Publications

1.      La Merrill M, Sethi S, Benard L, Moshier E, Haraldsson B, & Buettner C (2016) Perinatal DDT exposure induces hypertension and cardiac hypertrophy in adult mice Environmental health perspectives. In press
2.      Ruiz HH, Chi T, Lindtner C, Hsieh W, Ehrlich M, Gandy S & Buettner C (2016) Increased Susceptibility to Metabolic Dysregulation in a Mouse Model of Alzheimer’s Disease is Associated with Impaired Hypothalamic Insulin Signaling and Elevated BCAA Levels. Alzheimers & Dementia. In press
3.      Scherer T, Lindtner C, Hare JO, Hackl M, Zielinski E, Freudenthaler A, Baumgartner-Parzer S, Tödter K, Heeren J, Krššák M, Scheja L, Fürnsinn C & Buettner C (2016) Insulin regulates hepatic triglyceride secretion and lipid content via signaling in the brain. Diabetes. Ahead of print February 9, 2016, doi:10.2337/db15-1552
4.      Knight EM, Klein WL, Ruiz HH, Attie AD, Kim SH, Buettner C, Harte JC,  Hsieh W, Ehrlich ME & Gandy S (2016) Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer’s APP/PSEN1 mice by gene targeting of diabetes/Alzheimer’s-related Sorcs1 Acta Neuropathologica comm. In press
5.      Kang S, Dahl R, Hsieh W, Shin AC, Zsebo KM, Buettner C, Hajjar RJ, Lebeche D.(2015) Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders. J Biol Chem. Dec 23. pii: jbc.M115.705012. [Epub ahead of print] PMID: 26702054.
6.      Jeong JH, Lee DK, Blouet C, Ruiz HH, Buettner C, Chua S Jr., Schwartz GJ & Jo Y-H (2015) Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism. Molecular Metabolism.  4(6):483-92.* PMID: 26042202.
7.      Sadahiro M, Erickson C, Lin W-J, Shin AC, Razzoli M, Jiang C, Fargali S, Gurney A, Kelley KA, Buettner C, Bartolomucci A & Salton SR (2015) Role of VGF-derived carboxy-terminal peptides in energy balance and reproduction:  analysis of ‘humanized’ knockin mice expressing full length or truncated VGF” Endocrinology 156(5):1724-38.* PMID: 25675362.
8.      Renault TT, Floros KV, Corrigan K-A, Kushnareva Y, Wieder S, Lindtner C, Serasinghe MS, Asciolla JJ, Buettner C, Newmeyer DD, and Chipuk JE (2015) Outer mitochondrial membrane shape engages BAX a9 to initiate terminal unfolded protein responses. Mol Cell, 57(1):69-82.* PMID: 25482509.
9.      Shin AC, Fasshauer M, Filatova N, Grundell LA, Zielinski E, Zhou JY, Scherer T, Lindtner C, White PJ, Lapworth AL, Ilkayeva O, Knippschild U, Wolf AM, Scheja L, Grove KL, Smith RD, Qian WJ, Lynch CJ, Newgard CB, Buettner, C. (2014) Brain Insulin Lowers Circulating BCAA Levels by Inducing Hepatic BCAA Catabolism. Cell Metab. pii: S1550-4131(14)00400-8. PMID: 25307860.*
10.     La Merrill, M., Karey, E., Moshier, E., Lindtner, C., La Frano, M.R., Newman, J.W., and Buettner, C. (2014). Perinatal Exposure of Mice to the Pesticide DDT Impairs Energy Expenditure and Metabolism in Adult Female Offspring. PLoS One 9, e103337. PMID: 25076055.*
11.     Howarth DL, Lindtner C, Vacaru AM, Sachidanandam R, Tsedensodnom O, Vasilkova T, Buettner C, Sadler KC  Activating Transcription Factor 6 is Necessary and Sufficient for Alcoholic Fatty Liver Disease in Zebrafish Plos Genetics  2014 May 29;10(5):e1004335. PMID: 24874946. *
12.     Iwen KA, Scherer T, Heni M, Sayk F, Wellnitz T, Machleidt F, Preissl H, Häring HU, Fritsche A, Lehnert H, Buettner C*, Hallschmid M* Intranasal insulin suppresses systemic but not subcutaneous lipolysis in healthy humans. J Clin Endocrinol Metab.  2014 Feb;99(2):E246-51. PMID: 24423295. PMCID: PMC3913807* corresponding authors. *
13.     Shalata A, Ramirez MC, Desnick RJ, Priedigkeit N, Buettner C, Lindtner C, Mahrom M,Abdul-Ghani M, Dong F, Camacho-Vanegas O, Zhang R, Camacho SC, Chen Y, Ibdah M, DeFronzo R, Gillespie V, Kelley K, Dynlacht BD, Kim S, Glucksman MJ, Borochowitz ZU, Martignetti JA. Morbid obesity in humans and mice resulting from inactivation of the ciliary protein MO1/C EP19. Am. J. Gen. 2013 Dec 5. PMID:24268657 PMCID: PMC3852924. *
14.     Garcia JM, Scherer T, Chen JA, Guillory B, Nassif A, Papusha V, Smiechowska J, Asnicar M, Buettner C, Smith RG. Inhibition of cisplatin-induced lipid catabolism and weight loss by ghrelin in male mice. Endocrinology. 2013 Jul 5. PMID: 23832960 PMCID:PMC3749475. *
15.     Eissing L, Scherer T, Todter K, Knippschild U, Greve JW, Buurman WA, Rensen SS, Wolf AM, Bartelt A, Heeren J, Pinnschmidt HO, Buettner C, Scheja L De novo lipogenesis in human fat and liver is linked to ChREBP-b and metabolic health. Nature Comm. 2013 Jan 23. PMID: 23443556 PMCID: PMC3740744. *
16.     Lindtner C, Scherer T, Zielinski E, Filatova N, Fasshauer M, Tonks NK,Puchowicz M, Buettner C. Binge drinking induces whole-body insulin resistance by impairing hypothalamic insulin action. Sci Transl Med. 2013 Jan 30;5(170):170ra14. PMID: 23363978 PMCID:PMC3740748. *
17.     Fargali S, Scherer T, Shin A, Sadahiro M, Buettner C, Salton SR.  Germline Ablation of VGF Increases Lipolysis in White Adipose Tissue. J Endocrinol. 2012 Aug 31. PMID: 22942234 PMCID:PMC3488863. *
18.     Scherer T, Lindtner C, Zielinski E, O’Hare J, Filatova N, Buettner C. Short–term voluntary overfeeding disrupts brain insulin control of adipose tissue lipolysis. J Biol Chem. 2012 287: 33061-33069. PMID:22810223 PMCID: PMC3463338. *
19.     Liu J, Zhou L, Xiong K, Godlewski G, Mukhopadhyay B, Tam J, Yin S, Gao P, Shan X, Pickel J, Bataller R, O’hare J, Scherer T, Buettner C, Kunos G. Hepatic Cannabinoid Receptor-1 Mediates Diet-Induced Insulin Resistance via Inhibition of Insulin Signaling and Clearance in Mice. Gastroenterology. 2012 May;142(5):1218-1228.e1. Epub 2012 Jan 31.PMID:22307032 PMCID:PMC3482511. *
20.     Scherer T, Buettner C. The Yin and Yang of hypothalamic insulin and leptin signaling in regulating white adipose tissue metabolism. Rev Endocr Metab Disord. 2011 Sep;12(3):235-43.PMID: 21713385 PMCID: PMC3253350.
21.     Scherer T, O’Hare J, Diggs-Andrews K, Schweiger M, Cheng B, Lindtner C, Zielinski E, Su K, Dighe S, Milsom T, Puchowicz M, Scheja L, Zechner R, Fisher SJ, Previs SF, Buettner C. Brain insulin controls adipose tissue function. Cell Met 2011 Feb; 13 (2): 183-194.PMID:21284985 PMCID:PMC3061443