Perez-Rodriguez Laboratory

Perez-Rodriguez Laboratory

Affective and Cognitive Therapeutics (ACT)

Our Research

 

Our research program investigates cognition, emotion processing and social functioning in serious mental illness, such as psychotic disorders and trauma-related disorders.

Our overall goal is to elucidate the biological mechanisms and environmental factors that contribute to impairments in cognition and social cognition, understand their relationship with functional outcomes, and test novel therapeutics to promote resilience and recovery.

Our translational research utilizes multimodal assessment methods including neuroimaging, psychophysiology, eye tracking, digital phenotyping, smartphone apps and devices, neuropsychological tests and behavioral tasks.

Current Projects

Biomarkers of Mother-Infant Social Behavior

Biomarkers of Mother-Infant Social Behavior
Principal Investigator:  Mercedes Perez-Rodriguez, MD, PhD

We seek to understand how hormonal changes that occur during pregnancy relate to maternal caregiving behavior. We will focus on the hormones oxytocin and vasopressin, which have been linked to regulating social behavior, including maternal caregiving. Through a unique collaboration with the obstetric anesthesia team at The Mount Sinai Hospital, we will measure these hormones in cerebrospinal fluid samples. These will be collected during anesthesia procedures that are routinely used for pain management during labor and delivery. The results of this study can help us to understand more about maternal caregiving behavior.

You are eligible to participate in this study if you plan to deliver at The Mount Sinai Hospital and will have epidural anesthesia for the delivery.

https://www.youtube.com/watch?v=BTR0HTu1hYQ

Repurposing of FDA-Approved Medication as a Novel Social Cognitive Enhancer

Repurposing of FDA-Approved Medication as a Novel Social Cognitive Enhancer

https://icahn.mssm.edu/research/affective-neuroscience/research

Social cognition, defined broadly as the ability to appropriately detect, interpret, and respond to social cues, is crucial for developing and maintaining social relationships. In many psychiatric disorders, such as spectrum, personality, or mood and anxiety disorders, or schizophrenia, social cognition is impaired, causing significant disability and difficulty with social functions.

Maria de las Mercedes Perez-Rodriguez, MD, PhD, and our team are investigating the brain mechanisms underlying abnormal social cognition, and testing the neuropeptide oxytocin as a new treatment. Oxytocin (pitocin) is a hormone approved by the FDA for the induction of labor, among other uses. Research data suggest that administering oxytocin through a nasal spray may cause changes in social cognition (PMID: 25153535).

Dr. Perez-Rodriguez’s team has shown that people with schizophrenia spectrum disorders experience impaired social cognition and poor social functioning (PMID: 23810511).

Dr. Perez-Rodriguez has teamed up with Prantik Kundu, PhD, and Scott Moeller, PhD, to develop new ways to assess real-life social cognition by combining, for the first time, a naturalistic social cognition experiment with functional brain imaging and eye-tracking technology.

Early results show that in patients with schizophrenia spectrum disorders, oxytocin increases their ability to notice social cues and understand them. These exciting data suggest that oxytocin could be repurposed to improve social cognition in psychiatric disorders.

 

Completed Projects:
  • 02/01/2019-8/31/2020 – Site PI. Study of Digital Health Technology. Goal: to test smartphone-based diagnostic tools for clinical trials. Takeda Pharmaceuticals
  • 07/01/18-08/31/2020 – PI. Emotion Processing, Cognition and Functioning in Comorbid Bipolar and Cocaine Use Disorders. Goal: to characterize the    sociodemographic and clinical features, cognitive, emotion processing and functional impairments of patients with comorbid Bipolar disorder (BD) and cocaine use disorders (CUD).
  • 4/1/2018-04/1/2020 –PI. Computational Diagnostics for Schizophrenic Patients with Negative Symptoms. AI Cure, LLC. AICVDX01. Goal: to test smartphone-based diagnostic tools for negative symptoms.
  • 11/20/17-11/19/19 – PI. Re-kinect Study: Real-world Evaluation Screening Study and Registry of Dyskinesia in Patients Taking Antipsychotic Agents. Neurocrine Biosciences, Inc. EVA-19350. Goal: understand possible side effects of antipsychotic medications.
  • 4/1/2013-4/28/2019 Co-I. A D1 agonist for working memory enhancement in the schizophrenia spectrum. NIH-funded grant 1R01MH097799-01A1. PI: New. Goal: to examine the effects of DAR-0100A -a dopamine-1 receptor (D1R) agonist- on working memory in schizotypal patients.
  • 9/1/2013-9/1/2019 – PI. Examining dose-related effects of oxytocin on social cognition across populations. CTSA (UL1TR000067)&VA MIRECC. Goal: To test the effect of intranasal oxytocin on social cognition.
  • 12/01/2015-11/30/2017 – PI. Examining Endophenotypes of Genetic Risk and Resiliency in Bipolar Disorder through Multimodal Measures of Emotional Processing. KL2 Faculty Scholar Award (KL2TR001435, CTSA). Goals: To uncover biomarkers of risk and resilience in bipolar disorder.
  • 01/14/2014-07/14/2017 – PI. Neuroimaging Endophenotypes In Patients With Bipolar Disorder And Unaffected Siblings. NARSAD Young Investigator Award, Goal: To uncover neuroimaging biomarkers of risk and resilience in bipolar disorder.
  • 7/23/2014-5/31/2017 Co-I: 1/2-Pramipexole in Bipolar Disorder: Targeting Cognition (PRAM-BD). 1R01MH102257-01A1. Goal: To test the effect of pramipexole to enhance cognition in bipolar disorder.
  • 8/22/2013-7/30/2017 Co-I: Targeting Circadian and Cognitive Dysfunction in Bipolar Disorder with Modafinil Goal: assess the efficacy of modafinil on sleep, daytime activity, and cognition.
  • 09/15/2014-09/14/2017 Co-I: A Molecular Approach to Treat Cognition in Schizophrenia: Ca2+ Channel Blockade. NARSAD. Goal: To assess the safety and feasibility of using isradipine in patients with schizophrenia.

Funding & Awards

 

  • U01 OH011473             Feder, Perez-Rodriguez (MPIs)                     07/01/17-06/30/21

Neuroimaging of Resilience in World Trade Center Responders: A Focus on Emotional Processing, Reward and Social Cognition

Goal: To uncover the neural bases of distinct mechanisms underlying resilience (e.g., emotion regulation, reward responses, social cognition).

Role: MPI

 

  • T32MH122394            Kahn, Malaspina, New, Perez-Rodriguez (MPIs) 07/01/2020-06/30/2025

Training the next generation of clinical neuroscientists

Goal: postdoctoral T32 program to train psychiatrists and clinical PhDs to conduct translational research in serious mental illness.

Role: MPI

 

  • R01MH121411 Hazlett, Szeszco (MPIs)                                             04/01/2020-03/31/2025

Longitudinal neuroimaging and neurocognitive assessment of risk and protective factors across the schizophrenia spectrum

The goal is to identify aberrant neural circuitry along a continuum from healthy controls to schizotypal personality disorder to recent-onset schizophrenia.

Role: Co-I

 

  • R01MH109730 Koenigsberg (PI)                                                                    09/23/16-06/30/21

Regulating Emotional Responses to Spoken comments and Visual Images Across the Affective Instability Spectrum: An fMRI Study

The goal is to determine whether emotional instability is associated with impairment in the ability to use effective emotion regulation mechanisms.

Role: Co-I

 

  • R25MH101074 New (PI)                                                                                             06/01/18 – 05/31/21

Combined Psychiatry Residency and PhD Training at Mount Sinai

This is a unique and innovative program for MDs, that allows trainees to complete PhD training in Neuroscience or Genomics and psychiatry residency simultaneously, over 7 years.

Role: Co-I

 

  • 1H7TI082569 Swift (PI)                                                                                09/30/19-09/29/22

Providers Clinical Support System at ISMMS

Goal: to increase the number of physicians prepared to provide MAT, specifically buprenorphine, in the treatment of persons who use opioids, by making DATA waiver training and education a mandatory component for all MD students at ISMMS (140/year)

Role: Co-I

 

Lab Publications

2020

1: Thompson JL, Rosell DR, Slifstein M, Xu X, Rothstein EG, Modiano YA, Kegeles

LS, Koenigsberg HW, New AS, Hazlett EA, McClure MM, Perez-Rodriguez MM, Siever

LJ, Abi-Dargham A. Amphetamine-induced striatal dopamine release in schizotypal

personality disorder. Psychopharmacology (Berl). 2020 Jun 22. doi:

10.1007/s00213-020-05561-5. Epub ahead of print. PMID: 32572588.

2019

2: McClure MM, Graff FS, Triebwasser J, Perez-Rodriguez MM, Rosell DR, Szeszko

PR, Chu KW, New AS, Siever LJ, Hazlett EA. Neuroimaging predictors of response

to cognitive remediation and social skills training: A pilot study in veterans

with schizophrenia. Psychiatry Res Neuroimaging. 2019 Nov 30;293:110988. doi:

10.1016/j.pscychresns.2019.110988. Epub 2019 Oct 8. PMID: 31655369.

 

3: Velikonja T, Velthorst E, McClure MM, Rutter S, Calabrese WR, Rosell D,

Koenigsberg HW, Goodman M, New AS, Hazlett EA, Perez-Rodriguez MM. Severe

childhood trauma and clinical and neurocognitive features in schizotypal

personality disorder. Acta Psychiatr Scand. 2019 Jul;140(1):50-64. doi:

10.1111/acps.13032. Epub 2019 Apr 23. PMID: 30951190.

 

4: Ospina LH, Shanahan M, Perez-Rodriguez MM, Chan CC, Clari R, Burdick KE.

Alexithymia predicts poorer social and everyday functioning in schizophrenia and

bipolar disorder. Psychiatry Res. 2019 Mar;273:218-226. doi:

10.1016/j.psychres.2019.01.033. Epub 2019 Jan 11. PMID: 30658205; PMCID:

PMC6561815.

2018

5: Perez-Rodriguez MM, Bulbena-Cabré A, Bassir Nia A, Zipursky G, Goodman M, New

  1. The Neurobiology of Borderline Personality Disorder. Psychiatr Clin North

Am. 2018 Dec;41(4):633-650. doi: 10.1016/j.psc.2018.07.012. PMID: 30447729.

 

6: Shameer K, Perez-Rodriguez MM, Bachar R, Li L, Johnson A, Johnson KW,

Glicksberg BS, Smith MR, Readhead B, Scarpa J, Jebakaran J, Kovatch P, Lim S,

Goodman W, Reich DL, Kasarskis A, Tatonetti NP, Dudley JT. Pharmacological risk

factors associated with hospital readmission rates in a psychiatric cohort

identified using prescriptome data mining. BMC Med Inform Decis Mak. 2018 Sep

14;18(Suppl 3):79. doi: 10.1186/s12911-018-0653-3. PMID: 30255805; PMCID:

PMC6156906.

 

7: Ospina LH, Nitzburg GC, Shanahan M, Perez-Rodriguez MM, Larsen E, Latifoglu

A, Burdick KE. Social cognition moderates the relationship between

neurocognition and community functioning in bipolar disorder. J Affect Disord.

2018 Aug 1;235:7-14. doi: 10.1016/j.jad.2018.03.013. Epub 2018 Mar 29. PMID:

29631204; PMCID: PMC6082404.

 

8: Stanley B, Perez-Rodriguez MM, Labouliere C, Roose S. A Neuroscience-Oriented

Research Approach to Borderline Personality Disorder. J Pers Disord. 2018 Feb

22:1-39. doi: 10.1521/pedi_2018_32_326. Epub ahead of print. PMID: 29469663.

 

9: Chan CC, Szeszko PR, Wong E, Tang CY, Kelliher C, Penner JD, Perez-Rodriguez

MM, Rosell DR, McClure M, Roussos P, New AS, Siever LJ, Hazlett EA. Frontal and

temporal cortical volume, white matter tract integrity, and hemispheric

asymmetry in schizotypal personality disorder. Schizophr Res. 2018

Jul;197:226-232. doi: 10.1016/j.schres.2018.01.025. Epub 2018 Feb 14. PMID:

29454512.

 

10: Berrouiguet S, Perez-Rodriguez MM, Larsen M, Baca-García E, Courtet P,

Oquendo M. From eHealth to iHealth: Transition to Participatory and Personalized

Medicine in Mental Health. J Med Internet Res. 2018 Jan 3;20(1):e2. doi:

10.2196/jmir.7412. PMID: 29298748; PMCID: PMC5772066.

 

11: Vora AK, Fisher AM, New AS, Hazlett EA, McNamara M, Yuan Q, Zhou Z,

Hodgkinson C, Goldman D, Siever LJ, Roussos P, Perez-Rodriguez MM. Dimensional

Traits of Schizotypy Associated With Glycine Receptor GLRA1 Polymorphism: An

Exploratory Candidate-Gene Association Study. J Pers Disord. 2018

Jun;32(3):421-432. doi: 10.1521/pedi_2017_31_303. Epub 2017 Jul 31. PMID:

28758885; PMCID: PMC5856645.

2017

12: Russo M, Van Rheenen TE, Shanahan M, Mahon K, Perez-Rodriguez MM, Cuesta-

Diaz A, Larsen E, Malhotra AK, Burdick KE. Neurocognitive subtypes in patients

with bipolar disorder and their unaffected siblings. Psychol Med. 2017

Dec;47(16):2892-2905. doi: 10.1017/S003329171700143X. Epub 2017 Jun 7. PMID:

28587689; PMCID: PMC5856455.

 

13: Perez-Rodriguez MM, New AS, Goldstein KE, Rosell D, Yuan Q, Zhou Z,

Hodgkinson C, Goldman D, Siever LJ, Hazlett EA. Brain-derived neurotrophic

factor Val66Met genotype modulates amygdala habituation. Psychiatry Res

Neuroimaging. 2017 May 30;263:85-92. doi: 10.1016/j.pscychresns.2017.03.008.

Epub 2017 Mar 24. PMID: 28371657; PMCID: PMC5856456.

2016

14: Goodman M, Banthin D, Blair NJ, Mascitelli KA, Wilsnack J, Chen J, Messenger

JW, Perez-Rodriguez MM, Triebwasser J, Koenigsberg HW, Goetz RR, Hazlett EA, New

  1. A Randomized Trial of Dialectical Behavior Therapy in High-Risk Suicidal

Veterans. J Clin Psychiatry. 2016 Dec;77(12):e1591-e1600. doi:

10.4088/JCP.15m10235. PMID: 27780335.

 

15: Ospina LH, Russo M, Nitzburg GM, Cuesta-Diaz A, Shanahan M, Perez-Rodriguez

MM, Mcgrath M, Levine H, Mulaimovic S, Burdick KE. The effects of cigarette

smoking behavior and psychosis history on general and social cognition in

bipolar disorder. Bipolar Disord. 2016 Sep;18(6):528-538. doi:

10.1111/bdi.12420. Epub 2016 Sep 21. PMID: 27650399.

 

16: Hazlett EA, Blair NJ, Fernandez N, Mascitelli K, Perez-Rodriguez MM, New AS,

Goetz RR, Goodman M. Startle amplitude during unpleasant pictures is greater in

veterans with a history of multiple-suicide attempts and predicts a future

suicide attempt. Psychophysiology. 2016 Oct;53(10):1524-34. doi:

10.1111/psyp.12698. Epub 2016 Jul 5. PMID: 27378071.

2015

17: Amad A, Thomas P, Perez-Rodriguez MM. Borderline Personality Disorder and

Oxytocin: Review of Clinical Trials and Future Directions. Curr Pharm Des.

2015;21(23):3311-6. doi: 10.2174/1381612821666150619093019. PMID: 26088114.

2014

20: Perez-Rodriguez MM, Baca-Garcia E, Oquendo MA, Wang S, Wall MM, Liu SM,

Blanco C. Relationship between acculturation, discrimination, and suicidal

ideation and attempts among US Hispanics in the National Epidemiologic Survey of

Alcohol and Related Conditions. J Clin Psychiatry. 2014 Apr;75(4):399-407. doi:

10.4088/JCP.13m08548. PMID: 24813407.

2013

21: Oquendo MA, Perez-Rodriguez MM, Poh E, Sullivan G, Burke AK, Sublette ME,

Mann JJ, Galfalvy H. Life events: a complex role in the timing of suicidal

behavior among depressed patients. Mol Psychiatry. 2014 Aug;19(8):902-9. doi:

10.1038/mp.2013.128. Epub 2013 Oct 15. PMID: 24126928; PMCID: PMC3988274.

 

22: Mahon K, Perez-Rodriguez MM, Gunawardane N, Burdick KE. Dimensional

endophenotypes in bipolar disorder: affective dysregulation and psychosis

proneness. J Affect Disord. 2013 Nov;151(2):695-701. doi:

10.1016/j.jad.2013.08.003. Epub 2013 Aug 14. PMID: 23993441; PMCID: PMC3844544.

 

23: Ripoll LH, Zaki J, Perez-Rodriguez MM, Snyder R, Strike KS, Boussi A, Bartz

JA, Ochsner KN, Siever LJ, New AS. Empathic accuracy and cognition in

schizotypal personality disorder. Psychiatry Res. 2013 Nov 30;210(1):232-41.

doi: 10.1016/j.psychres.2013.05.025. Epub 2013 Jun 28. PMID: 23810511.

 

24: New AS, Carpenter DM, Perez-Rodriguez MM, Ripoll LH, Avedon J, Patil U,

Hazlett EA, Goodman M. Developmental differences in diffusion tensor imaging

parameters in borderline personality disorder. J Psychiatr Res. 2013

Aug;47(8):1101-9. doi: 10.1016/j.jpsychires.2013.03.021. Epub 2013 Apr 28. PMID:

23628384; PMCID: PMC3725738.

2012

25: New AS, aan het Rot M, Ripoll LH, Perez-Rodriguez MM, Lazarus S, Zipursky E,

Weinstein SR, Koenigsberg HW, Hazlett EA, Goodman M, Siever LJ. Empathy and

alexithymia in borderline personality disorder: clinical and laboratory

measures. J Pers Disord. 2012 Oct;26(5):660-75. doi: 10.1521/pedi.2012.26.5.660.

PMID: 23013336.

 

26: Perez-Rodriguez MM, Hazlett EA, Rich EL, Ripoll LH, Weiner DM, Spence N,

Goodman M, Koenigsberg HW, Siever LJ, New AS. Striatal activity in borderline

personality disorder with comorbid intermittent explosive disorder: sex

differences. J Psychiatr Res. 2012 Jun;46(6):797-804. doi:

10.1016/j.jpsychires.2012.02.014. Epub 2012 Mar 29. PMID: 22464337; PMCID:

PMC3645307.

2011

27: Baca-Garcia E, Perez-Rodriguez MM, Oquendo MA, Keyes KM, Hasin DS, Grant BF,

Blanco C. Estimating risk for suicide attempt: are we asking the right

questions? Passive suicidal ideation as a marker for suicidal behavior. J Affect

Disord. 2011 Nov;134(1-3):327-32. doi: 10.1016/j.jad.2011.06.026. Epub 2011 Jul

  1. PMID: 21784532; PMCID: PMC3172880.

 

28: Perez-Rodriguez MM, Lopez-Castroman J, Martinez-Vigo M, Diaz-Sastre C,

Ceverino A, Núñez-Beltrán A, Saiz-Ruiz J, de Leon J, Baca-Garcia E. Lack of

association between testosterone and suicide attempts. Neuropsychobiology.

2011;63(2):125-30. doi: 10.1159/000318085. Epub 2010 Dec 30. PMID: 21196783.

2010

29: Baca-Garcia E, Perez-Rodriguez MM, Keyes KM, Oquendo MA, Hasin DS, Grant BF,

Blanco C. Suicidal ideation and suicide attempts among Hispanic subgroups in the

United States: 1991-1992 and 2001-2002. J Psychiatr Res. 2011 Apr;45(4):512-8.

doi: 10.1016/j.jpsychires.2010.09.004. PMID: 20937507; PMCID: PMC3032009.

 

30: Perez-Rodriguez MM, Weinstein S, New AS, Bevilacqua L, Yuan Q, Zhou Z,

Hodgkinson C, Goodman M, Koenigsberg HW, Goldman D, Siever LJ. Tryptophan-

hydroxylase 2 haplotype association with borderline personality disorder and

aggression in a sample of patients with personality disorders and healthy

controls. J Psychiatr Res. 2010 Nov;44(15):1075-81. doi:

10.1016/j.jpsychires.2010.03.014. Epub 2010 May 6. PMID: 20451217; PMCID:

PMC2955771.

 

31: Lopez-Castroman J, Gómez DD, Belloso JJ, Fernandez-Navarro P, Perez-

Rodriguez MM, Villamor IB, Navarrete FF, Ginestar CM, Currier D, Torres MR,

Navio-Acosta M, Saiz-Ruiz J, Jimenez-Arriero MA, Baca-Garcia E. Differences in

maternal and paternal age between schizophrenia and other psychiatric disorders.

Schizophr Res. 2010 Feb;116(2-3):184-90. doi: 10.1016/j.schres.2009.11.006. Epub

2009 Nov 28. PMID: 19945257.

 

32: Baca-Garcia E, Diaz-Sastre C, Ceverino A, Perez-Rodriguez MM, Navarro-

Jimenez R, Lopez-Castroman J, Saiz-Ruiz J, de Leon J, Oquendo MA. Suicide

attempts among women during low estradiol/low progesterone states. J Psychiatr

Res. 2010 Mar;44(4):209-14. doi: 10.1016/j.jpsychires.2009.08.004. Epub 2009 Sep

  1. PMID: 19782376.

 

33: Baca-Garcia E, Vaquero-Lorenzo C, Perez-Rodriguez MM, Gratacòs M, Bayés M,

Santiago-Mozos R, Leiva-Murillo JM, de Prado-Cumplido M, Artes-Rodriguez A,

Ceverino A, Diaz-Sastre C, Fernandez-Navarro P, Costas J, Fernandez-Piqueras J,

Diaz-Hernandez M, de Leon J, Baca-Baldomero E, Saiz-Ruiz J, Mann JJ, Parsey RV,

Carracedo A, Estivill X, Oquendo MA. Nucleotide variation in central nervous

system genes among male suicide attempters. Am J Med Genet B Neuropsychiatr

Genet. 2010 Jan 5;153B(1):208-13. doi: 10.1002/ajmg.b.30975. PMID: 19455598.

2009

34: Bermudo-Soriano CR, Vaquero-Lorenzo C, Diaz-Hernandez M, Perez-Rodriguez MM,

Fernandez-Piqueras J, Saiz-Ruiz J, Baca-Garcia E. SAT-1 -1415T/C polymorphism

and susceptibility to schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry.

2009 Mar 17;33(2):345-8. doi: 10.1016/j.pnpbp.2008.12.015. Epub 2009 Jan 3.

PMID: 19162121.

2008

35: Perez-Rodriguez MM, Baca-Garcia E, Diaz-Sastre C, Garcia-Resa E, Ceverino A,

Saiz-Ruiz J, Oquendo MA, de Leon J. Low serum cholesterol may be associated with

suicide attempt history. J Clin Psychiatry. 2008 Dec;69(12):1920-7. doi:

10.4088/jcp.v69n1210. Epub 2008 Oct 21. PMID: 19026260.

 

36: Baca-Garcia E, Perez-Rodriguez MM, Keyes KM, Oquendo MA, Hasin DS, Grant BF,

Blanco C. Suicidal ideation and suicide attempts in the United States: 1991-1992

and 2001-2002. Mol Psychiatry. 2010 Mar;15(3):250-9. doi: 10.1038/mp.2008.98.

Epub 2008 Sep 9. PMID: 18779820; PMCID: PMC2825279.

 

37: Vaquero-Lorenzo C, Riaza Bermudo-Soriano C, Perez-Rodriguez MM, Diaz-

Hernandez M, López-Castromán J, Fernandez-Piqueras J, Saiz-Ruiz J, Baca-Garcia

  1. Positive association between SAT-1 -1415T/C polymorphism and anxiety. Am J

Med Genet B Neuropsychiatr Genet. 2009 Jun 5;150B(4):515-9. doi:

10.1002/ajmg.b.30850. PMID: 18759322.

2007

38: Baca-Garcia E, Perez-Rodriguez MM, Basurte-Villamor I, López-Castromán J,

Fernandez del Moral AL, Jimenez-Arriero MA, Gronzalez de Rivera JL, Saiz-Ruiz J,

Leiva-Murillo JM, de Prado-Cumplido M, Santiago-Mozos R, Artés-Rodríguez A,

Oquendo MA, de Leon J. Diagnostic stability and evolution of bipolar disorder in

clinical practice: a prospective cohort study. Acta Psychiatr Scand. 2007

Jun;115(6):473-80. doi: 10.1111/j.1600-0447.2006.00984.x. PMID: 17498159.

 

39: Diaz-Sastre C, Baca-Garcia E, Perez-Rodriguez MM, Garcia-Resa E, Ceverino A,

Saiz-Ruiz J, Oquendo MA, de Leon J. Low plasma cholesterol levels in suicidal

males: a gender- and body mass index-matched case-control study of suicide

attempters and nonattempters. Prog Neuropsychopharmacol Biol Psychiatry. 2007

May 9;31(4):901-5. doi: 10.1016/j.pnpbp.2007.02.004. Epub 2007 Feb 15. PMID:

17363125.

 

40: Baca-Garcia E, Perez-Rodriguez MM, Basurte-Villamor I, Fernandez del Moral

AL, Jimenez-Arriero MA, Gonzalez de Rivera JL, Saiz-Ruiz J, Oquendo MA.

Diagnostic stability of psychiatric disorders in clinical practice. Br J

Psychiatry. 2007 Mar;190:210-6. doi: 10.1192/bjp.bp.106.024026. PMID: 17329740.

 

41: Lorenzo CV, Baca-Garcia E, Hernandez MD, Martin CB, Perez-Rodriguez MM,

Saiz-Gonzalez MD, Fernández P, Gutierrez FJ, Saiz-Ruiz J, Piqueras JF, de Rivera

JL, de Leon J. No association between the Ser9Gly polymorphism of the dopamine

D3 receptor gene and schizophrenia in a Spanish sample. Am J Med Genet B

Neuropsychiatr Genet. 2007 Apr 5;144B(3):344-6. doi: 10.1002/ajmg.b.30331. PMID:

17171662.

Maria de las Mercedes Perez-Rodriguez, MD, PhD
Assistant Professor of Psychiatry
Director, Medical Student Clerkship
Associate Director, Medical Student Education

Assistant Training Director for Research
Medical Director and Director of Research Training, Psychosis Research Program (Critical Connections)
Social Cognition Section Co-Chief, Center for Affective Neuroscience
Mercedes.perez@mssm.edu