Recent Publications

Mane V, Mehta R, Alvarez N, Sharma V, Park S, Fox A, DeCarlo C, Yang X, Perlin DS, Powell RLRIn vivo antiviral efficacy of LCTG-002, a pooled, purified human milk secretory IgA product, against SARS-CoV-2 in a murine model of COVID-19. Hum Vaccin Immunother2024 Dec 31;20(1):2303226. 2024 Jan 22.

Yang X, DeCarlo C, Fox A, Pineda N, Powell RLRAssessment of human milk samples obtained pre and post-influenza vaccination reveals a poor boosting of seasonally-relevant, hemagglutinin-specific antibodies. Front Immunol2023 May 31;14:1154782.

Yang, X, Fox, A, Norris, C, DeCarlo, C, Shenker, S, Powell, RL. Comparative profiles of SARS-CoV-2 Spike-specific human milk antibodies elicited by mRNA- and adenovirus-based COVID-19 vaccines. Breastfeed Med. 2022 Jun 8.

Fox A, Liu X, Zolla-Pazner S, Powell RL. Impact of IgG isotype on the induction of antibody-dependent cellular phagocytosis of HIV by human milk leukocytes. Front Immunol. 2022 May 3;13:831767.

Fox, A, Marino, J, Amanat, F, Oguntuyo, K, Hahn-Holbrook, J, Lee, B, Krammer, F, Zolla-Pazner, S, Powell RL. The IgA in milk induced by SARS-CoV-2 infection is comprised of mainly secretory antibody that is neutralizing and highly durable over time. PlosOne. 2022 Mar 9;17(3):e0249723.

Powell RL. Safety of breast/chest-feeding by those infected by SARS-CoV-2. Curr Opin Clin Nutr Metab Care. 2022 Mar 1;25(2):129-132.

Yang, X, Fox, A, Powell RL. Qualitative immunoassay for the detection of anti-SARS-COV-2 Spike antibody in human milk samples. STAR Protocols. 2022 Feb 14;3(1):101203.

Egwang, T, Owalla, T, Okurut, E, Apungia, G, Fox, A, DeCarlo, C, Powell RL. Differential pre-pandemic IgA reactivity against SARS-CoV-2 and circulating human coronaviruses measured in milk collected in Uganda and the USA. Int J Infect Dis. 2021 Sep 20; 112:165-172.

Spatz D, Davanzo R, Müller J, Powell RL, et. al. Promoting and Protecting Human Milk and Breastfeeding in a COVID-19 World. Front Pediatr. 2020; 8: 633700.

Fox A, Marino J, Amanat F, Krammer F, Hahn-Holbrook J, Zolla-Pazner S, Powell RL. Robust and specific secretory IgA against SARS-CoV-2 detected in human milk. iScience 2020 Nov 20; 23(11).

Powell RL, Weiss S, Fox A, Liu X, Itri V, Jiang X, Luo CC, Spencer DA, Pandey S, Cheever T, Fuller DH, Totrov M, Hessell AJ, Haigwood NL, Kong XP, Zolla-Pazner S. An HIV Vaccine Targeting the V2 Region of the HIV Envelope Induces a Highly Durable Polyfunctional Fc-Mediated Antibody Response in Rhesus Macaques. J Virol. 2020 Aug 17;94(17):e01175-20

Hessell AJ, Powell RL, Jiang X, et. al. Multimeric Epitope-Scaffold HIV Vaccines Target V1V2 and Differentially Tune Polyfunctional Antibody Responses. Cell Reports. Cell Rep. 2019 Jul 23;28(4):877-895.e6.

Powell RL and Fox A. Isolation of Leukocytes from Human Breast Milk for Use in an Antibody-Dependent Cellular Phagocytosis Assay of HIV Targets. J. Vis. Exp. (151)(2019)

Powell RL, Fox A, Liu X, Itri V. Phagocytosis of a Model Human Immunodeficiency Virus Target by Human Breast Milk Leukocytes Is Predominantly Granulocyte-Driven When Elicited by Specific Antibody. Breastfeed Med. 2019 Apr;14(3):185-192.

Powell RL, Fox A, Itri V, Zolla-Pazner S. Primary Human Neutrophils Exhibit a Unique HIV-Directed Antibody-Dependent Phagocytosis Profile. J Innate Immun. 2019;11(2):181-190.

A complete list of Dr. Powell’s publications can be found here.