Hubmacher Laboratory

Nandaraj Taye, PhD


Postdoctoral Fellow, Orthopaedics
Icahn School of Medicine at Mount Sinai
nandaraj.taye@mssm.edu
LinkedIn

Hometown
Assam, India

Education
PhD in Biotechnology

Research
My research focuses on the role of the extracellular matrix in the formation and function of musculoskeletal tissues.

Publications: 

  1. Taye N et,al. SMAR1 inhibits Wnt/β-catenin signaling and negatively regulates colorectal cancer progression (Oncotarget). IF 5.16
  2. Chatterjee B, Banoth B, Mukherjee T, Taye N, Vijayaragavan B, Chattopadhyay S, Gomes J, Basak S. (2016) Delayed IkBa synthesis insulates TLR4 induced canonical RelA/NFkB pathway from non-canonical LTbR signaling in myelomonocytic cells. Science Signaling. IF 7.40
  3. Reddy GU, Axthelm J, Hoffmann P, Taye N, Glaser, Gorls H, Hopkins SL, Plass W, Nugebauer U, Bonnet S, and Schiller A. (2017) Co-registered molecular logic gate with a CO-releasing molecule triggered by light and peroxide. Journal of the American Chemical Society. IF 13.03
  4. Ramu V, Aute S, Taye N, Guha R, Walker MG, Mogare D, Parulekar A, Thomas JA, Chattopadhyay S, Das A. (2017) Photo-induced cytotoxicity and anti-metastatic activity of ruthenium(ii)-polypyridyl complexes functionalized with tyrosine or tryptophan. Dalton Transaction. IF 4.02
  5. Agarwalla H, Mahajan PS, Sahu D, Taye N, Bishwajit Ganguly B, Mhaske SB, Chattopadhyay S, Das A. (2016) A Switch-On NIR Probe for Specific Detection of Hg2+ Ion in Aqueous Medium and in Mitochondria. Inorganic Chemistry. IF 4.82
  6. Anila HA, Ali F, Kushwaha SA, Taye N, Chattopadhyay S, Das A. (2016) A Cysteine Specific Fluorescent Switch for Monitoring Oxidative Stress and Quantification of Aminoacylase1 in Blood Serum. Analytical Chemistry. IF 5.63
  7. Pal S, Ramu V, Taye N, Mogare DG, Yeware AM, Sarkar D, Reddy DS, Chattopadhyay S, Das A. (2016) GSH Induced Controlled Release of Levofloxacin form a Pur-pose-built Prodrug: Luminescence Response for Probing the Drug Release in E-coli and Staphylococcus aureus. Bioconjugate Chemistry. IF 4.51
  8. Ali F, Anila HA, Taye N, Mogare DG, Chattopadhyay S, Das A. (2016) Specific receptor for hydrazine: Mapping the in-situ release of hydrazine in live cells and in vitro enzymatic assay. Chemical Communications. IF 6.56
  9. Reddy GU, Ali F, Taye N, Chattopadhyay S, Das A. (2015) A new turn on Pd (2+)-specific fluorescence probe and its use as an imaging reagent for cellular uptake in Hct116 cells. Chemical Communication. IF 6.56
  10. Ramu V, Ali F, Taye N, Garai B, Alam Aftab, Chattopadhyay S and Das A. (2015) New Imaging Reagents for Lipid Dense Region in Live cells and Nucleus in Fixed MCF-7 cells. Journal of Materials Chemistry B. IF 4.87 3
  11. Anila HA, Ali F, Taye N, Chattopadhyay S, Das A. (2015) A reagent for specific recognition of cysteine in aqueous buffer and in natural milk: imaging studies, enzymatic reaction and analysis of whey protein. Chemical Communications. IF 6.56
  12. Ali F, Saha S, Maity A, Taye N, Si MK, Suresh E, Ganguly B, Chattopadhyay S, Das A. (2015) Specific Reagent for Cr (III): Imaging Cellular Uptake of Cr (III) in Hct116 Cells and Theoretical Rationalization. The Journal of Physical Chemistry B. IF 3.18
  13. Ali F, Anila HA, Taye N, Gonnade , RG, Chattopadhyay S, Das A. (2015) A fluorescent probe for specific detection of cysteine in the lipid dense region of cells. Chemical Communications. IF 6.56
  14. Reddy GU, Ali F, Taye N, Chattopadhyay S, Das A. (2015) FRET-Based Probe for Monitoring pH Changes in Lipid-Dense Region of Hct116 Cells. Organic letters. IF 6.73
  15. Reddy GU, Agarwalla H, Taye N, Ghorai S, Chattopadhyay S, Das A. (2014) A novel fluorescence probe for estimation of cysteine/histidine in human blood plasma and recognition of endogenous cysteine in live Hct116 cells. Chemical Communication. IF 6.56
  16. Reddy GU, Ramu V, Roy S, Taye N, Chattopadhyay S, Das A. (2014) A specific probe for Hg²⁺ to delineate even H⁺ in pure aqueous buffer/Hct116 colon cancer cells: Hg (II) η²- arene π-interaction and a TBET-based fluorescence response. Chemical Communication. IF 6.56

Patents

  1. Samit Chattopadhyay, Nandaraj Taye , Prabhat Salunke. A modified peptide as an anticancer agent. Application number WO2016139684A2/-PCT/IN2016/050081.
  2. Firoz Ali, Anila Hoeskere, Nandaraj Taye, Samit Chattopadhyay, Amitava Das. New reagent as scavenger of Hydrazine in drug induced cytotoxicity and in vitro enzymatic assay. Provisional Application No: 2332/DEL/2015
  3. Ramu Vadde, Nandaraj Taye, Samit Chattopadhyay, Amitava Das. Novel ruthenium (ii) complexes, preparation and uses thereof. Application number US20160102357A1/ US14878568.
  4. Firoj Ali, Anila Hoskere, Nandaraj Taye, Samit Chattopadhyay, Amitava Das. Selective determination of Free Cysteine. Provisional Application No: 2354/DEL/2015.
  5. Anil Hoeskere, Nandaraj Taye, Amitava Das, Samit Chattophadhyay. An ER-Specific reagent for monitoring HNO in biological objects. Provisional Application No: 201611041925 , Provisional filing date: 12/8/2016.

Poster Presentation 

  • Delivered talk at 17th Transcription Assembly Meeting (2014), India. Title “Wnt 3a activation inhibits tumor suppressor protein SMAR1 and in turn positively regulates Cyclin D1”.
  • Presented poster at International Conference of Cancer Research: New Horizons 2015, India. Won the third prize. Title “Role of SMAR1 in the Wnt signaling pathway”.

Awards

  • Awarded for “Council of Scientific and Industrial Research” fellowship to pursue PhD, 2010.
  • Awarded “National Eligibility Test” for eligibility to apply for teachings in Indian Universities, 2010.

Languages
Hindi, English, Assamese