[wds id=”12″] Josh A. Acklin, Ph.D. Candidate
Jan 2017-present
Josh received a Bachelor’s of Science in Microbiology and Immunology from the University of Rochester in 2017. He joined the PhD Program in 2017, and advanced to candidacy in early 2019. He has since worked on a variety of projects centering around the concept of host driven inflammation as a driver of pathology, in the context of viral infections. Josh’s work involves the generation of novel human tissue systems to study viral infections, and he has worked on a wide range of pathogens, including Zika, HPIV3, Measles, Mumps and SARS-COV-2. Outside of the lab, Josh is a major advocate for science in the NYC community, co-owning March for Science NYC and serving as one of its two Directors of Programming. He also enjoys spending his free time with his new kitten, Bowie, exploring the Hudson River Valley for hiking trails, and scoping out the best ramen joints in town.
Publications from the Lim Lab
- Tsetsarkin KA, Acklin JA, Liu G, Kenney H, Teterina NL, et al. (2020) Zika virus tropism during early infection of the testicular interstitium and its role in viral pathogenesis in the testes. PLOS Pathogens 16(7): e1008601. https://doi.org/10.1371/journal.ppat.1008601
- Brown JA*, Singh G*, Acklin JA*, Lee S, Duehr J, Chokola A, Frere JJ, Hoffman KW, Foster GA, Krysztof D, Cadagan R, Jacobs AR, Stramer SL, Krammer F, García-Sastre A, and Lim JK. Dengue virus immunity increases Zika virus-induced damage during pregnancy. Immunity. 2019 Jan 30. PMID: 30737148. *equal contribution
- Shukla R, Shanmugam RK, Ramasamy V, et al. Zika virus envelope nanoparticle antibodies protect mice without risk of disease enhancement. EBioMedicine. 2020;54:102738. doi:10.1016/j.ebiom.2020.102738
Marisa Goff, Ph.D. Student
Mar 2018-present
Marisa obtained her Bachelor’s degree in Microbiology, Immunology, and Molecular Genetics from the University of California, Los Angeles (UCLA) in 2018. Marisa is now studying host genetic factors that affect susceptibility to antibody-dependent enhancement of flavivirus infection. Outside of lab, she enjoys volunteering with cats at an animal shelter downtown, singing with the ISMMS student choir, hiking outside the city, and knitting more than most grandmothers.
Publications from the Lim Lab
- Wurster S, Robinson P, Albert ND, Tarrand JJ, Goff M, Swamydas M, Lim JK, Lionakis MS, Kontoyiannis DP. PD-1 blockade improves survival and fungal clearance, induces pro-inflammatory lung cytokines and synergizes with caspofungin in a pulmonary aspergillosis model. J Infect Dis. 2020 May 20;. doi: 10.1093/infdis/jiaa264. [Epub ahead of print] PubMed PMID: 32432714.
- Bouhaddou M, Memon D, Meyer B, White KM, Rezelj VV, Correa Marrero M, Polacco BJ, Melnyk JE, Ulferts S, Kaake RM, Batra J, Richards AL, Stevenson E, Gordon DE, Rojc A, Obernier K, Fabius JM, Soucheray M, Miorin L, Moreno E, Koh C, Tran QD, Hardy A, Robinot R, Vallet T, Nilsson-Payant BE, Hernandez-Armenta C, Dunham A, Weigang S, Knerr J, Modak M, Quintero D, Zhou Y, Dugourd A, Valdeolivas A, Patil T, Li Q, Hüttenhain R, Cakir M, Muralidharan M, Kim M, Jang G, Tutuncuoglu B, Hiatt J, Guo JZ, Xu J, Bouhaddou S, Mathy CJP, Gaulton A, Manners EJ, Félix E, Shi Y, Goff M, Lim JK, McBride T, O’Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, De Wit E, Leach AR, Kortemme T, Shoichet B, Ott M, Saez-Rodriguez J, tenOever BR, Mullins RD, Fischer ER, Kochs G, Grosse R, García-Sastre A, Vignuzzi M, Johnson JR, Shokat KM, Swaney DL, Beltrao P, Krogan NJ. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020 Jun 28;. doi: 10.1016/j.cell.2020.06.034. [Epub ahead of print] PubMed PMID: 32645325; PubMed Central PMCID: PMC7321036
Dania Figueroa, Ph.D. Student
2019-present
Dania received her Bachelor’s degree in Biochemistry at Wellesley College in 2017. Following a 2-year fellowship at the NIH, she joined ISMMS to pursue her PhD. Currently Dania is exploring different projects in the lab including understanding ZIKV pathogenesis in mice models. She is also passionate about improving diversity and inclusion efforts in STEM and holds several positions to this effect: Underrepresented in Medicine and STEM (URiSM) representative on Student Council, member of the MSHS Taskforce to Address Racism and member of the Graduate School Advisory Council. Outside of these two passions, Dania can be found jamming to Hamilton and knitting away!
Trinisia Fortune, Masters Student
2019-present
Trinisia obtained her Bachelor of Science degree in Biology from the City College of New York in 2016. Trinisia is currently developing new tissue-based models for the study of mumps virus infection in humans. Outside of lab, she likes to run marathons, travel, cook, loves the outdoors and is a huge foodie.
Ante Peros, Masters Student
2019-present
Ante obtained his Bachelor’s degree in Biology and Psychology from Hunter College in 2017. Ante is currently studying the enhancement of Zika virus pathogenesis in neonates through dengue-specific maternal antibodies. Outside of lab, Ante enjoys traveling and photography.
Javier Cattle, MPH Student
2019-present
Javier received his Bachelor’s of Arts in Biological Sciences from Columbia University and is currently an MPH student studying infectious disease epidemiology at the Mailman School of Public Health. In the lab, he studies host genetic factors implicated in symptom development and disease progression of Zika virus infection as well as enhancement of Zika virus pathogenesis in neonates through dengue-specific maternal antibodies. Outside of the lab, Javier enjoys the outdoors, traveling, getting lost exploring the city, and all things houseplants.
Aum Patel, MD-PhD Student
2019-present
Arianna Moss, Laboratory Technician
2020-present
Arianna received her Bachelor’s degree in Integrative Biology from the University of California, Berkeley. Outside of the lab, she loves rock climbing, running, and spending as much time outdoors as she can.