Rendl Laboratory

Publications

Reviews

 

Heitman N#, Saxena N#, Rendl M.
Advancing insights into stem cell niche complexities with next-generation technologies.
Current Opinion in Cell Biology 2018, 55:87-95. pdf

 

Rezza A, Sennett R, Rendl M.
Adult Stem Cell Niches: Cellular and Molecular Components.
Current Topics in Developmental Biology 2014, 107C:333-372. pdf

 

Sennett R, Rendl M.
Mesenchymal-epithelial interactions during hair follicle morphogenesis and cycling.
Seminars in Cell Developmental Biology 2012, 23:917-27. pdf

 

 

Articles, Letters, Perspectives, Previews

 

Mok KW#, Saxena N#, Heitman N#, Grisanti L, Srivastava D, Muraro M, Jacob T, Sennett R, Su Y, Yang LM, Ma’ayan A, Ornitz DM, Kasper M, Rendl M.
Dermal Condensate Niche Fate Specification Occurs Prior to Formation and Is Placode Progenitor Dependent.
Developmental Cell 2019, 48:32-48. pdf

 

Mok KW#, Saxena N#, Rendl M.
More Than the Sum of Its Parts: Single-Cell Transcriptomics Reveals Epidermal Cell States.
Cell Reports 2018, 25:823-824. pdf

 

Rezza A, Wang Z, Sennett R, Qiao W, Wang D, Heitman N, Mok KW, Clavel C, Yi R, Zandstra P, Ma’ayan A, Rendl M.
Signaling Networks among Stem Cell Precursors, Transit-Amplifying Progenitors, and their Niche in Developing Hair Follicles.
Cell Reports 2016, 14:3001-18. pdf

 

Sennett R, Wang Z, Rezza A, Grisanti L, Roitershtein N, Sicchio C, Mok KW, Heitman NJ, Clavel C, Ma’ayan A, Rendl M.
An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin.
Developmental Cell 2015, Epub. pdf

 

Sennett R, Rendl M.
Developmental biology. A scar is born: origins of fibrotic skin tissue.
Science 2015, 348:284-5. pdf

 

Rezza A, Sennett R, Tanguy M, Clavel C, Rendl M.
PDGF signalling in the dermis and in dermal condensates is dispensable for hair follicle induction and formation.
Experimental Dermatology 2015, 24:468-70. pdf

 

Sennett R, Rezza A, Dauber KL, Clavel C, Rendl M.
Cxcr4 is transiently expressed in both epithelial and mesenchymal compartments of nascent hair follicles but is not required for follicle formation.
Experimental Dermatology 2014, 23:748-50. pdf

 

Tsai SY#, Sennett R#, Rezza A, Clavel C, Grisanti L, Zemla R, Najam S, Rendl M.
Wnt/β-catenin signaling in dermal condensates is required for hair follicle formation.
Developmental Biology 2014, 385:179-88. pdf

 

Grisanti L, Rezza A, Clavel C, Sennett R, Rendl M.
Enpp2/Autotaxin in Dermal Papilla Precursors is Dispensable for Hair Follicle Morphogenesis.
Journal of Investigative Dermatology 2013, 133:2332-9. pdf

 

Clavel C, Grisanti L, Zemla R, Rezza A, Barros R, Sennett R, Mazloom AR, Chung CY, Cai X, Cai CL, Pevny L, Nicolis S, Ma’ayan A, Rendl M.
Sox2 in the dermal papilla niche controls hair growth by fine-tuning BMP signaling in differentiating hair shaft progenitors.
Developmental Cell 2012, 23:981-994. pdf

 

Grisanti L, Clavel C, Cai-X, Rezza A, Tsai ST, Sennett R, Mumau M, Cai CL*, Rendl M*.
Tbx18 targets dermal condensates for labeling, isolation, and gene ablation during embryonic hair follicle formation.

Journal of Investigative Dermatology 2012, Sep 20, Epub. pdf

 

Tsai SY, Bouwman BAM, Ang YS, Kim S, Lee DF, Lemischka-IR, Rendl M.
Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells.
Stem Cells 2011, 29:964-71. pdf

 

Tsai SY, Clavel C, Kim S, Ang YS, Grisanti L, Lee DF, Kelley K, Rendl M.
Oct4 and Klf4 reprogram dermal papilla cells into induced pluripotent stem cells.
Stem Cells 2010, 28:221-8. pdf

 

Rendl M, Polak L, Fuchs E.
BMP signaling in dermal papilla cells is required for their hair follicle inductive properties.
Genes and Development 2008, 22:543-57. pdf

 

Rendl M, Lewis L, Fuchs E.
Molecular dissection of mesenchymal–epithelial interactions in the hair follicle. 
PLoS Biology 2005, 3(11): e331. pdf

 

 

Other selected publications (from a total of 38)

 

Siegle JM, Basin A, Sastre-Perona A, Yonekubo Y, Brown J, Sennett R, Rendl M, Tsirigos A, Carucci JA, Schober M.
SOX2 is a cancer-specific regulator of tumour initiating potential in cutaneous squamous cell carcinoma.
Nature Communications 2014, 5:4511. pdf

 

Ang YS, Tsai SY, Lee DF, Monk J, Su J, Ratnakumar K, Ding J, Ge Y, Darr H3, Chang B, Wang J, Rendl M, Bernstein E, Schaniel C, Lemischka IR.
Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional networke.
Cell 2011, 145:183-97. pdf

 

Driskell R, Clavel C, Rendl M*, Watt FM*.
Dermal Papilla Cells at a glance.
Journal of Cell Science 2011, 124:1179-82. pdf

 

Nguyen H, Merrill BJ, Polak L, Nikolova M, Rendl M, Shaver TM, Pasolli HA, Fuchs E.
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia.
Nature Genetics 2009, 41:1068-75. pdf

 

Greco V, Chen T, Rendl M, Schober M, Pasolli HA, Stokes N, Dela Cruz-Racelis J, Fuchs E.
A two-step mechanism for stem cell activation during hair regeneration.
Cell Stem Cell 2009, 4:155-69. pdf

 

Nguyen H, Rendl M, Fuchs E.
Tcf3 governs stem cell features and represses cell fate determination in skin.
Cell 2006, 127:171-83. pdf

 

Tumbar T, Guasch G, Greco V, Blanpain C, Lowry WE, Rendl M, Fuchs E.
Defining the epithelial stem cell niche in skin.
Science 2004, 303:359-63. pdf

 

#denotes equal contribution
* denotes co-corresponding author