Palese Laboratory

Virology, Influenza, Recombinant DNA

The Palese Laboratory and the Department of Microbiology focuses on fundamental questions concerning the genetic make-up and biology of viruses, as well as virus-host interactions.  They use molecular biological techniques to understand how viruses replicate and how they interact with cells to cause disease in their hosts.  Emphasis is on the study of RNA viruses, including influenza, paramyxo, and corona viruses.  There are three major research directions in the laboratory at the present time:  (1) the development of universal virus vaccine; (2) attempts to develop broad spectrum antiviral; (3) the development of novel vaccines for SARS-CoV-2 and their variants of concern (VOC).

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