Publications

Recent Publications
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Chamberlain, K., Riyad, J.M., and Weber, T. (2017). Cardiac gene therapy with adeno-associated virus-based vectors. Curr Opin Cardiol.

Chamberlain, K., Riyad, J.M. and Weber, T. (2016) Expressing Transgenes That Exceed the Packaging Capacity of Adeno-Associated Virus Capsids. Hum Gene Ther Methods 27, 1-12.

Nonnenmacher, M., van Bakel, H., Hajjar, R.J. and Weber, T. (2015) High capsid-genome correlation facilitates creation of AAV libraries for directed evolution. Mol Ther 23, 675-682.

Nonnenmacher, M.E., Cintrat, J.C., Gillet, D. and Weber, T. (2015) Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction. J Virol 89, 1673-1687.

Rapti, K., Stillitano, F., Karakikes, I., Nonnenmacher, M., Weber, T., Hulot, J.S. and Hajjar, R.J. (2015) Effectiveness of gene delivery systems for pluripotent and differentiated cells. Mol Ther Meth Clin Dev 2, 14067.

Chaanine, A.H., Nonnenmacher, M., Kohlbrenner, E., Jin, D., Kovacic, J.C., Akar, F.G., Hajjar, R.J. and Weber, T. (2014) Effect of bortezomib on the efficacy of AAV9.SERCA2a treatment to preserve cardiac function in a rat pressure-overload model of heart failure. Gene Ther 21, 379-386.

Ishikawa, K. et al. (2014) Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure. Mol Ther 22, 2038-2045.

Louis Jeune, V., Joergensen, J.A., Hajjar, R.J. and Weber, T. (2013) Pre-existing anti-adeno-associated virus antibodies as a challenge in AAV gene therapy. Hum Gene Ther Methods 24, 59-67.

Kohlbrenner, E., Henckaerts, E., Rapti, K., Gordon, R.E., Linden, R.M., Hajjar, R.J. and Weber, T. (2012) Quantification of AAV particle titers by infrared fluorescence scanning of coomassie-stained sodium dodecyl sulfate-polyacrylamide gels. Hum Gene Ther Methods 23, 198-203.

Nonnenmacher, M. and Weber, T. (2012) Intracellular transport of recombinant adeno-associated virus vectors. Gene Ther 19, 649-658.

Rapti, K., Louis-Jeune, V., Kohlbrenner, E., Ishikawa, K., Ladage, D., Zolotukhin, S., Hajjar, R.J. and Weber, T. (2012) Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models. Mol Ther 20, 73-83.

Tilemann, L., Ishikawa, K., Weber, T. and Hajjar, R.J. (2012) Gene therapy for heart failure. Circ Res 110, 777-793.

Nonnenmacher, M. and Weber, T. (2011) Adeno-associated virus 2 infection requires endocytosis through the CLIC/GEEC pathway. Cell Host Microbe 10, 563-576.

Complete Publication List