October 2022 – Dr. Nai-yun Hsu’s paper “NOX1 is essential for TNFα-induced intestinal epithelial ROS secretion and inhibits M cell signatures” is published in Gut. Congratulations to all of the authors!
Find more updates from the Cho Lab here.
About the Cho Lab
The Cho Laboratory investigates the genetic and immunologic factors associated with Crohn’s Disease and Ulcerative Colitis, collectively known as Inflammatory Bowel Diseases (IBD). We are part of the Department of Genetics and Genomic Sciences, at the Icahn School of Medicine at Mount Sinai, NY.
A major focus of our research is understanding the prevalence of IBD in the Ashkenazi Jewish population. We are working on further identifying rare disease associated variants in Ashkenazi Jewish population by Exome Chip technology as well as the biological function of those identified genes. Dr. Cho’s research has contributed to defining the pathophysiologic mechanisms of IBD by identifying associations to NOD2, IL23R, and 163 loci to IBD. With new findings our research is evolving to now looking at the function of lipid mediators and their related cytokines in innate immune cells, and the full transcriptome of enteroids, the intestinal epithelial stem cells.