Publications

  1. MDM4 exon6-inclusion is a widespread oncogenic mechanism and therapeutic target Michael Dewaele*, Tommaso Tabaglio*, Karen Willekens*, Marco Bezzi*, Shun Xie Teo, Diana HP Low, Cheryl M Koh, […..] Jean-Christophe Marine# and Ernesto Guccione# J Clin Invest., 2016 Jan #Corresponding Authors
  2. Transcription and Imprinting Dynamics in Developing Postnatal Male Germline Stem Cells Saher Sue Hammoud, Diana HP Low, Chongil Yi, Chee Leng Lee, Jon Oatley, Christopher J. Payne, Douglas T. Carrell, Ernesto Guccione# and Bradley R. Cairns#  Genes Dev., 2015 Nov #Corresponding Authors
  3. Regulation of the core pre-mRNA splicing machinery by MYC is essential to sustain lymphomagenesis Cheryl M Koh*, Marco Bezzi*, Diana HP Low, Wei Xia Ang, Shun Xie Teo, Florence PH Gay, Muthafar Al-Haddawi, Soo Yong Tan, Motomi Osato, Arianna Sabò, Bruno Amati, Keng Boon Wee and Ernesto Guccione Nature, 2015 Jul 2;523(7558):96-100
  4. Telomerase subunit TERT regulates MYC dependent oncogenesis independent of its reverse transcriptase activity and role on telomeres
    Cheryl M Koh*, Ekta Khattar*, Shi Chi Leow, Chia Yi Liu, Julius Muller, Wei Xia Ang, Yinghui Li, Guido Franzoso, Shang Li, Ernesto Guccione# and Vinay Tergaonkar#  J Clin Invest., 2015 May;125(5):2109-22. #Corresponding Authors
  5. Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis. Sabò A, Kress TR, Pelizzola M, de Pretis S, Gorski MM, Tesi A, Morelli MJ, Bora P, Doni M, Verrecchia A, Tonelli C, Fagà G, Bianchi V, Ronchi A, Low D, Müller H, Guccione E, Campaner S, Amati B Nature, 2014 Jul 24;511(7510):488-92. Epub 2014 Jul 9.
  6. Chromatin and transcription transitions of Mammalian adult germline stem cells and spermatogenesis. Hammoud SS, Low DH, Yi C, Carrell DT, Guccione E#, Cairns BR# Cell Stem Cell, 2014 Aug 7;15(2):239-53 #Corresponding Authors
  7. Single-Cell Profiling of Epigenetic Modifiers Identifies PRDM14 as an Inducer of Cell Fate in the Mammalian Embryo Burton A*, Muller J*, Tu S, Padilla-Longoria P, Guccione E#, Torres-Padilla ME#  Cell Rep., 2013 Nov 14;5(3):687-701. #Corresponding Authors
  8. Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery
    Bezzi M, Teo SX, Muller J, Mok WC, Sahu SK, Vardy LA, Bonday ZQ, Guccione E Genes Dev., 2013 Sep 1;27(17):1903-16