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Mount Sinai Center for Therapeutics Discovery

Mission: To discover innovative small-molecule therapeutics for the treatment of cancers and brain disorders via collaboration with investigators and clinicians.

Director:

Jian Jin, PhD.
Mount Sinai Endowed Professor in Therapeutics Discovery
Professor, Department of Pharmacological Sciences
Professor, Department of Oncological Sciences
Co-leader, Cancer Clinical Investigation Program, Tisch Cancer Institute

Dr. Jian Jin is an internationally recognized medicinal chemist with more than 20 years of experience in small-molecule drug discovery. He is currently the Mount Sinai Endowed Professor in Therapeutics Discovery, Professor in Departments of Pharmacological Sciences and Oncological Sciences, and the Director of the Mount Sinai Center for Therapeutics Discovery at Icahn School of Medicine at Mount Sinai (Mount Sinai). Dr. Jin’s laboratory is a leader in discovering selective inhibitors of histone methyltransferases, biased ligands of G protein-coupled receptors, and novel degraders targeting oncogenic proteins. Dr. Jin was an Associate Professor in the Division of Chemical Biology and Medicinal Chemistry at the University of North Carolina at Chapel Hill (UNC) and Associate Director of Medicinal Chemistry in the Center for Integrative Chemical Biology and Drug Discovery at UNC from 2008 to 2014. Dr. Jin was recruited to Mount Sinai as a professor with tenure in 2014. Dr. Jin has published >150 peer-reviewed papers and delivered >100 invited talks. He is also an inventor of >50 issued U.S. patents and published PCT patent applications. As the Director of the Mount Sinai Center for Therapeutics Discovery, Dr. Jin is leading research effort on discovering innovative therapeutics for the treatment of human diseases including cancer and brain disorders. Jin Lab Webpage

 

Associate Directors:

Arvin Dar, PhD.
Associate Professor, Department of Pharmacological Sciences
Associate Professor, Department of Oncological Sciences
Dar Lab Webpage

 

 

 

 

Ernesto Guccione, PhD.
Associate Professor, Department of Pharmacological Sciences
Associate Professor, Department of Oncological Sciences
Guccione Lab Webpage

 

 

Avner Schlessinger, PhD.
Assistant Professor, Department of Pharmacological Sciences
Schlessinger Lab Webpage

 

 

 

 

Daniel Wacker, PhD.
Assistant Professor, Department of Pharmacological Sciences
Assistant Professor, Department of Neuroscience
Wacker Lab Webpage

Assistant Director:

Ümit Kaniskan, PhD.
Assistant Professor, Department of Pharmacological Sciences