The long-term goal of Yue Laboratory is to understand the molecular and cellular mechanisms of neurodegeneration that causes human neurological disorders such as Parkinson’s, Huntington’s and Alzheimer’s diseases. The laboratory’s mission is to translate their knowledge from basic research to the development of molecular diagnostics and therapeutics for neurological disorders. Yue Laboratory’s primary research interests encompass molecular and cellular pathways for autophagy-lysosome degradation, synaptic vesicle trafficking, neuroinflammation, and protein/lipid kinase signaling in neuropathogenesis.