Our current research interests are divided into three areas, and adopts a unified theme to decipher the interplay between mitochondrial biology and cancer mechanisms:
1) Mechanistic insights of how mitochondrial composition, shape, and number impact on cellular metabolism and commitment to apoptosis
2) Explore how cancer-promoting pathways converge on the mitochondrial function to regulate malignancy and chemotherapeutic success
3) To reveal novel contributions of the mitochondrial network in skin homeostasis, with a focus on melanocytes and melanomagenesis
The laboratory is a highly collaborative group on the Mount Sinai campus, which has enriched our scientific impact and experimental skill set — along with creating an ideal atmosphere for mentoring students and post-doctoral fellows.