PhD in Veterinary Medicine from Gifu University, Japan, and he previously worked in clinical practice as a board-certified veterinarian in dermatology in Japan. He is now focused in our laboratory on the hypothesis that fibroblast subpopulations located in the skin might regulate inflammatory diseases of the skin, utilizing spatial transcriptome analysis and multi-omics approaches to understand fibroblast subpopulations and cell-to-cell communication with inflammatory cells. He enjoys cooking, tennis, and learning English on the weekends, but these days his biggest stress reliever is enjoying events with his colleagues

 

 

 

 

 

 

 

Harkirat Singh Sandhu, PhD

Harkirat Singh Sandhu, PhD

Postdoctoral Fellow

Harkirat is a postdoctoral fellow working on delineating the mechanisms of cancer cell plasticity. She obtained her PhD in Human Genetics and Stem Cell Biology from Guru Nanak Dev University, India. Later she did her postdoctoral training in prostate cancer plasticity and therapeutic resistance at Icahn School of Medicine at Mount Sinai. Harkirat is passionate about exploring the intricacies underlying tumor heterogeneity and disease resistance through the lens of lineage plasticity. Outside of work, she loves to draw, read non-fiction books and enjoy the company of nature.

 

 

 

 

Graduate Students

Paula Restrepo

Paula Restrepo

PhD Student, GGS

Paula Restrepo is a PhD student whose research focuses using computational multi-omics to understand intratumoral heterogeneity, tumor evolution, and the tumor-immune microenvironment in cancer. She received her BA in biology from George Washington University in 2017 prior and began the PhD program in Biomedical Sciences at The Icahn School of Medicine at Mount Sinai in 2022. Prior to joining the Ji Lab, she held bioinformatics roles at Mount Sinai in the Genetics and Genomics Department characterizing intratumoral heterogeneity in liver and brain cancer, as well as in the Tisch Cancer Institute identifying predictive biomarkers and implementing genomics-based clinical decision making algorithms in multiple myeloma. Outside the lab, she enjoys watercolor painting, traveling, and spending time with her two cats.

 

 

 

 

 

 

 

Raman Gill

Raman Gill

PhD Student, DRS

Raman Gill is a PhD student focusing on stromal contributions to skin inflammation and disease. She received her BS from the University of Wisconsin-Madison in Material Science & Engineering and Biochemistry and a master’s in Translational Medicine from UC Berkeley/UCSF. Prior to joining the Ji lab, she worked as a Research Associate II at Caribou Biosciences developing iPSC derived NK cells for solid tumors. In her free time Raman enjoys traveling, cooking, and playing board games. She started the PhD program in Biomedical Sciences at The Icahn School of Medicine at Mount Sinai in the Development, Regeneration, and Stem Cells (DRS) MTA in 2022.

 

 

 

 

 

 

 

Arjun Nair

Arjun Nair

MS in Biomedical Sciences Student

Arjun graduated with Research Scholar Honors from the University of Pennsylvania’s Roy and Diana Vagelos Program in Life Sciences and Management. He holds a bachelor of arts in biology from the College of Arts and Sciences and a bachelor of science in economics from Wharton, concentrating in healthcare management and finance. His research interests lie in identifying therapeutics targeting the tumor microenvironment and next-generation sequencing technologies. Prior to joining the Ji Lab, Arjun was a research assistant in the synthetic immunology division at Intrexon and an associate at Locust Walk, a boutique biopharma consulting and investment banking firm. Outside of the lab, Arjun enjoys basketball, soccer, and learning to produce music.

 

 

 

 

 

Staff

Alexis Wilder

Alexis Wilder

Associate Researcher

Alexis completed her undergraduate education at The George Washington University in 2023, majoring in Biology and Mathematics and minoring in Chemistry. As a prospective medical student, she is interested in the discovery of intracellular communication networks that are associated with various diseases. She enjoys the perspective that single-cell and spatial transcriptomics data provides in understanding these cell-cell interactions. In her free time, Alexis enjoys running, attending sports games, and taking long walks around the city.

Medical Students

Grace Hren

Grace Hren

Medical Student Research Fellow

Grace is a medical student at Stony Brook Renaissance School of Medicine currently pursuing a research year between her third and fourth year of medical school in the Ji Lab. She received her BS in Biology and BS in Psychology from the University at Albany in 2019. Her passion for scientific research, as well as her strong interest in Dermatology, led her to join the Ji Lab. She is looking forward to utilizing spatial multi-omic techniques to further the lab’s current research in squamous cell carcinomas in high-risk populations. In her free time she enjoys going to the beach, hanging out with her cat, and cooking.

 

Jenny Chung

Jenny Chung

Summer Volunteer

Jenny Chung is an incoming first year medical student in the Sophie Davis BS/MD program at CUNY School of Medicine, which aims to foster physicians that will meet the healthcare needs of underserved communities. She began working in the lab the summer of 2023 and primarily focuses on exploring fibroblast subpopulations in the skin that may regulate inflammatory skin conditions. In her free time, Jenny enjoys traveling, crocheting, and nail art.

 

Alumni

  • Aubrey Houser, Associate Researcher
  • Larry Chen, Associate Researcher
  • Abiha Kazmi, Undergraduate Researcher
  • Gayatri Mainkar, Rotation PhD Student
  • Hongyu Wang, Visiting PhD Student
  • Brian Soong, Rotation MD/PhD Student
  • Thinh Nguyen, Rotation PhD Student
  • Arianna Piñeiro, Associate Researcher