Publications

Liu D, Duca ED, Delaleu N, Lau M, Pulsinelli J, de Rosa JC, Bar J, Estrada Y, Gudjonsson J, Julia V, Guttman-Yassky E.  

Tape Strip Transcriptomics Reveal Nemolizumab Effects on Pruritus, Hyperplasia, Inflammation, and Extracellular Matrix Markers in Patients With Moderate-to-Severe Atopic Dermatitis 

Allergy. 2026 Sep 4 

DOI: 10.1111/all.70505 

Kim M, Del Duca E, Correa Da Rosa J, Pulsinelli J, Estrada Y, Xu D, Chan G, Chen A, Güler E, Page K, Guttman-Yassky E.  

Effect of Abrocitinib on the Skin Microbiome in Patients With Moderate-to-Severe Atopic Dermatitis  

Allergy. 2026 Aug 2 

DOI: 10.1111/all.70467 

Avallone G, Beaziz J, Manzo Margiotta F, Langer K, Del Duca E, Guttman-Yassky E.  

Atopic Dermatitis: New Targets and Emerging Systemic Therapies  

Am J Clin Dermatol. 2026 Jun 27. 

DOI: 10.1007/s40257-026-01054-x 

Sacknovitz Y, Ma R, Zhou MH, Kent J, Ng B, Erem AS, Litman T, Tolu SS, Pro B, Estrada YD, Guttman-Yassky E, Gru AA, Brunner PM, Geskin LJ. 

Serum proteomic and single-cell transcriptomic profiling reveals immunoproteomic features distinguishing early-stage mycosis fungoides from atopic dermatitis  

J Invest Dermatol. 2026 Jun 

DOI: 10.1016/j.jid.2026.05.026 

Zhou J, Fiedler J, Guttman-Yassky E.  

Beyond T helper 2 cells: Integrating immune, barrier, microbial, and neuroimmune pathways in atopic dermatitis pathogenesis  

J Am Acad Dermatol. 2026 May  

DOI: 10.1016/j.jaad.2026.01.076 

Beaziz J, Avallone G, Langer K, Del Duca E, Navrazhina K, He H, Guttman-Yassky E.  

Skin aging: Mechanistic insights and targeted therapeutic strategies  

J Allergy Clin Immunol. 2026 May 27 

DOI: 10.1016/j.jaci.2026.05.015 

Zhou J, Margiotta FM, Duca ED, Fiedler J, Cices A, Ungar B, Guttman-Yassky E.  

Comorbidities of atopic dermatitis: Emerging evidence and clinical considerations  

Ann Allergy Asthma Immunol. 2026 Jul 

DOI: 10.1016/j.anai.2026.04.015 

Kim M, Manson M, Liu Y, Rangel S, Kaplan N, Rabbaa L, Choate K, Bose S, Metukuru R, Lin X, Largen J, Shah M, Estrada YD, Paller AS, Guttman-Yassky E.  

Tape strips capture immune and epidermal hyperplasia markers in the major orphan ichthyoses  

J Invest Dermatol. 2026 Apr 

DOI: 10.1016/j.jid.2026.03.033 

Yamamura K, Garcet S, Gonzalez J, Zhou J, Fiedler J, Miura S, Williams SC, Hur HB, Murai-Yamamura M, Li X, Renert-Yuval Y, Estrada Y, Krueger JG, Guttman-Yassky E.  

Sphingosine 1-Phosphate Receptor 1 and 5 Reciprocally Regulate IL-13 and IL-9 Production in Atopic Dermatitis  

Allergy. 2026 Jul 

DOI: 10.1111/all.70299 

Lau M, Largen J, Del Duca E, He H, Guttman-Yassky E. 

The renaissance of therapeutic options in dermatology  

J Eur Acad Dermatol Venereol. 2026 Mar  

DOI: 10.1111/jdv.70121 

Lau M, Largen J, Levine J, Del Duca E, Mo L, Tan KJ, Liu D, Amangeldiyeva A, da Rosa JC, Edemobi P, Ungar B, Guttman-Yassky E.  

Long-Term Real-World Evaluation of Abrocitinib in Moderate-to-Severe Atopic Dermatitis Across a Diverse Patient Population in a Multi-site Hospital System  

Am J Clin Dermatol. 2026 Mar  

DOI: 10.1007/s40257-025-01004-z 

Liu D, Kim M, Del Duca E, Bar J, Lau M, Largen J, Agache I, Guttman-Yassky E.  

Skin tape strips identify age-specific immune, metabolic, and barrier dysregulation signatures in children, adolescents, and adults with allergic asthma

J Allergy Clin Immunol. 2026 Apr  

DOI: 10.1016/j.jaci.2025.11.016 

Glickman JW, David E, Shokrian N, Hawkins K, Duca ED, Hu BD, Navrazhina K, Carroll B, Mishra A, Estrada YD, Singer G, Krueger JG, Guttman-Yassky E.  

Large-Scale Blood Proteomic Analysis Across Different Inflammatory Skin Conditions Reveals Extensive Immune Dysregulation With Distinct Biomarker Profiles

Allergy. 2026 Feb 

DOI: 10.1111/all.70157 

David E, Shokrian N, Del Duca E, Meariman M, Dubin C, Hawkins K, Andrews E, Sikand S, Singer G, Oemar B, Estrada Y, Bose S, Pulsinelli J, Mahling P, Da Rosa JC, Ungar B, Peeva E, Guttman-Yassky E. 

A phase 2a trial of brepocitinib for cicatricial alopecia.

J Am Acad Dermatol. 2025 Mar

DOI: 10.1016/j.jaad.2024.09.073

Bar J, Del Duca E, David E, Bose S, Chefitz G, Brunner PM, Bissonnette R, Guttman-Yassky E. 

Skin Tape Stripping Reveals Distinct Biomarker Profiles in Chronic Hand Eczema of Patients With and Without Comorbid Atopic Dermatitis 

Allergy. 2025 Aug

DOI: 10.1111/all.16466

Gay-Mimbrera J, Lozano-Ojalvo D, Gómez-Arias PJ, Rivera-Ruiz I, Aguilar-Luque M, Mochón-Jiménez C, Andújar Pulido E, Pérez-Alegre M, Guttman-Yassky E, Ruano J. 

Comprehensive single-cell chromatin and transcriptomic profiling of peripheral immune cells in nonsegmental vitiligo

Br J Dermatol. 2025 Jun

DOI: 10.1093/bjd/ljaf041

Guttman-Yassky E, Renert-Yuval Y, Brunner PM.

Atopic dermatitis

Lancet. 2025 Feb

DOI: 10.1016/S0140-6736(24)02519-4

Brunner PM, David E, Del Duca E, Manson M, Kurowski A, Naidu MP, Port LR, Gay-Mimbrera J, Gómez-Arias PJ, Alkon N, Beaziz-Tordjman J, Estrada Y, Renert-Yuval Y, Ruano J, Guttman-Yassky E. 

Transcriptomic profiling of vitiligo patients shows polar immune dysregulation in involved and uninvolved skin

J Allergy Clin Immunol. 2025 Oct

DOI: 10.1016/j.jaci.2025.06.002

Powers CM, Kim M, Chang A, Hu BD, Block BR, Piontkowski AJ, Orloff J, Young JN, Estrada YD, Gour DS, Guttman-Yassky E, Gulati N.

Tape Strip Profiling of Checkpoint Inhibitor-Associated Dermatitis Highlights Pan-T-Cell Activation: A Pilot Study

JID Innov. 2025 May

DOI: 10.1016/j.xjidi.2025.100375

Liu D, Hu BD, Glickman J, O'Hagan R, He H, Guttman-Yassky E.

Artificial intelligence in atopic dermatitis: A narrative review

J Allergy Clin Immunol. 2025 Oct

DOI: 10.1016/j.jaci.2025.06.028

Liu D, Hu BD, Mishra A, Patel D, Lau M, Navrazhina K, He H, Guttman-Yassky E.

Tape strips in inflammatory skin disease: a noninvasive method for molecular insights and personalized care

Br J Dermatol. 2025 Oct

DOI: 10.1093/bjd/ljaf275

Verma H, Orloff J, Poplausky D, Block B, Young JN, Hu B, Piontkowski A, Rivera-Oyola R, Lalvani S, Rabinowitz G, Lambert R, Silver C, Powers C, Estrada Y, Zhou L, Suemitsu Y, Almonte D, Ekey KMY, Garcia-Barros M, Thin TH, Soto A, Brody R, Guttman-Yassky E, Brown R, Gulati N.

Safety, Tolerability, and Efficacy of Topical Diphencyprone for Cutaneous Neurofibromas: Results From a Phase I Clinical Trial

J Invest Dermatol. 2026 Apr

DOI: 10.1016/j.jid.2025.09.010

Ständer S, Guttman-Yassky E, Yosipovitch G, Wiegmann H, Metze D, Kim M, Del Duca E, Bondensgaard K, Paolini JF; LOTUS‐PN Investigators Group.

Unmasking prurigo nodularis endotypes: Dominant role of IL 31 dysregulation

J Eur Acad Dermatol Venereol. 2026 Feb

DOI: 10.1111/jdv.70137

Ungar B, Renert-Yuval Y, Dlova NC, Jabbari A, King B, Mesinkovska NA, Rudnicka L, Sinclair R, Guttman-Yassky E.

Alopecia areata

Nat Rev Dis Primers. 2025 Nov

DOI: 10.1038/s41572-025-00664-9

Glickman JW, David E, Shokrian N, Hawkins K, Duca ED, Hu BD, Navrazhina K, Carroll B, Mishra A, Estrada YD, Singer G, Krueger JG, Guttman-Yassky E.

Large-Scale Blood Proteomic Analysis Across Different Inflammatory Skin Conditions Reveals Extensive Immune Dysregulation With Distinct Biomarker Profiles

Allergy. 2026 Feb

DOI: 10.1111/all.70157

Rothenberg-Lausell C, Bar J, Del Duca E, Guttman-Yassky E.

Diversity of atopic dermatitis and selection of immune targets.

Ann Allergy Asthma Immunol. 2024 Feb

DOI: 10.1016/j.anai.2023.11.020

Leung DYM, Facheris P, Veverka KA, Cevikbas F, Guttman-Yassky E.

Targeting type 2 immune activation beyond atopic dermatitis

Ann Allergy Asthma Immunol. 2024 Feb.

DOI: 10.1016/j.anai.2023.06.028

Del Duca E, Dahabreh D, Kim M, Bar J, Da Rosa JC, Rabinowitz G, Facheris P, Gómez-Arias PJ, Chang A, Utti V, Chowdhury A, Liu Y, Estrada YD, Laculiceanu A, Agache I, Guttman-Yassky E.

Transcriptomic evaluation of skin tape-strips in children with allergic asthma uncovers epidermal barrier dysfunction and asthma-associated biomarkers abnormalities

Allergy. 2024 Jun.

DOI: 10.1111/all.16060

Hawkins K, David E, Glickman JW, Del Duca E, Guttman-Yassky E, Krueger JG.

Atopic dermatitis stratification: current and future perspective on skin and blood transcriptomic and proteomic profiling.

Expert Rev Clin Immunol. 2024 Mar.

DOI: 10.1080/1744666X.2024.2323964

Navrazhina K, Renert-Yuval Y, Khattri S, Hamade H, Meariman M, Andrews E, Kim M, NandyMazumdar M, Gour DS, Bose S, Williams SC, Garcet S, Correa da Rosa J, Gottlieb AB, Krueger JG, Guttman-Yassky E.

Tape strips detect molecular alterations and cutaneous biomarkers in skin of patients with hidradenitis suppurativa.

J Am Acad Dermatol. 2024 Apr

DOI: 10.1016/j.jaad.2023.11.048

Guttman-Yassky E, Facheris P, Gomez-Arias PJ, Del Duca E, Da Rosa JC, Weidinger S, Bissonnette R, Armstrong AW, Seneschal J, Eyerich K, Estrada YD, Bose SN, Xu D, Chen A, Tatulych S, Güler E, Chan G, Page KM, Kerkmann U.

Effect of abrocitinib on skin biomarkers in patients with moederate-to-severe atopic dermatitis.

Allergy. 2023

DOI: 10.1111/all.15969

Bissonnette R, DuBois J, Facheris P, Del Duca E, Kim M, Correa Da Rosa J, Trujillo DL, Bose S, Pagan AD, Wustrow D, Brockstedt DG, Wong B, Kassner PD, Jankicevic J, Ho W, Cheng LE, Guttman-Yassky E.

Clinical and molecular effects of oral CCR4 antagonist RPT193 in atopic dermatitis: A Phase 1 study

Allergy. 2023

DOI: 10.1111/all.15949

Guttman-Yassky E, Del Duca E, Da Rosa JC, Bar J, Ezzedine K, Ye Z, He W, Hyde C, Hassan-Zahraee M, Yamaguchi Y, Peeva E.

Improvements in immune/melanocyte biomarkers with JAK3/TEC family kinase inhibitor ritlecitinib in vitiligo.

J Allergy Clin Immunol. 2024 Jan

DOI: 10.1016/j.jaci.2023.09.021

Renert-Yuval Y, Del Duca E, Arents B, Bissonnette R, Drucker AM, Flohr C, Guttman-Yassky E, Hijnen D, Kabashima K, Leshem YA, Paller AS, Silverberg JI, Simpson EL, Spuls P, Vestergaard C, Wollenberg A, Irvine AD, Thyssen JP.

Treat-to-target in dermatology: A scoping review and International Eczema Council survey on the approach in atopic dermatitis

J Eur Acad Dermatol Venereol. 2024 Jan

DOI: 10.1111/jdv.19506

Dahabreh D, Jung S, Renert-Yuval Y, Bar J, Del Duca E, Guttman-Yassky E.

Alopecia areata: Current treatments and new directions

Am J Clin Dermatol. 2023 Nov

DOI: 10.1007/s40257-023-00808-1

Del Duca E, He H, Liu Y, Pagan AD, David E, Cheng J, Carroll B, Renert-Yuval Y, Bar J, Estrada YD, Maari C, Proulx ES, Krueger JG, Bissonnette R, Guttman-Yassky E.

Intrapatient comparison of atopic dermatitis skin transcriptome shows differences between tape-strips and biopsies

Allergy. 2024 Jan

DOI: 10.1111/all.15845