Ilse S. Daehn, PhD
Division of Nephrology
Dr. Ilse Daehn is an Australian molecular and cell biologist with expertise in DNA damage and oxidative stress. She obtained her undergraduate in Biotechnology (Honors) and was awarded her Ph.D from the Flinders University of South Australia in 2008. She then pursued a postdoctoral fellowship at Cancer Research UK, London before joining Dr. Bottinger’s group at Icahn School of Medicine at Mount Sinai in 2010. She has been faculty at the Icahn School of Medicine at Mount Sinai since 2013. Her primary research interests are to understand the early molecular events involving mitochondria that occur and lead to chronic kidney disease. Her work has provided a fundamental paradigm shift in our current understanding of chronic kidney disease development and is now applying this knowledge to seek for biomarkers in the urine for early detection of disease and its progression. Dr. Daehn is also interested in exploring and evaluating the genetic susceptibility of individuals in the community to developing progressive kidney disease. Dr. Daehn is a leader in the scientific community actively involved in encouraging networking, collaboration and innovation among young researchers (kiiln.org).
Liping Yu is a Senior Associate Researcher int he Division of Nephrology and graduated from Jiangxi Medical College in China. She received a diploma in pharmacology from Jiangxi University of Traditional Chinese Medicine. She was a head pharmacist studying herbal medicines in China. In 2001, she joined Dr. Bottinger’s lab at Albert Einstein College of Medicine as a technician. She moved with the lab to Mount Sinai School of Medicine in 2004. Currently she is a senior research associate and lab manager, and is involved in the projects studying CKD biomarkers and podocytes-endothelium crosstalk by working with the faculty members and postdocs in the lab.
Dr. Emelie Lassén graduated with a Master of Science in Biotechnology from Chalmers University of Technology – Sweden, in 2015. She pursued her doctoral degree in Medical Science at the University of Gothenburg, focusing on the molecular mechanisms underlying IgA nephropathy. Following her defense in 2019 she worked as a researcher at the University of Gothenburg before joining the team as a postdoctoral fellow. Emelie joined the Daehn lab in September 2020 and is involved in projects investigating pathogenic crosstalk between endothelial cells in podocytes in early CKD, as well as the cell death mechanisms in AKI.
AFFILIATED FACULTY: Dr Avelino Teixeira has an extensive background in protein chemistry and as the former Director of the Proteomics Laboratory of the Department of Medicine at Mount Sinai Medical Center in New York. He has helped with the research of many different projects and has contributed to similar work to isolate HIV-suppressive proteins produced by CD8+ cells. I have also contributed all the protein work involved in separation and identification of a nucleic acid transporting channel that were detected in kidney cells. Dr Texiera is working on characterization of urinary biomarkers for CKD and using his advanced proteomics capabilities to identify key mediators in glomerular cell-cell crosstalk and injury.
Dr. Shuyu Li visiting scientist from Beijing University of Chinese Medicine, and Dr. Qin Wang visiting scientists from Chongqing Medical University, worked on understanding the genetic predisposition of mice strains to developing diabetic kidney disease. They studied mitochondrial function in the glomerular endothelium.
Dr. Gabriella Casalena is an alumnus of the University of Bologna – Italy where she graduated with honors in Molecular Biology. She pursued her doctoral research at the same university earning a PhD in Biochemistry. Before joining the lab in 2009 she was a visiting student at University of Kentucky, Lexington. Gabriella is involved in the investigation of the podocytes-endothelium crosstalk with a particular focus on the role of mitochondria (dys)function in the initiation and propagation of pathological pathways.