Parkinson’s Disease

We are currently conducting studies seeking to identify the chemoanatomic basis for non-dopaminergic symptoms in Parkinson’s Disease (PD). Autonomic deficits including altered blood pressure regulation are common in PD patients, and may presage the hallmark motor symptoms of the disease by years. Understanding the pathophysiological basis for these autonomic deficits is likely to provide insight into the earliest cellular vulnerabilities occurring in PD, and may also provide a window for early diagnosis.