by hubmacherlab | Jun 27, 2019 | matrix biology, news, research
In a surprising twist, ADAMTSL2 gene expression was found in endothelial cells of the blood vessels in the forebrain (Supplemental Figure 6 in www.ahajournals.org/doi/full/10.1161/ATVBAHA.119.312388). However, it is absent in the vasculature outside of the brain. The...
by hubmacherlab | May 30, 2019 | conference, lab, news, research
Nandaraj’s abstract got selected for a podium presentation at the Gordon Research Seminar on Elastin, Elastic Fibers and Microfibrils. In addition, Stelios was chosen as a discussion leader for the keynote session.
by hubmacherlab | Feb 28, 2019 | matrix biology, news, publications, research
Geleophysic dysplasia is a short stature syndrome caused by mutations in ADAMTSL2 or FBN1. By deleting Adamtsl2 in the limb and in tendon, the Hubmacher lab developed a mouse model that has similar musculoskeletal features to patients with geleophysic dysplasia....
by hubmacherlab | Dec 20, 2018 | matrix biology, news, research, team, Uncategorized
The American Society for Matrix Biology interviewed Dr. Hubmacher for their most recent issue of “The Matrix Letter.” A copy of the newsletter can be found here: https://www.asmb.net/assets/docs/Newsletters/ML17-3.pdf
by hubmacherlab | Nov 14, 2018 | lab, news, team
We are pleased to welcome Sarah Stanley as a Master Student in the lab. She received her Bachelor of Science from the University of Massachusetts at Amherst and will be working on the role of ADAMTSL2 and other ECM proteins in skeletal muscle development. Welcome...
by hubmacherlab | Oct 26, 2018 | conference, lab, presentation, research, team
The first poster presentations from our lab contributed to a successful and inspiring meeting. We are already looking forward to the 2019 meeting! Nandaraj posing by his poster titled: “Deletion of Adamtsl2 in Mice Recapitulates the Musculoskeletal Features of...
by hubmacherlab | Oct 19, 2018 | conference, news, presentation, research
An abstract from the Hubmacher Lab was selected as a short talk for the ORS Tendon Section 2018 Conference “Discovery to Delivery in Tendon Research: Team Approaches”. Dirk will present the lab’s findings on the skeletal phenotype of a mouse model for geleophysic...
by hubmacherlab | Jul 16, 2018 | Uncategorized
We are pleased to announce that Stylianos (Stelios) Karoulias, PhD, has joined the Hubmacher lab as a Postdoctoral Fellow! He received his Ph.D. in Biochemistry from the Aristotle University of Thessaloniki (Greece) where he developed a novel biomaterial consisting...
by hubmacherlab | Jun 11, 2018 | team
We are pleased to announce that Nandaraj Taye, PhD, is joining the Hubmacher lab as a Postdoctoral Fellow! He completed his graduate studies in Biotechnology at Pune University’s National Centre for Cell Science in India and he will continue his career working on...
by hubmacherlab | May 31, 2018 | grants, lab, news, research
The Hubmacher lab received a microgrant from the Rare Disease Foundation and the BC Children’s Hospital Foundation in Canada. With this grant, we will study whether extracellular matrix function can be restored in cell lines derived from Marfan syndrome patients that...
