Publications

2026

 

Liu D, Duca ED, Delaleu N, Lau M, Pulsinelli J, de Rosa JC, Bar J, Estrada Y, Gudjonsson J, Julia V, Guttman-Yassky E.  

Tape Strip Transcriptomics Reveal Nemolizumab Effects on Pruritus, Hyperplasia, Inflammation, and Extracellular Matrix Markers in Patients With Moderate-to-Severe Atopic Dermatitis 

Allergy. 2026 Sep 4 

DOI: 10.1111/all.70505 

 

Kim M, Del Duca E, Correa Da Rosa J, Pulsinelli J, Estrada Y, Xu D, Chan G, Chen A, Güler E, Page K, Guttman-Yassky E.  

Effect of Abrocitinib on the Skin Microbiome in Patients With Moderate-to-Severe Atopic Dermatitis  

Allergy. 2026 Aug 2 

DOI: 10.1111/all.70467 

Avallone G, Beaziz J, Manzo Margiotta F, Langer K, Del Duca E, Guttman-Yassky E.  

Atopic Dermatitis: New Targets and Emerging Systemic Therapies  

Am J Clin Dermatol. 2026 Jun 27. 

DOI: 10.1007/s40257-026-01054-x 

Dahabreh D, Patel D, Del Duca E, Corriden R, Brockstedt DG, Guttman-Yassky E.  

The biological role of CCR4 and its ligands CCL17 and CCL22 in atopic dermatitis: therapeutic implications and future directions  

Expert Opin Ther Targets. 2026 Jun 

DOI: 10.1080/14728222.2026.2690137 

Sacknovitz Y, Ma R, Zhou MH, Kent J, Ng B, Erem AS, Litman T, Tolu SS, Pro B, Estrada YD, Guttman-Yassky E, Gru AA, Brunner PM, Geskin LJ. 

Serum proteomic and single-cell transcriptomic profiling reveals immunoproteomic features distinguishing early-stage mycosis fungoides from atopic dermatitis  

J Invest Dermatol. 2026 Jun 

DOI: 10.1016/j.jid.2026.05.026 

Zhou J, Fiedler J, Guttman-Yassky E.  

Beyond T helper 2 cells: Integrating immune, barrier, microbial, and neuroimmune pathways in atopic dermatitis pathogenesis  

J Am Acad Dermatol. 2026 May  

DOI: 10.1016/j.jaad.2026.01.076 

Beaziz J, Avallone G, Langer K, Del Duca E, Navrazhina K, He H, Guttman-Yassky E.  

Skin aging: Mechanistic insights and targeted therapeutic strategies  

J Allergy Clin Immunol. 2026 May 27 

DOI: 10.1016/j.jaci.2026.05.015 

Liu D, Del Duca E, Brunner P, Avallone G, Beaziz J, Metukuru R, Lin X, Estrada Y, Lau M, Largen J, Ungar B, Guttman-Yassky E  

Comprehensive molecular profiling of Hispanic, Black, Asian, and White patients with atopic dermatitis via tape strip RNA sequencing and serum proteomics

J Allergy Clin Immunol. 2026 Jul  

DOI: 10.1016/j.jaci.2026.04.010 

Zhou J, Margiotta FM, Duca ED, Fiedler J, Cices A, Ungar B, Guttman-Yassky E.  

Comorbidities of atopic dermatitis: Emerging evidence and clinical considerations  

Ann Allergy Asthma Immunol. 2026 Jul 

DOI: 10.1016/j.anai.2026.04.015 

Kim M, Manson M, Liu Y, Rangel S, Kaplan N, Rabbaa L, Choate K, Bose S, Metukuru R, Lin X, Largen J, Shah M, Estrada YD, Paller AS, Guttman-Yassky E.  

Tape strips capture immune and epidermal hyperplasia markers in the major orphan ichthyoses  

J Invest Dermatol. 2026 Apr 

DOI: 10.1016/j.jid.2026.03.033 

Yamamura K, Garcet S, Gonzalez J, Zhou J, Fiedler J, Miura S, Williams SC, Hur HB, Murai-Yamamura M, Li X, Renert-Yuval Y, Estrada Y, Krueger JG, Guttman-Yassky E.  

Sphingosine 1-Phosphate Receptor 1 and 5 Reciprocally Regulate IL-13 and IL-9 Production in Atopic Dermatitis  

Allergy. 2026 Jul 

DOI: 10.1111/all.70299 

Yamamura K, Dahabreh D, Del Duca E, Lozano-Ojalvo D, Kim M, Murai-Yamamura M, Garcet S, Gonzalez J, Miura S, Williams SC, Hur HB, Li X, Liu Y, Lin XE, Metukuru R, Zhou J, Estrada YD, Krueger JG, Guttman-Yassky E.  

The OX40/OX40L Axis Promotes Th2 Activity and Impairs Regulatory T Cell Function in Atopic Dermatitis  

Allergy. 2026 Jul 

DOI: 10.1111/all.70252 

Lau M, Largen J, Del Duca E, He H, Guttman-Yassky E. 

The renaissance of therapeutic options in dermatology  

J Eur Acad Dermatol Venereol. 2026 Mar  

DOI: 10.1111/jdv.70121 

Lau M, Largen J, Levine J, Del Duca E, Mo L, Tan KJ, Liu D, Amangeldiyeva A, da Rosa JC, Edemobi P, Ungar B, Guttman-Yassky E.  

Long-Term Real-World Evaluation of Abrocitinib in Moderate-to-Severe Atopic Dermatitis Across a Diverse Patient Population in a Multi-site Hospital System  

Am J Clin Dermatol. 2026 Mar  

DOI: 10.1007/s40257-025-01004-z 

Liu D, Kim M, Del Duca E, Bar J, Lau M, Largen J, Agache I, Guttman-Yassky E.  

Skin tape strips identify age-specific immune, metabolic, and barrier dysregulation signatures in children, adolescents, and adults with allergic asthma

J Allergy Clin Immunol. 2026 Apr  

DOI: 10.1016/j.jaci.2025.11.016 

Bissonnette R, Saint-Cyr Proulx E, Correa da Rosa J, Estrada Y, Ren H, Nawaz H, Halden P, Stefani-Hunyady D, Popovic K, Volkova A, Smith SH, Guttman-Yassky E.  

Ruxolitinib cream demonstrated rapid reductions in itch and atopic dermatitis signs that correlated with biomarkers  

J Invest Dermatol. 2026 Jun 

DOI: 10.1016/j.jid.2025.10.613 

Glickman JW, David E, Shokrian N, Hawkins K, Duca ED, Hu BD, Navrazhina K, Carroll B, Mishra A, Estrada YD, Singer G, Krueger JG, Guttman-Yassky E.  

Large-Scale Blood Proteomic Analysis Across Different Inflammatory Skin Conditions Reveals Extensive Immune Dysregulation With Distinct Biomarker Profiles

Allergy. 2026 Feb 

DOI: 10.1111/all.70157 

2024

Rothenberg-Lausell C, Bar J, Del Duca E, Guttman-Yassky E.

Diversity of atopic dermatitis and selection of immune targets.

Ann Allergy Asthma Immunol. 2024 Feb

DOI: 10.1016/j.anai.2023.11.020

 

Leung DYM, Facheris P, Veverka KA, Cevikbas F, Guttman-Yassky E.

Targeting type 2 immune activation beyond atopic dermatitis

Ann Allergy Asthma Immunol. 2024 Feb.

DOI: 10.1016/j.anai.2023.06.028

 

 

Del Duca E, Dahabreh D, Kim M, Bar J, Da Rosa JC, Rabinowitz G, Facheris P, Gómez-Arias PJ, Chang A, Utti V, Chowdhury A, Liu Y, Estrada YD, Laculiceanu A, Agache I, Guttman-Yassky E.

Transcriptomic evaluation of skin tape-strips in children with allergic asthma uncovers epidermal barrier dysfunction and asthma-associated biomarkers abnormalities

Allergy. 2024 Jun.

DOI: 10.1111/all.16060

 

 

Croft M, Esfandiari E, Chong C, Hsu H, Kabashima K, Kricorian G, Warren RB, Wollenberg A, Guttman-Yassky E.

Correction to: OX40 in the Pathogenesis of Atopic Dermatitis-A New Therapeutic Target

Am J Clin Dermatol. 2024 May.

DOI: 0.1007/s40257-024-00850-7

 

 

Hawkins K, David E, Glickman JW, Del Duca E, Guttman-Yassky E, Krueger JG.

Atopic dermatitis stratification: current and future perspective on skin and blood transcriptomic and proteomic profiling.

Expert Rev Clin Immunol. 2024 Mar.

DOI: 10.1080/1744666X.2024.2323964

 

Navrazhina K, Renert-Yuval Y, Khattri S, Hamade H, Meariman M, Andrews E, Kim M, NandyMazumdar M, Gour DS, Bose S, Williams SC, Garcet S, Correa da Rosa J, Gottlieb AB, Krueger JG, Guttman-Yassky E.

Tape strips detect molecular alterations and cutaneous biomarkers in skin of patients with hidradenitis suppurativa.

J Am Acad Dermatol. 2024 Apr

DOI: 10.1016/j.jaad.2023.11.048

 

2023

Guttman-Yassky E, Facheris P, Gomez-Arias PJ, Del Duca E, Da Rosa JC, Weidinger S, Bissonnette R, Armstrong AW, Seneschal J, Eyerich K, Estrada YD, Bose SN, Xu D, Chen A, Tatulych S, Güler E, Chan G, Page KM, Kerkmann U.

Effect of abrocitinib on skin biomarkers in patients with moederate-to-severe atopic dermatitis.

Allergy. 2023

DOI: 10.1111/all.15969

Bissonnette R, DuBois J, Facheris P, Del Duca E, Kim M, Correa Da Rosa J, Trujillo DL, Bose S, Pagan AD, Wustrow D, Brockstedt DG, Wong B, Kassner PD, Jankicevic J, Ho W, Cheng LE, Guttman-Yassky E.

Clinical and molecular effects of oral CCR4 antagonist RPT193 in atopic dermatitis: A Phase 1 study

Allergy. 2023

DOI: 10.1111/all.15949

Guttman-Yassky E, Del Duca E, Da Rosa JC, Bar J, Ezzedine K, Ye Z, He W, Hyde C, Hassan-Zahraee M, Yamaguchi Y, Peeva E.

Improvements in immune/melanocyte biomarkers with JAK3/TEC family kinase inhibitor ritlecitinib in vitiligo.

J Allergy Clin Immunol. 2024 Jan

DOI: 10.1016/j.jaci.2023.09.021

Kim M, Renert-Yuval Y, Stepensky P, Even-Or E, Zaidman I, Fachler T, Neumark M, Zamir M, NandyMazumdar M, Gour D, Facheris P, Carroll B, Liu Y, Yu Ekey ML, Andrews E, Meariman M, Angelov M, Bose S, Estrada YD, Molho-Pessach V, Guttman-Yassky E.

Sclerotic-type cutaneous chronic graft-versus-host disease exhibitis activation of T helper 1 and OX40 cytokines.

J Invest Dermatol. 2023 Sep

DOI: 10.1016/j.jid.2023.08.026

Renert-Yuval Y, Del Duca E, Arents B, Bissonnette R, Drucker AM, Flohr C, Guttman-Yassky E, Hijnen D, Kabashima K, Leshem YA, Paller AS, Silverberg JI, Simpson EL, Spuls P, Vestergaard C, Wollenberg A, Irvine AD, Thyssen JP.

Treat-to-target in dermatology: A scoping review and International Eczema Council survey on the approach in atopic dermatitis

J Eur Acad Dermatol Venereol. 2024 Jan

DOI: 10.1111/jdv.19506

Dahabreh D, Jung S, Renert-Yuval Y, Bar J, Del Duca E, Guttman-Yassky E.

Alopecia areata: Current treatments and new directions

Am J Clin Dermatol. 2023 Nov

DOI: 10.1007/s40257-023-00808-1

Del Duca E, He H, Liu Y, Pagan AD, David E, Cheng J, Carroll B, Renert-Yuval Y, Bar J, Estrada YD, Maari C, Proulx ES, Krueger JG, Bissonnette R, Guttman-Yassky E.

Intrapatient comparison of atopic dermatitis skin transcriptome shows differences between tape-strips and biopsies

Allergy. 2024 Jan

DOI: 10.1111/all.15845

Kim M, Renert-Yuval Y, Stepensky P, Even-Or E, Zaidman I, Fachler T, Neumark M, Zamir M, NandyMazumdar M, Gour D, Facheris P, Carroll B, Liu Y, Yu Ekey ML, Andrews E, Meariman M, Angelov M, Bose S, Estrada YD, Molho-Pessach V, Guttman-Yassky E.

Sclerotic-type cutaneous chronic graft-versus-host disease exhibitis activation of T helper 1 and OX40 cytokines.

J Invest Dermatol. 2023 Sep

DOI: 10.1016/j.jid.2023.08.026