Selected Publications

2021

A myeloid-stromal niche at gp130 rescue in NOD2-driven Crohn’s disease

Nayar S, Morrison JK, Giri M, Gettler K, Chuang LS, Walker LA, Ko HM, Kenigsberg E, Kugathasan S, Merad M, Chu J, Cho JH. A myeloid-stromal niche at gp130 rescue in NOD2-driven Crohn’s disease. Nature. 2021 Mar 31. PMID: 33789339.

 

AASLD Expert Panel Consensus Statement: Vaccines to Prevent COVID-19 Infection in Patients with Liver Disease

Fix OK, Blumberg EA, Chang KM, Chu J, Chung RT, Goacher EK, Hameed B, Kaul DR, Kulik LM, Kwok RM, McGuire BM, Mulligan DC, Price JC, Reau NS, Reddy KR, Reynolds A, Rosen HR, Russo MW, Schilsky ML, Verna EC, Ward JW, Fontana RJ; AASLD COVID-19 Vaccine Working Group. AASLD Expert Panel Consensus Statement: Vaccines to Prevent COVID-19 Infection in Patients with Liver Disease. Hepatology. 2021 Feb 12:10.1002/hep.31751. PMID: 33577086.

 

2020

Clinical Research in the SARS CoV-2 Pandemic and Post-Pandemic Era: Challenges and Need for Innovative Strategies

Verna E, Terrault N, Chu J, Loomba R, Serper M, Corey K, Garcia-Tsao L, Hoyt K, Fix O, Reddy KR, Chung RT. Clinical Research in the SARS CoV-2 Pandemic and Post-Pandemic Era: Challenges and Need for Innovative Strategies. Invited commentary, Hepatology. 2020 Aug; doi:10.1002/hep.31491. PMID: 32740969.

 

2019

Zebrafish modeling of intestinal injury, bacterial exposures, and medications define epithelial in vivo responses relevant to human inflammatory bowel disease

Chuang LS, Morrison J, Hsu NY, Labrias PR, Nayar S, Chen E, Villaverde N, Facey JA, Boschetti G, Giri M, Castillo-Martin M, Thin TH, Sharma Y, Chu J, Cho JH. Zebrafish modeling of intestinal injury, bacterial exposures, and medications define epithelial in vivo responses relevant to human inflammatory bowel disease. Dis Model Mech. 2019 Jul 23. [Epub ahead of print]. PMID: 31337664.

 

Hepatotoxicity in zebrafish larvae

Bambino K, Morrison J, Chu J. Hepatotoxicity in zebrafish larvae. Methods Mol Biol. 2019;1965:129-138. PMID: 31069672.

 

Mannose phosphate isomerase and mannose regulate hepatic stellate cell activation and fibrosis in zebrafish and humans

DeRossi C, Bambino K, Morrison J, Sakarin I, Villacorta-Martin C, Zhang C, Ellis JL, Fiel MI, Ybanez M, Lee YA, Huang KL, Yin C, Sakaguchi T, Friedman SL, Villanueva A, Chu J. Mannose phosphate isomerase and mannose regulate hepatic stellate cell activation and fibrosis in zebrafish and humans. Hepatology. 2019 Apr 23. PMID: 31016744.

 

2018

Autoimmune Hemolytic Anemia: An Unusual Presentation of Hemophagocytic Lymphohistiocytosis in a Pediatric Post-Liver Transplant Patient

Jarchin L, Chu J, Januska M, Merola P, Arnon R. Autoimmune Hemolytic Anemia: An Unusual Presentation of Hemophagocytic Lymphohistiocytosis in a Pediatric Post-Liver Transplant Patient. Pediatr Transplant. 2018 Nov;22(7):e13281. PMID: 30129086.

 

Pediatric Liver Transplant Teams’ Coping with Patient Death

Duncan SE, Arnon R, DiPietrantonio C, Ehrlich K, Knight CS, Chu J, Annunziato RA. Pediatric Liver Transplant Teams’ Coping with Patient Death. J Pediatr Gastroenterol Nutr. 2018 Apr 3. PMID: 29620594.

 

Inorganic arsenic causes fatty liver and interacts with ethanol to cause alcoholic liver disease in zebrafish

Bambino K, Zhang C, Austin C, Amarasiriwardena C, Arora M, Chu J, Sadler KC. Inorganic arsenic causes fatty liver and interacts with ethanol to cause alcoholic liver disease in zebrafish. Dis Model Mech. 2018 Feb 26;11(2). PMID: 29361514.

 

2017

Pediatric liver transplantation for fulminant hepatic failure secondary to intentional iron overdose

Lai J, Chu J, Arnon R. Pediatric liver transplantation for fulminant hepatic failure secondary to intentional iron overdose. Pediatr Transplant. 2017 Sep;21(6). PMID: 28621023.

 

MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect

Shtraizent N*, DeRossi C*, Nayar S, Sachidanandam R, Katz LS, Prince A, Koh AP, Vincek A, Hadas Y, Hoshida Y, Scott DK, Eliyahu E, Freeze HH, Sadler KC, Chu J. MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect, Elife, 2017 Jun 23:6. PMID: 28644127.

 

2016

Zebrafish in Toxicology and Environmental Health

Bambino K and Chu J. Zebrafish in Toxicology and Environmental Health. Curr Top Dev Biol. 2017; 124:331-367. Epub 2016 Dec 21. PMID: 28335683.

 

Liver Transplantation for Children with Primary Sclerosing Cholangitis and Autoimmune Hepatitis: UNOS Database Analysis

Jossen J, Annunziato R, Kim HS, Chu J, Arnon R. Liver Transplantation for Children with Primary Sclerosing Cholangitis and Autoimmune Hepatitis: UNOS Database Analysis. J Pediatr Gastroenterol Nutr. 2016 Oct 13. [Epub ahead of print] PMID: 27755342.

trappc11 is required for protein glycosylation in zebrafish and humans

DeRossi C, Vacaru A, Rafiq R, Cinaroglu A, Imrie D, Nayar S, Baryshnikova A, Milev MP, Stanga D, Kadakia D, Gao N, Chu J, Freeze HH, Lehrman MA, Sacher M, Sadler KC. trappc11 is required for protein glycosylation in zebrafish and humans. Molecular biology of the cell 2016 Feb.

 

2015

Liver Transplantation For Biliary Atresia: Is There A Difference In Outcome For Infants?

Arnon R, Annunziato RA, D’Amelio G, Chu J, Shneider BL. Liver Transplantation For Biliary Atresia: Is There A Difference In Outcome For Infants?. Journal of pediatric gastroenterology and nutrition 2015 Sep.

 

IgG4-Sclerosing Cholangitis in a Pediatric Patient

Rosen D, Thung S, Sheflin-Findling S, Lai J, Rosen A, Arnon R, Chu J. IgG4-Sclerosing Cholangitis in a Pediatric Patient. Seminars in liver disease 2015 Feb; 35(1).

 

Liver transplantation for neonatal hemochromatosis: Analysis of the UNOS database

Sheflin-Findling S, Annunziato RA, Chu J, Arvelakis A, Mahon D, Arnon R. Liver transplantation for neonatal hemochromatosis: Analysis of the UNOS database. Pediatric transplantation 2015 Jan.

 

Epstein-Barr virus-associated smooth muscle tumors in children following solid organ transplantation: A review

Jossen J, Chu J, Hotchkiss H, Wistinghausen B, Iyer K, Magid M, Kamath A, Roayaie S, Arnon R. Epstein-Barr virus-associated smooth muscle tumors in children following solid organ transplantation: A review. Pediatric transplantation 2015 Jan.

 

2014

Balloon-occluded retrograde transvenous obliteration for recurrent fundal gastric variceal bleeding in an adolescent

Rosen D, Chu J, Patel R, Moon J, Iyer K, Arnon R. Balloon-occluded retrograde transvenous obliteration for recurrent fundal gastric variceal bleeding in an adolescent. Pediatric transplantation 2014 Sep; 18(6).

 

2013

Hepatitis C Virus-Autoimmune Hepatitis Overlap Syndrome in an Adolescent: Case Report and Review of the Literature

Rosen D, Chu J, Morotti R, Levanon D, Rose S, Lee S, Arnon R. Hepatitis C Virus-Autoimmune Hepatitis Overlap Syndrome in an Adolescent: Case Report and Review of the Literature. Journal of pediatric gastroenterology and nutrition 2013 Dec;.

 

Liver transplantation for children with biliary atresia in the pediatric end-stage liver disease era: the role of insurance status

Arnon R, Annunziato RA, Willis A, Parbhakar M, Chu J, Kerkar N, Shneider BL. Liver transplantation for children with biliary atresia in the pediatric end-stage liver disease era: the role of insurance status. Liver transplantation: official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2013 May; 19(5).

 

A zebrafish model of congenital disorders of glycosylation with phosphomannose isomerase deficiency reveals an early opportunity for corrective mannose supplementation

Chu J, Mir A, Gao N, Rosa S, Monson C, Sharma V, Steet R, Freeze HH, Lehrman MA, Sadler KC. A zebrafish model of congenital disorders of glycosylation with phosphomannose isomerase deficiency reveals an early opportunity for corrective mannose supplementation. Disease models & mechanisms 2013 Jan; 6(1).

 

Psychosocial outcomes for children with nonalcoholic fatty liver disease over time and compared with obese controls

Kerkar N, D’Urso C, Van Nostrand K, Kochin I, Gault A, Suchy F, Miloh T, Arnon R, Chu J, Annunziato R, Sadler KC. Psychosocial outcomes for children with nonalcoholic fatty liver disease over time and compared with obese controls. Journal of pediatric gastroenterology and nutrition 2013 Jan; 56(1).

 

2012

Partial internal biliary diversion for Alagille syndrome: case report and review of the literature

Sheflin-Findling S, Arnon R, Lee S, Chu J, Henderling F, Kerkar N, Iyer K. Partial internal biliary diversion for Alagille syndrome: case report and review of the literature. Journal of pediatric surgery 2012 Jul; 47(7).

 

UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis

Chu J, Loughlin EA, Gaur NA, SenBanerjee S, Jacob V, Monson C, Kent B, Oranu A, Ding Y, Ukomadu C, Sadler KC. UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis. Molecular biology of the cell 2012 Jan; 23(1).

 

2011

Roux-en-Y loop varies in children with portal hypertension after liver transplantation: an unusual cause of “obscure” gastrointestinal bleeding

Chu J, Kerkar N, Miloh TA, Rodriguez-Laiz G, Lewis B, Stangl A, Newton KP, Iyer K, Arnon R, Sadler KC. Roux-en-Y loop varies in children with portal hypertension after liver transplantation: an unusual cause of “obscure” gastrointestinal bleeding. Pediatric transplantation 2011 Dec; 15(8).

 

2009

New school in liver development: lessons from zebrafish

Chu J, Sadler KC. New school in liver development: lessons from zebrafish. Hepatology 2009 Nov; 50(5).