Selected Publications:

Casu C, Oikonomidou R, Chen H, Ginzburg Y, Prasad P, Fleming R, Shah Y, Nemeth E, Ganz T, MacDonald B, Rivella S. Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera. Blood. 2016, May 6; Epub ahead of print.

Chen H, Choesang T, Li H, Pham P, Bao W, Feola M, Westerman M, Li G, Follenzi A, Blanc L, Rivella S, Fleming R, Ginzburg Y. Increased hepcidin in transferrin-treated thalassemic mice correlates with decreased hepatocyte ERK activation. Haematologica. 2016 Mar;101(3):297-308.

Shenoy N, Vallumsetla N, Rachmilewitz E, Verma A, Ginzburg Y. Impact of iron overload and potential benefit from iron chelation in low-risk myelodysplastic syndrome. Blood, 2014;124(6):873-81.

Dussiot M, Maciel TT, Fricot A, Chartier C, Negre O, Veiga J, Grapton D, Paubelle E, Payen E, Beuzard Y, Leboulch P, Ribeil JA, Arlet JB, Coté F, Courtois G, Ginzburg YZ, Daniel TO, Chopra R, Sung V, Hermine O, Moura IC. The activin receptor IIa ligand trap Sotatercept corrects ineffective erythropoiesis in beta-thalassemia. Nat Med, 2014;20(4):398-407.

Liu J, Zhang J, Ginzburg Y, Li H, Xue F, De Franceschi L, Chasis JA, Mohandas N, An X. Quantitative analysis of murine terminal erythroid differentiation in vivo: Novel method to study normal and disordered erythropoiesis. Blood, 2013 Feb 21;121(8):e43-9.

Parrow NL, Gardenghi S, Ramos P, Casu C, Fleming RE, Grady RW, Li H, Ginzburg Y, Anderson ER, Shah YM, Rivella S. Decreased hepcidin expression in murine beta-thalassemia is associated with suppression of Bmp/Smad signaling. Blood. 2012;119(13):3187-9.

Ginzburg Y, Rivella S. β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism. Blood. 2011;118(16):4321-30.

Gardenghi S, Ramos P, Marongiu MF, Melchiori L, Breda L, Guy E, Muirhead K, Rao N, Roy CN, Andrews NC, Nemeth E, Follenzi A, An X, Narla M, Ginzburg Y, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S. Hepcidin as a therapeutic tool to limit iron overload and improve anemia in beta-thalassemia. J Clin Invest. 2010;120:4466-77.

Ramos P, Melchiori L, Gardenghi S, Van-Roijen N, Grady RW, Ginzburg Y, Rivella S. Iron metabolism and ineffective erythropoiesis in beta-thalassemia mouse models. Annals of the New York Academy of Sciences. 2010;1202:24-30.

Ramos E, Kautz L, Rodriguez R, Hansen M, Gabayan V, Ginzburg Y, Roth MP, Nemeth E, Ganz T. Evidence for distinct pathways of hepcidin regulation by extracellular and intracellular iron. Hepatology. 2011;53:1333-41.

Li H, Ginzburg Y. Crosstalk between iron metabolism and erythropoiesis. Advances in Hematology. 2010:605435.

Li H, Rybicki AC, Suzuka SM, von Bonsdorff L, Breuer W, Hall CB, Cabantchik ZI, Bouhassira  EE, Fabry ME, Ginzburg Y. Transferrin injection ameliorates disease in beta-thalassemic mice. Nat Med. 2010;16(2):177-82.

Ginzburg Y, Rybicki A, Suzuka S, Hall C, Breuer B, Cabantchik ZI, Bouhassira E, Fabry M, Nagel R. Exogenous iron increases hemoglobin in beta-thalassemic mice. Exp Hematol. 2009;37(2):172-83.

Mahesh S, Ginzburg Y*, Verma A*. Practical therapeutic implications of iron overload in myelodysplastic syndromes. Leukemia and Lymphoma 2008;49(3):427-38.* co- corresponding authors

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