Mount Sinai Pilot Center for Precision Disease Modeling
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Our platform is developed for the community; please contact us for more information:

Project 1: Advancing Drosophila Platforms for Therapeutics Discovery

PI: Ross Cagan, PhD.

Professor in the Department of Developmental and Regenerative Biology and Director of the Center for Personalized Cancer Therapeutics

ross.cagan@mssm.edu

Project 2: Novel Approach to Developing Polypharmacological Lead Compounds

PI: Arvin Dar

Assistant Professor in the Departments of Oncological Sciences and Pharmacological Sciences

arvin.dar@mssm.edu

Project 3: Using Human Induced Pluripotent Stem Cells for Drug Discovery in the RASopathies

PI: Bruce Gelb

Professor in the Departments of Pediatrics, Cardiology, and Genetics and Genomic Sciences and Director, Mindich Child Health and Development Institute

bruce.gelb@mssm.edu

Project 4: PDX-TIC: A Novel Platform for Discovery and Validation of Therapeutic Targets

PI: Carlos Cordon-Cardo

Professor and Chairman of the Department of Pathology

carlos.cordon-cardo@mssm.edu

Steering Committee Members
Marshall Posner, MD
Professor of Medicine, Medical Director of the Head and Neck Oncology Center, and Associate Director of the Center for Personalized Cancer Therapeutics at the Mount Sinai Medical Center and the Icahn School of Medicine at Mount Sinai.
Robert Devita, PhD
Professor in the Departments of Pharmacology and Systems Therapeutics and Structural and Chemical Biology and the Director of the Medicinal Chemistry Core of the Experimental Therapeutics Institute at the the Icahn School of Medicine at Mount Sinai
Marek Mlodzik, PhD
Professor and Chair, Developmental and Regenerative Biology at the the Icahn School of Medicine at Mount Sinai

External Advisory Board Members
Laura Johnston, PhD
Professor of Genetics and Development at Columbia University
Frank McCormick, PhD, FRS, DSc
Professor Emeritus, UCSF Helen Diller Family Comprehensive Cancer Center, David A. Wood Distinguished Professorship of Tumor Biology and Cancer Research
Benjamin Neel, MD, PhD
Professor, Department of Medicine and Director of the Laura and Isaac Perlmutter Cancer Center
Norbert Perrimon, PhD
Professor of Genetics at Harvard Medical School and Investigator, Howard Hughes Medical Institute
Owen Sansom, PhD
Professor and Deputy Director, Beatson Institute for Cancer Research