Publications

Our current research focuses on the mechnism of arteriovenous fistula failure

Aoyagi Y, Schwartz AW, Li Z, Bai H, Ho B, Lazcano-Etchebarne C, Gonzalez L, Ohashi Y, Kano M, Yatsula B, Ochoa Chaar CI, Martin K, Vazquez-Padron R, Dai G, Dardik A. Sox17 mediates venous adaptive remodeling after arteriovenous fistula creation. JVS Vasc Sci. 2025 Aug 28;6:100392. doi: 10.1016/j.jvssci.2025.100392. PMID: 41127450; PMCID: PMC12538405.

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Gonzalez LA, Zhang W, Bai H, Taniguchi R, Ramachandra AB, Jovin DG, Ohashi Y, Nguyen M, Thaxton C, Yatsula B, Vazquez-Padron RI, Humphrey JD, Martin KA, Kyriakides TR, Dardik A. Sustained tenascin-C expression drives neointimal hyperplasia and promotes aortocaval fistula failure. Am J Physiol Heart Circ Physiol. 2025 Jun 1;328(6):H1147-H1167. doi: 10.1152/ajpheart.00661.2024. Epub 2025 Apr 17. PMID: 40247455; PMCID: PMC12150301.

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Zhang W, Gonzalez L, Li X, Bai H, Li Z, Taniguchi R, Langford J, Ohashi Y, Thaxton C, Aoyagi Y, Yatsula B, Martin KA, Goodwin J, Tellides G, Long X, Shu C, Dardik A. Endothelial TGF-β Signaling Regulates Endothelial-Mesenchymal Transition During Arteriovenous Fistula Remodeling in Mice With Chronic Kidney Disease. Arterioscler Thromb Vasc Biol. 2024 Dec;44(12):2509-2526. doi: 10.1161/ATVBAHA.124.320933. Epub 2024 Sep 19. PMID: 39297205; PMCID: PMC11593991.

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Bai H, Li Z, Zhang W, Thaxton C, Ohashi Y, Gonzalez L, Kano M, Yatsula B, Hwa J, Dardik A. Early thrombus formation is required for eccentric and heterogeneous neointimal hyperplasia under disturbed flow. J Thromb Haemost. 2024 Dec;22(12):3614-3628. doi: 10.1016/j.jtha.2024.07.028. Epub 2024 Aug 21. PMID: 39173878; PMCID: PMC11608155.

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Bai H, Varsanik MA, Thaxton C, Ohashi Y, Gonzalez L, Zhang W, Aoyagi Y, Kano M, Yatsula B, Li Z, Pocivavsek L, Dardik A. Disturbed flow in the juxta-anastomotic area of an arteriovenous fistula correlates with endothelial loss, acute thrombus formation, and neointimal hyperplasia. Am J Physiol Heart Circ Physiol. 2024 Jun 1;326(6):H1446-H1461. doi: 10.1152/ajpheart.00054.2024. Epub 2024 Apr 5. PMID: 38578237; PMCID: PMC11380968.

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