Research

Latest Research Projects & Clinical Studies

Welcome to the Ensari Lab at the Icahn School of Medicine at Mount Sinai. We validate and implement mobile health technologies that help individuals with female chronic pelvic pain related conditions better understand and manage their health right from home.

Our Big Picture

Chronic pelvic pain (CPP) related conditions like endometriosis and fibroids affect millions of women, yet symptom patterns differ greatly from person to person and fluctuate day to day. Standard measures available for patients and clinicians to use to measure and characterize these conditions are substantially lacking and not disease-specific. This leads to a failure to capture the patient's daily reality and wellbeing accurately, diagnose in a timely manner, and provide effective treatments. Our mission is to bridge this gap by using AI and digital tools such as wearables and smartphone apps, to build personalized, real-time health insights and exercise strategies tailored to each individual's unique body and lifestyle.

Digital Health Monitoring in Chronic Pelvic Pain (CPP Tracker)

Developing accurate, disease-specific patient reported outcome measures that can capture the day-to-day changes in chronic pelvic pain related conditions to help patients manage their health and for clinicians to better tailor care.

What Participation Involves:

  • Daily Symptom Tracking: Use the Phendo and ehive smartphone Apps to log daily physical symptoms, mood, and self-management habits.
  • Weekly Surveys: Answer brief health and quality-of-life questionnaires via the ehive app.
  • Wearable Activity Insights: Wear a study-provided Fitbit tracker every day to collect sleep and movement metrics.
  • 100% Home-Based: Participate fully online from anywhere without in-person clinic visits.

Eligibility: Females 18–64 w/ diagnosed Chronic Pelvic Pain (6+ mos)

Duration: 90 Days (100% Remote, ~10 min/day)

Compensation: Keep study Fitbit + Up to $120

Routine Outcome Monitoring in Physical Therapy for Chronic Pelvic Pain (d²prom PT)

Measuring treatment response and progress in real time for individuals undergoing physical therapy for pelvic pain. 

What Participation Involves:

  • Track PT Progress: Log daily physical therapy exercises, physical function, symptoms, and mood via the ehive app.
  • Weekly Surveys: Complete brief weekly questionnaires about quality of life, pain impact, and PT progress through the ehive app.
  • Wearable Activity Insights: Wear a study-provided Fitbit tracker daily to record activity and sleep patterns.
  • No Change to Care: Continue your standard physical therapy regimen while logging progress from home.

Eligibility: Females 18–64 w/ Chronic Pelvic Pain starting or in PT

Duration: 12 Weeks (100% Remote, ~10 min/day)

Compensation: Keep study Fitbit + Up to $150

Personalized Exercise Recommendations for Pain Self-Management (WorkoutCPP)

Using smart technology and artificial intelligence to discover how tailored exercise routines can help individuals manage endometriosis-related pain.

The Problem: Generic exercise advice doesn't account for daily pain fluctuations. Our Approach: AI-driven personalized exercise prescriptions delivered and monitored remotely.

Eligibility: Females 18+ w/ diagnosis of a CPPD

Duration: 9 Weeks (100% Remote, ~5–10 min/day)

Compensation: Keep study Fitbit + Up to $180

What Participation Involves:

  • Personalized App Guidance: Follow tailored exercise recommendations delivered daily through the ehive smartphone app.
  • Daily Symptom Logging: Log your daily symptoms, health behaviors, and exercise responses via ehive.
  • Wearable Sensor: Wear a study-provided Fitbit tracker daily to track sleep, physical activity, and movement patterns.
  • Weekly Surveys: Complete short weekly surveys on quality of life and pain impact.